Accès ouvert
2007
article
OpenAlex
Brigitte Kircher, Dietger W. Niederwieser, Anne Gächter, Beate Lindner et autres
Functional assays measuring alloreactivity of donor cells are desired to detect either cryptic epitopes inducing graft-vs.-host disease (GvHD) after human leukocyte antigen (HLA)-identical hematopoietic stem cell transplantation (HSCT) or permissible HLA mismatches. However, their value in predicting GvHD and survival is still …
at
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Accès ouvert
2003
article
OpenAlex
Brigitte Kircher, Karla Lätzer, Günther A. Gastl, David Nachbaur
Humanized or chimeric monoclonal antibodies (MoAbs) directed against the interleukin-2 (IL-2) receptor alpha-chain, CD25, are promising immunosuppressive agents due to improved pharmacokinetic profiles and less toxicity. These MoAbs have been used effectively in preventing and/or treating rejection in solid organ transplantation and …
at
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Accès ouvert
2003
article
OpenAlex
David Nachbaur, Brigitte Kircher, Klaus Eisendle, Karla Lätzer et autres
Dendritic cells (DCs) are essential for initiating T-cell responses against either host- or leukaemia-specific antigens. We analysed phenotype, allostimulatory capacity and chimaerism of monocyte-derived DCs (moDCs) serially in 28 patients receiving allogeneic stem cell grafts after conventional myeloablative (n = 14) or …
at
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2002
article
OpenAlex
Brigitte Kircher, G. Eibl, Barbara Enrich, Karla Lätzer et autres
INTRODUCTION: The amino acid glutamine plays an important role in the immune system by providing energy and precursors for biosynthetic processes. For lack of stability it could not so far be generally supplied in total parenteral nutrition. The development of dipeptides consisting …
at
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2000
article
OpenAlex
David Nachbaur, Gaby Kropshofer, Andreas Heitger, Karla Lätzer et autres
To determine the effect of CD34+ selection on immune recovery after high-dose chemo/radiotherapy in the setting of autologous stem cell transplantation (ASCT), we analyzed quantitative and qualitative lymphocyte reconstitution for up to 1 year post-transplantation in 27 consecutive adult patients receiving either …
at, de
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