2026
article
OpenAlex
Cindy Serrato Zavala, Chloé Huyghe, Sujan Timilsina, Bindhu Verghese
Accurate microbial identification remains a crucial component of quality control and safety in the pharmaceutical industry. Among various methods of microbial identification, proteotypic-based MALDI-TOF (Matrix Assisted Laser Desorption/Ionization Time-of-Flight) technology has emerged as a rapid, high-throughput, and cost-effective method for microbial identification. …
nl, us, de
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2026
article
OpenAlex
Sujan Timilsina, Ryan Cox, Ruvim Kolosey, Bindhu Verghese
Microbial identification and strain typing are critical in pharmaceutical microbiology for ensuring product safety, controlling contaminants, and meeting regulatory requirements. Traditional strain typing methods like pulsed-field gel electrophoresis and multi-locus sequence typing have their limitations in scalability and resolution. Increased use of …
nl, gb, us, de
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Accès ouvert
2025
article
OpenAlex
Sujan Timilsina, Fernanda Iruegas-Bocardo, Mustafa O. Jibrin, Anuj Sharma et autres
Emerging and re-emerging plant diseases continue to present multifarious threats to global food security. Considerable recent efforts are therefore being channeled towards understanding the nature of pathogen emergence, their spread and evolution. Xanthomonas euvesicatoria pv. perforans (Xep), one of the causal agents …
us, Nigéria, it, mx, vn, Afrique du Sud, Éthiopie, cn, ir, br, au, ca, th
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Accès ouvert
2024
article
OpenAlex
Shaheen Bibi, Gerald V. Minsavage, Joana Figueiredo, Sujan Timilsina et autres
Many phytopathogenic bacteria require a type III secretion system (TTSS) to activate effector-triggered immunity (ETI). We identified a calcium-binding protein, EfhXXfa, in the citrus pathogen Xanthomonas citri subsp. aurantifolii that does not require a TTSS to activate reactive oxygen species (ROS) and …
us
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Accès ouvert
2024
article
OpenAlex
Mustafa O. Jibrin, Anuj Sharma, Carla Mavian, Sujan Timilsina et autres
The emergence of plant pathogens is often associated with waves of unique evolutionary and epidemiological events. Xanthomonas hortorum pv. gardneri is one of the major pathogens causing bacterial spot disease of tomatoes. After its first report in the 1950s, there were no …
us, Nigéria, Afrique du Sud, Éthiopie, uy, ph, fr, re, br, gb, ca
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2024
article
OpenAlex
Apekshya Parajuli, Aastha Subedi, Sujan Timilsina, Gerald V. Minsavage et autres
Bacterial spot caused by Xanthomonas spp. is an economically important disease of pepper causing significant yield losses in Taiwan. Monitoring the pathogen population on a continuous basis is necessary for developing disease management strategies. We analyzed a collection of xanthomonad strains isolated …
us, tw
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2024
article
OpenAlex
Sujan Timilsina, Amandeep Kaur, Anuj Sharma, Gary E. Vallad et autres
In this review, we highlight studies in which whole-genome sequencing, comparative genomics, and population genomics have provided unprecedented insights into past and ongoing pathogen evolution. These include new understandings of the adaptive evolution of secretion systems and their effectors. We focus on …
us
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Accès ouvert
2024
preprint
OpenAlex
Sujan Timilsina, Fernanda Iruegas-Bocardo, Mustafa O. Jibrin, Anuj Sharma et autres
Abstract Emerging and re-emerging plant diseases continue to present multifarious threats to global food security. Considerable recent efforts are therefore being channeled towards understanding the nature of pathogen emergence, their spread and evolution. Xanthomonas euvesicatoria pv. perforans (Xep ), one of the …
us, it, mx, vn, Afrique du Sud, co, Éthiopie, cn, ir, br, au, Nigéria, th, ca
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Accès ouvert
2024
article
OpenAlex
Mrinal Shrestha, Anish Joshi, Ajit Kumar Pandey, Aashutosh Chaudhary et autres
Background. Acute disseminated encephalomyelitis (ADEM) is a rare immune‐mediated pathology involving inflammatory demyelination of the central nervous system. Case Presentation. In this case report, we present the case of a nine‐year‐old female who exhibited altered mental status and focal neurological deficit, subsequently …
np
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Accès ouvert
2023
article
OpenAlex
Anuj Sharma, Sujan Timilsina, Peter Abrahamian, Gerald V. Minsavage et autres
Rapidly evolving bacterial pathogens pose a unique challenge for long-term plant disease management. In this study, we investigated the types and rate of mutations in bacterial populations during seasonal disease epidemics. Two phylogenetically distinct strains of the bacterial spot pathogen, Xanthomonas perforans, …
us
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2023
erratum
OpenAlex
Sujan Timilsina, S. Kara, Marie‐Agnès Jacques, Neha Potnis et autres
Microbiology Society journals contain high-quality research papers and topical review articles. We are a not-for-profit publisher and we support and invest in the microbiology community, to the benefit of everyone. This supports our principal goal to develop, expand and strengthen the networks …
us, tr, fr
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2023
article
OpenAlex
Manoj Choudhary, Gerald V. Minsavage, Erica M. Goss, Sujan Timilsina et autres
Xanthomonas spp. infect a wide range of annual and perennial plants. Bacterial blight in young seedlings of Eucalyptus spp. in Indonesia was originally identified as X. perforans. However, these strains failed to elicit a hypersensitive response (HR) on either tomatoes or peppers. …
us, Afrique du Sud
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