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Profil bibliographique

Li Xie

Informations fournies par OpenAlex. Research Africa ne déduit ni nationalité, ni poste, ni coordonnées personnelles.

39Publications signalées
1047Citations signalées
3Affiliations récentes

Les institutions déclarées

Les domaines associés

Evolution and Genetic DynamicsMicro and Nano RoboticsEvolutionary Game Theory and CooperationGene Regulatory Network AnalysisMolecular Communication and Nanonetworks

Les publications récentes

Accès ouvert 2026 article OpenAlex

Gut Microbiota in Pulmonary Arterial Hypertension: Murine Models and Human Microbial Signatures, Pathogenic Mechanisms, and Emerging Therapeutic Avenues

Yudan Qiu, Xiaojiang Lyu, Dashuang Zhang, Hong Liang Xu et autres

Pulmonary arterial hypertension (PAH) is a chronic, severe cardiopulmonary disease characterized by the progressive increase in pulmonary vascular resistance (PVR) because of the proliferation and fibrosis of the pulmonary arterioles. Although the disease originates in the pulmonary vasculature, it ultimately leads to …

cn (code pays fourni par la source)

2 citations Comprehensive physiology
2024 conference-abstract OpenAlex

Parking lot vehicle recognition system

Shenghua He, Li Xie, Yuanzhou Huang, Haoxiang Wang et autres

In modern cities, as the demand for transportation increases, the number of vehicles continues to rise, thereby increasing the demand for multi-level parking garages. Unlike traditional open-air parking lots, multi-level parking garages need to consider the weight of different vehicles and require …

mo (code pays fourni par la source)

0 citations
Accès ouvert 2023 preprint OpenAlex

A quantitative genetics framework for understanding the selection response of microbial communities

Li Xie, Alex E. Yuan, Wenying Shou

Abstract Heritability, a quantity that reflects the degree of resemblance between parent and offspring traits, is measured during plant and animal breeding because it predicts selection success during artificial selection of individuals. However, when whole microbial communities are under artificial selection to …

Afrique du Sud, us, gb (code pays fourni par la source)

7 citations bioRxiv (Cold Spring Harbor Laboratory)
Accès ouvert 2021 article OpenAlex

Steering ecological-evolutionary dynamics to improve artificial selection of microbial communities

Li Xie, Wenying Shou

Microbial communities often perform important functions that depend on inter-species interactions. To improve community function via artificial selection, one can repeatedly grow many communities to allow mutations to arise, and "reproduce" the highest-functioning communities by partitioning each into multiple offspring communities for …

Afrique du Sud, us, gb, es (code pays fourni par la source)

54 citations Nature Communications
Accès ouvert 2019 article OpenAlex

Simulations reveal challenges to artificial community selection and possible strategies for success

Li Xie, Alex E. Yuan, Wenying Shou

Multispecies microbial communities often display "community functions" arising from interactions of member species. Interactions are often difficult to decipher, making it challenging to design communities with desired functions. Alternatively, similar to artificial selection for individuals in agriculture and industry, one could repeatedly …

us (code pays fourni par la source)

75 citations PLoS Biology
Accès ouvert 2019 article OpenAlex

Uncovering and resolving challenges of quantitative modeling in a simplified community of interacting cells

Samuel F. M. Hart, Hanbing Mi, Robin Green, Li Xie et autres

Quantitative modeling is useful for predicting behaviors of a system and for rationally constructing or modifying the system. The predictive power of a model relies on accurate quantification of model parameters. Here, we illustrate challenges in parameter quantification and offer means to …

us (code pays fourni par la source)

50 citations PLoS Biology
Accès ouvert 2019 conference-paper OpenAlex

The Equipment Target Price Adjusting Model Based on Uncontrollable Technical Risk

Shengxiang Sun, Shuang Han, Li Xie

In view of the uncontrollable technical risk resulted in the actual cost is far more than the target price in the process of equipment development, the mode of existing incentive -constrained pricing cannot play an effective role, the equipment suppliers lose enthusiasm …

cn (code pays fourni par la source)

0 citations Proceedings of the 2019 International Conference on Economic Management and Cultural Industry (ICEMCI 2019)
Accès ouvert 2018 preprint OpenAlex

Resolving challenges in quantitative modeling of microbial community dynamics

Samuel F. M. Hart, Hanbing Mi, Robin Green, Li Xie et autres

Abstract Microbial communities can perform biochemical activities that monocultures cannot. Controlling communities requires an understanding of community dynamics. Here, we mathematically predict the growth rate of an engineered community consisting of two S. cerevisiae strains, each releasing a metabolite required and consumed …

us (code pays fourni par la source)

2 citations bioRxiv (Cold Spring Harbor Laboratory)
Accès ouvert 2018 preprint OpenAlex

Microscopy quantification of microbial birth and death dynamics

Samuel F. M. Hart, David Skelding, Adam James Waite, Justin C. Burton et autres

Abstract Microbes live in dynamic environments where nutrient concentrations fluctuate. Quantifying fitness (birth and death) in a wide range of environments is critical for understanding microbial evolution as well as ecological interactions where one species alters the fitness of another. Here, using …

us (code pays fourni par la source)

3 citations bioRxiv (Cold Spring Harbor Laboratory)

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