Stefania Trasarti

Pampiniform venous plexus thrombosis in a 37 years-old male patient with severe thrombocytosis: a multifactorial aetiology

Valeria Filipponi, M. Antonacci, Luisa Bizzoni, Mario Biglietto et autres

Atypical thrombosis occurs in unconventional anatomical sites such as splanchnic, renal, gonadal, and cerebral venous vessels [1] . Genetic factors, as inherited thrombophilia could increase the risk of atypical thrombosis. Likewise, acquired disease, as cancer, autoimmune diseases (e.g. systemic lupus erythematosus and …

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Exploring the dynamics of FGF23 in patients with Hereditary Hemochromatosis type I following iron depletive treatment: a pilot study

Luciano Colangelo, Sergio Terracina, Chiara Sonato, Viviana De Martino et autres

PURPOSE: Anemia, inflammation and iron deficiency are linked to Fibroblast growth factor 23 (FGF23). Aim of this study was to explore the dynamics of FGF23 in Hereditary Hemochromatosis type-I (HH1). METHODS: Twenty-six consecutive patients with genetically confirmed and uncomplicated HH1 and nineteen …

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Erratum in: Exploring the administrative burden faced by hematologists: a comprehensive study in Italy

Davide Petruzzelli, Marco Vignetti, Stefania Trasarti, Paolo Sportoletti et autres

In the article “Exploring the administrative burden faced by hematologists: a comprehensive study in Italy” (1), which appeared in Volume 11, Issue 1 of Global and Regional Health Technology Assessment, the affiliation 1 for authors Davide Petruzzelli and Silvia Della Torre was …

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An Unusual Case of Multifactorial Hemolytic Anemia: A Complex Interaction Between Genetic and Autoimmune Factors

Mario Biglietto, Giusy Peluso, Cristina Luise, Diletta Tripi et autres

Hemolytic anemias (HAs) encompasses a heterogeneous group of disorders with either congenital or acquired etiologies. We present a complex case of a 27-year-old woman with hemolytic anemia of multifactorial origin, involving both inherited RBC membrane defects and multiple autoimmune comorbidities. Genetic testing …

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Exploring the administrative burden faced by hematologists: a comprehensive study in Italy

Davide Petruzzelli, Marco Vignetti, Stefania Trasarti, Paolo Sportoletti et autres

Background: Administrative burdens have been identified as a major issue impacting patient care, professional practice, and the overall efficiency of healthcare systems. The aim of this study is to assess the administrative burden faced by Italian hematologists. Methods: A cross-sectional survey that …

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Gamma heavy chain disease associated with T-cell large granular lymphocyte lymphoproliferative disorder: case report and literature review.

Maria Laura Bisegna, Maria Assunta Limongiello, Stefano Fiori, Maria Stefania De Propris et autres

Heavy chain diseases are rare B-cell neoplasms consisting of the production of a monoclonal immunoglobulin composed of the only heavy chain without corresponding light chains. It is a rare adult disease that may involve several sites with a variable clinical course. It …

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Multiple Cutaneous Manifestations in ANCA-Positive Eosinophilic Granulomatosis with Polyangiitis before and after Biologic Therapy: Clinical and Histopathologic Characterization of a Paradigmatic Case

Giorgia Carnicelli, Alvise Sernicola, Vito Gomes, Giulia Cundari et autres

Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare immune-mediated vasculitis associated with anti-neutrophil cytoplasmic antibodies (ANCAs). Having systemic and possibly severe involvement, a prompt recognition of its clinical features is crucial to achieve favorable patient outcomes. Although cutaneous manifestations represent key elements, …

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Abdominal Lymphadenopathy: Hypothesize Cat-Scratch Disease and Avoid Abdominal Excisional Biopsy

Valeria Filipponi, Stefania Trasarti, Francesca Maccioni, Maddalena Zippi et autres

The finding of lymphadenopathy is usually the consequence of a benign infection, although a neoplastic origin must always be excluded. Through a careful anamnesis, physical examination, and serological tests several differential diagnoses are frequently possible. Nevertheless, sometimes an excisional biopsy of superficial …

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Lymphadenopathies before and during the Pandemic COVID-19: Increasing Incidence of Metastases from Solid Tumors

Stefania Trasarti, Raffaele Troiano, Mario Biglietto, Silvia Sorella et autres

Since December 2019, the world has experienced a pandemic caused by SARS-CoV-2, a virus which spread throughout the world. Anti-COVID19 measures were applied to limit the spread of the infection, affecting normal clinical practice. In 2020, studies on the possible impact of …

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Clinical and Prognostic Features of Essential Thrombocythemia: Comparison of 2001 WHO Versus 2008/2016 WHO Criteria in a Large Single-center Cohort

Sofia Chiatamone Ranieri, Maria Antonietta Arleo, Stefania Trasarti, Luisa Bizzoni et autres

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Aplastic Anemia and Good Syndrome in a Heavily Treated Stage IV Thymoma Patient: A Case Report and Review of the Literature

Sofia Chiatamone Ranieri, Stefania Trasarti, Maria Antonietta Arleo, Luisa Bizzoni et autres

Thymoma is an uncommon slowly growing neoplasm. It usually presents with paraneoplastic syndromes including the immunodeficiency syndrome called Good syndrome and hematological disorders. Pure red cell aplasia is a well-recognized complication of thymoma, and aplastic anemia is very rare in association with …

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Clinical and Prognostic Features of Essential Thrombocythemia: Comparison of Who 2001 Versus Who 2008/2016 Criteria in a Large Single Center Cohort

Sofia Chiatamone Ricci, Maria Antonietta Arleo, Stefania Trasarti, Cristina Santoro et autres

Abstract According to the World Health Organization (WHO) 2008/2016 criteria for classification of myeloid neoplasms, a platelet (PLT) count ≥ 450X109/l, thus reduced from the previous WHO 2001 level ≥ 600 x 109/l, was considered the new PLT threshold for the diagnosis …

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