George Tolis

P129. Durability of Internal Mammary Artery Grafts in Cardiac Surgery Patients with Prior Mediastinal Radiation

Adham Makarem, Emmanuel Odekunle, Patrick Udeh, Zoe Laddis et autres

RF26. Impact of Unplanned Coronary Interventions on Morbidity and Mortality in Aortic Root Replacement: A 20-Year, Multicenter Retrospective Study

Ajami Gikandi, Boateng Kubi, Jack Guiry, Ruby Singh et autres

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Long-Term Outcomes of Repeated Transcatheter Aortic Valve Replacement vs Transcatheter Aortic Valve Replacement Explantation: A Nationwide Analysis

Thais Faggion Vinholo, Jake A. Awtry, Mansoo Cho, Philip M. Allen et autres

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Randomized Controlled: Trial of New Oral Anticoagulants Versus Warfarin for Postcardiac Surgery Atrial Fibrillation

Philicia Moonsamy, Yunong Zhao, Adham Makarem, Dane C. Paneitz et autres

OBJECTIVE: To determine whether anticoagulation for new onset atrial fibrillation (AF) with rivaroxaban decreases length of stay compared with warfarin. SUMMARY OF BACKGROUND DATA: Direct Oral Anticoagulants (DOACs) have been shown to be noninferior to warfarin for stroke prevention in nonsurgical patients …

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Novel Bioprostheses: Is 5 Years Still Within the Honeymoon Phase?

George Tolis

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Across 73 meta-analyses mortality improvements are uncommon with newer interventions in adult cardiac surgery

Austin J. Parish, George Tolis, John P. A. Ioannidis

OBJECTIVES: We aimed to assess how often randomized controlled trials (RCTs) in adult cardiac surgery found significant mortality benefits for newer interventions vs older ones, whether observed treatment effect estimates changed over time and whether RCTs and nonrandomized observational studies gave similar …

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Are there mortality improvements with newer interventions in adult cardiac surgery? Evidence from 73 meta-analyses

Austin J. Parish, George Tolis, John P. A. Ioannidis

ABSTRACT Background In the last two decades, many new interventions have been introduced with the ultimate goal of improving overall postoperative outcomes after cardiac operations in adults. We aimed to assess how often randomized controlled trials (RCTs) in adult cardiac surgery found …

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Outcomes of surgical valve replacements for radiation-induced valvulopathy

Annie R. Abruzzo, Siobhan McGurk, George Tolis, Sary F. Aranki et autres

Objective Patients with cancer who receive radiation therapy to the thorax often develop radiation-induced heart disease (RIHD) decades later. Previous chest radiation is associated with elevated perioperative risk of complications and mortality after cardiac surgery. Whether the type of valve (mechanical vs …

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Performance of left internal thoracic artery-left anterior descending artery anastomosis by residents versus attendings and coronary artery bypass grafting outcomes

Ajami Gikandi, Eileen M. Stock, Ellen J. Dematt, Sameer A Hirji et autres

OBJECTIVES: Performance of a technically sound left internal thoracic artery to left anterior descending artery (LITA-LAD) anastomosis during coronary artery bypass grafting (CABG) is critically important. We used prospectively collected data from the multicentre, randomized REGROUP (Randomized Endograft Vein Perspective) trial to …

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Mechanical Complications of Myocardial Infarction

Travis D. Hull, George Tolis

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Recruited macrophages elicit atrial fibrillation

Maarten Hulsmans, Maximilian J. Schloss, I‐Hsiu Lee, Aneesh C. Bapat et autres

Atrial fibrillation disrupts contraction of the atria, leading to stroke and heart failure. We deciphered how immune and stromal cells contribute to atrial fibrillation. Single-cell transcriptomes from human atria documented inflammatory monocyte and SPP1 + macrophage expansion in atrial fibrillation. Combining hypertension, …

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Operative Teaching of Coronary Bypass and Need for Repeat Catheterization: Does it Matter Who is Sewing?

George Tolis, Laura M. Piechura, Navyatha Mohan, Eugene V. Pomerantsev et autres

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