Roberto Magalhães Pinto

Phenotypic Switch From Atopic Dermatitis to Psoriasis During Dupilumab Therapy: A Real‐Life Experience From a Tertiary Referral Center

Alessandra Chiei Gallo, Gianluca Tavoletti, Davide Termini, Gianluca Avallone et autres

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Effectiveness of Dupilumab and Tralokinumab in Treating Nummular Eczema

Francesca Barei, Alessandra Chiei Gallo, Roberto Magalhães Pinto, Martina Zussino et autres

The data that support the findings of this study are available on request from the corresponding author. The data are not publicly available due to privacy or ethical restrictions.

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Effectiveness and safety of upadacitinib in patients with moderate-to-severe atopic dermatitis and prior inefficacy of T helper 2 biologics: a propensity score-matched study

Francesca Barei, Alessandra Chiei Gallo, Alessandra Narcisi, Ruggero Cascio Ingurgio et autres

BACKGROUND: Real-world data comparing patients with atopic dermatitis (AD) initially treated with upadacitinib vs. those previously treated with biologics or other Janus kinase inhibitors are limited. OBJECTIVES: To assess clinical outcomes over 52 weeks of treatment with upadacitinib and to compare patients …

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Use of Nasal Nitric Oxide to Compare Endoscopic Sinus Surgery Versus Dupilumab: An Exploratory Real-World Comparison

Daniel J. Lee, Giovanni Paoletti, Gaia Giulietti, Elysia Grose et autres

OBJECTIVE: To compare the outcomes of endoscopic sinus surgery (ESS) and dupilumab using nasal nitric oxide (nNO) as a biomarker of mucosal health, Lund-Kennedy endoscopy score (LKES), and Sino-Nasal Outcome Test-22 (SNOT-22). METHODS: A prospective observational cohort of chronic rhinosinusitis with nasal …

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Loop diuretic discontinuation in chronic heart failure patients: A retrospective study

Gonçalo Silva, Brenda Moura, Emília Moreira, Cláudia Camila Dias et autres

Introduction and Objectives: The use of loop diuretics is central in managing congestion in heart failure (HF), but their impact on prognosis remains unclear. In euvolemic patients, dose reduction is recommended, but there is no recommendation on their discontinuation. This study aims …

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Same-day discharge after elective percutaneous closure of patent foramen ovale

Catarina Martins da Costa, A F Amador, Roberto Magalhães Pinto, Bruno Bragança et autres

Percutaneous closure of the patent foramen ovale (PFO) is increasingly performed in specific patients with cryptogenic stroke or clinical evidence of a paradoxical embolism. This study was performed to determine the safety of same-day discharge (SDD) following such procedures. This is a …

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Unraveling the genetic background of individuals with a clinical familial hypercholesterolemia phenotype

Ana Margarida Medeiros, Ana Catarina Alves, Beatriz Miranda, Joana Rita Chora et autres

Familial hypercholesterolemia (FH) is a common genetic disorder of lipid metabolism caused by pathogenic/likely pathogenic variants in LDLR, APOB, and PCSK9 genes. Variants in FH-phenocopy genes (LDLRAP1, APOE, LIPA, ABCG5, and ABCG8), polygenic hypercholesterolemia, and hyperlipoprotein (a) [Lp(a)] can also mimic a …

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Wernicke encephalopathy and beriberi disease presenting as STEMI-equivalent

Miguel Martins Carvalho, T Proença, Ricardo Alves Pinto, Roberto Magalhães Pinto et autres

Thiamine deficiency is commonly associated with malnutrition, alcoholism and bariatric surgery. Thiamine deficiency can manifest in different ways, especially in developing countries: as peripheric neuropathy, as Wernicke encephalopathy or as beriberi disease. The authors present the case of a 72-year-old male, with …

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Total thyroidectomy in a patient awaiting heart transplant with amiodarone‐induced thyrotoxicosis: A case report

F Amador, Fernando Miguel Mendonça, Catarina da Costa, Marta Borges‐Canha et autres

Thyroid function may have a severe impact in cardiac function. Herein, we present the case report of a 53-year-old male patient awaiting heart transplant with amiodarone induced thyrotoxicosis that presented a marked improvement of his cardiac function after total thyroidectomy.

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Redefining the role of inotropes in advanced heart failure

Roberto Magalhães Pinto

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Effectiveness of Exercise-Based Cardiac Rehabilitation for Heart Transplant Recipients: A Systematic Review and Meta-Analysis

Rúben Costa, Emília Moreira, José Silva‐Cardoso, Luís Filipe Azevedo et autres

Background: Heart Transplant (HTx) is the ultimate chance of life for end stage Heart Failure (HF). Exercise training has consistently shown the potential to improve functional capacity in various chronic heart diseases. Still, the evidence in HTx recipients is scarcer. This study …

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Patient delay in acute myocardial infarction: a long journey still ahead

Charles Gabriel Formiga de Miranda Marques, António Cabrita, Paulo Maia Araújo, T Proença et autres

Abstract Background It is overly known that time delays in acute myocardial infarction (AMI) strongly influence its outcomes. Patient delay (PD) is repeatedly pointed out as the longer one in this context, as well as it is the less modifiable one by …

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