Sara Zia-Chahabi

Tinzaparin Pharmacokinetics in Patients with Cancer: A Comparative Modeling Study

Xavier Delavenne, Jean Escal, Dominique Helley, Laurent Bertoletti et autres

Abstract Cancer-associated thrombosis (CAT) is common and a leading cause of mortality in patients with cancer. In specific CAT scenarios, low-molecular-weight heparins (LMWHs), including tinzaparin, are preferred over direct oral anticoagulants. Despite the importance of understanding LMWH pharmacokinetics (PK) in cancer for …

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An update on anti-protein Z antibodies

Tiffany Pascreau, Sara Zia-Chahabi, Tojoniaina-Herinjaka Andriamandimbisoa, Marc Vasse

Protein Z (PZ) is a vitamin K-dependent protein that acts as a cofactor for the inhibition of activated factor X by the PZ-dependent protease inhibitor, an anticoagulant protein of the serpin superfamily. The presence of antibodies against PZ (aPZ-Abs) was first described …

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Letter to the editor regarding “Protein Z and Protein Z-dependent protease inhibitor in patients with acute ischemic stroke: A prospective mechanistic study”

Tiffany Pascreau, Sara Zia-Chahabi, Marc Vasse

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Comparison of two SARS-CoV-2 RT-PCR assays and implication of the instrument software on cycle threshold (Ct) value

Éric Farfour, Tiffany Pascreau, Sara Zia-Chahabi, Émilie Jolly et autres

The Cycle Threshold (Ct) value of SARS-CoV-2 RT-PCR are used as an indicator of viral load. Using a collection of 45 fresh nasopharyngeal samples collected on universal transport media, we compare the Ct value obtained with 2 RT-PCR assays, the Alinity M …

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An Immunogenicity Report for the Comparison between Heterologous and Homologous Prime-Boost Schedules with ChAdOx1-S and BNT162b2 Vaccines

Alexandre Vallée, Marc Vasse, Laurence Mazaux, Brigitte Bonan et autres

Background: There is a small amount of immunological data on COVID-19 heterologous vaccination schedules in humans. We assessed the immunogenicity of BNT162b2 (Pfizer/BioNTech) administered as a second dose in healthcare workers primed with ChAdOx1-S (Vaxzevria, AstraZeneca). Methods: 197 healthcare workers were included …

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Association of Protein Z with Prediabetes and Type 2 Diabetes (Endocrinol Metab 2021;36:637-46, Yun-Ui Bae et al.)

Tiffany Pascreau, Maia Tchikviladze, Émilie Jolly, Sara Zia-Chahabi et autres

International audience

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SARS-CoV-2 screening of asymptomatic health care workers: experience of a General hospital

Éric Farfour, C Amiel, Marion Lecuru, Sara Zia-Chahabi et autres

week following the implementation of the guidelines. The number of tests performed each week in HCWs increased by at least 20-fold after the implementation of the guidelines. No asymptomatic HCW was tested positive. Screening of asymptomatic HCWs was poorly effective in the …

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Direct oral anticoagulant neutralization by activated charcoal DOAC-Remove for thrombophilia screening

Rémy Favre, Sara Zia-Chahabi, Yasmina Talb, Noémie de Gunzburg et autres

Favre, Rémy; Zia-Chahabi, Sara; Talb, Yasmina; de Gunzburg, Noémie; Flaujac, Claire Author Information

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The high frequency of anti-PF4/heparin antibodies in patients with COVID-19 is neither related to heparin treatment or to an increased incidence of thrombosis

Tiffany Pascreau, Marie‐Christine Ballester, Patrick Van Dreden, Sara Zia-Chahabi et autres

Article The high frequency of anti-PF4/heparin antibodies in patients with COVID-19 is neither related to heparin treatment or to an increased incidence of thrombosis was published on October 1, 2021 in the journal Clinical Chemistry and Laboratory Medicine (CCLM) (volume 59, issue …

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Spring is coming, where are the Respiratory Syncytial Virus and Influenza viruses?

Éric Farfour, Tiffany Pascreau, Émilie Jolly, Sara Zia-Chahabi et autres

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The ID NOW COVID-19, a high-speed high-performance assay

Éric Farfour, Marianne Asso‐Bonnet, Marc Vasse, Émilie Catherinot et autres

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ADAMTS 13 deficiency is associated with abnormal distribution of von Willebrand factor multimers in patients with COVID-19

Tiffany Pascreau, Sara Zia-Chahabi, Benjamin Zuber, Colas Tchérakian et autres

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