Abbas Abdoli

CCDC 2313620: Experimental Crystal Structure Determination

W. Cameron Black, Abbas Abdoli, Xiuli An, Anick Auger et autres

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, …

Discovery of the Potent and Selective ATR Inhibitor Camonsertib (RP-3500)

W. Cameron Black, Abbas Abdoli, Xiuli An, Anick Auger et autres

ATR is a key kinase in the DNA-damage response (DDR) that is synthetic lethal with several other DDR proteins, making it an attractive target for the treatment of genetically selected solid tumors. Herein we describe the discovery of a novel ATR inhibitor …

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Isolated Trochlea Fracture: A Rare Case Report

Abbas Abdoli, Ali Sharifat Salmani

Background: Trochlea fracture usually happens with other fractures such as capitellum fracture or medial or lateral condyle fracture and isolated trochlea fracture is very rare because of its location and there are only a few cases of isolated trochlea fracture that have …

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Попытка разграничения видов рода Carassius (Cyprinidae) с использованием морфологии и связанные с этим проблемы: тематическое исследование во внутренних водах Ирана

M. Khosravi, Abbas Abdoli, Ф. Таджбахш, Ф. Ахмадзаде et autres

Phytoalexins and Signalling Metabolites Produced in the Wild Crucifer Neslia Paniculata: Camalexins and Arabidopsides

M. Soledade C. Pedras, Mahla Alavi, Abbas Abdoli

The metabolites produced in elicited leaves of the wild crucifer Neslia paniculata (L.) Desv. were investigated in abiotically stressed plants. Herein the phytoalexins camalexin, 7-methoxycamalexin and 6,7-dimethoxycamalexin together with the signalling metabolites arabidopsides A and D are reported. This is the first …

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Phytoalexins and Signalling Metabolites Produced in the Wild Crucifer Neslia Paniculata: Camalexins and Arabidopsides

M. Soledade C. Pedras, Mahla Alavi, Abbas Abdoli

The metabolites produced in elicited leaves of the wild crucifer Neslia paniculata (L.) Desv. were investigated in abiotically stressed plants. Herein the phytoalexins camalexin, 7-methoxycamalexin and 6,7-dimethoxycamalexin together with the signalling metabolites arabidopsides A and D are reported. This is the first …

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Phytoalexins and Signalling Metabolites Produced in the Wild Crucifer Neslia Paniculata: Camalexins and Arabidopsides

M. Soledade C. Pedras, Mahla Alavi, Abbas Abdoli

The metabolites produced in elicited leaves of the wild crucifer Neslia paniculata (L.) Desv. were investigated in abiotically stressed plants. Herein the phytoalexins camalexin, 7-methoxycamalexin and 6,7-dimethoxycamalexin together with the signalling metabolites arabidopsides A and D are reported. This is the first …

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Ecological Roles of Tryptanthrin, Indirubin and N‐Formylanthranilic Acid in Isatis indigotica: Phytoalexins or Phytoanticipins?

M. Soledade C. Pedras, Abbas Abdoli, Quang Huy To, Chintamani Thapa

Leaves of the plant species Isatis indigotica Fortune ex Lindl. (Chinese woad) produce the metabolites tryptanthrin, indirubin and N-formylanthranilic acid upon spraying with an aqueous solution of copper chloride but not after spraying with water. The antifungal activities of these metabolites against …

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Methoxycamalexins and related compounds: Syntheses, antifungal activity and inhibition of brassinin oxidase

M. Soledade C. Pedras, Abbas Abdoli

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Inhibitors of the Detoxifying Enzyme of the Phytoalexin Brassinin Based on Quinoline and Isoquinoline Scaffolds

M. Soledade C. Pedras, Abbas Abdoli, Vijay K. Sarma‐Mamillapalle

The detoxification of the phytoalexin brassinin to indole-3-carboxaldehyde and S-methyl dithiocarbamate is catalyzed by brassinin oxidase (BOLm), an inducible fungal enzyme produced by the plant pathogen Leptosphaeria maculans. Twenty-six substituted quinolines and isoquinolines are synthesized and evaluated for antifungal activity against L. …

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Pathogen inactivation of cruciferous phytoalexins: detoxification reactions, enzymes and inhibitors

M. Soledade C. Pedras, Abbas Abdoli

This review covers the detoxification pathways of cruciferous phytoalexins, the corresponding detoxifying enzymes and their natural and synthetic inhibitors. Paldoxins are examined as a potentially sustainable strategy to control plant pathogenic fungi.

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Biotransformation of rutabaga phytoalexins by the fungus Alternaria brassicicola: Unveiling the first hybrid metabolite derived from a phytoalexin and a fungal polyketide

M. Soledade C. Pedras, Abbas Abdoli

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