Enhua Xiao

Copper-cysteamine nanoparticles reprogram mitochondrial fusion to potentiate sonodynamic therapy for hepatocellular carcinoma

Minping Zhang, Meitao Liu, Yu Cheng, Jiayi Liu et autres

Hepatocellular carcinoma (HCC) remains a formidable therapeutic challenge due to its high recurrence rate and limited therapeutic options, especially in advanced stages. Sonodynamic therapy (SDT) has emerged as a promising non-invasive approach with deep-tissue penetration capabilities. However, its efficacy is hindered by …

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A Near‐Field Coupling Array Enables Parallel Imaging and SNR Gain in MRI (Adv. Sci. 37/2025)

Zhiguang Mo, Shao Che, Feng Du, Enhua Xiao et autres

Near-Field Coupling Array for Wireless MRI RF Coils In article number 2503481, Ye Li and co-workers highlight a novel wireless radiofrequency (RF) reception architecture based on metasurfaces, termed the near-field coupling array (NFCA), designed to enhance image quality of magnetic resonance imaging …

The Combined Use of Dual-Tuned 1H/2H Coils and Metamaterial Coils for Enhanced UHF Imaging Performance in Mice

Ping He, Enhua Xiao, Nan Li, Feng Du et autres

Motivation: Hydrogen-deuterium dual-nuclear imaging provides structural and metabolic data, but sensitivity and abundance differences can limit imaging quality. Upgrading the coil structure is necessary to enhance both hydrogen and deuterium imaging performance. Goal(s): The goal of this study is to improve hydrogen-deuterium …

A Novel Self-Tuned and Self-Decoupled Wireless Prostate Array for Enhanced Imaging Resolution and SNR at 3T MRI

Shahzeb Hayat, Enhua Xiao, Wenhao Liao, Zhiguang Mo et autres

Motivation: Prostate coils have become more efficient due to advancements in imaging. Currently, prostate coils struggle with tuning, matching, sensitivity, resolution, and SNR, while a novel 5-channel wireless array offers self-tuning, self-decoupling, and enhanced SNR. Goal(s): This study aims to develop a …

High-Impedance Wireless Coax Coil for Enhanced Wearable MRI Applications

Enhua Xiao, Shahzeb Hayat, Wenhao Liao, Peiyu He et autres

Motivation: Conventional MRI coils are bulky and rigid, limiting comfort and signal in curved areas, creating demand for flexible, wireless alternatives. Goal(s): Enhance signal acquisition in anatomically complex regions while improving patient comfort and reducing design complexity and cost. Approach: We designed …

Self-decoupled Wireless array for SNR enhancement in 5T MRI

Wenhao Liao, Enhua Xiao, Wei William Cao, Du Feng et autres

Motivation: To enhance SNR for imaging complex human structures and to address the coupling issues in wireless surface coil arrays. Goal(s): In order to achieve uniform SNR gain by self-decoupled wireless array, which can significantly improve the SNR performance. Approach: In this …

A Wireless Endorectal Coil Based on a Near-Field Coupling Array System for Prostate MRI

Zhiguang Mo, Enhua Xiao, Shahzeb Hayat, Nan Li et autres

Motivation: In prostate MRI, wired endorectal coils are commonly used to compensate for the SNR limitations of surface coils. However, due to components like preamplifier circuits and cables, these wired coils are not cost-effective for single-use applications. Goal(s): In this study, we …

Wireless array for SNR enhancement in small animal MRI at 5T

Wenhao Liao, Enhua Xiao, Peiyu He, Wei William Cao et autres

Motivation: Clinical MRI scanners lack sufficient SNR for high-resolution small animal imaging, limiting research on diseases. Goal(s): Design a compact, wireless array to improve SNR and enable high-resolution imaging in small animal MRI at 5T. Approach: In this study, we made a …

Radiation-Free Dental Imaging: High-Resolution MRI with a Wireless Braces-Shaped Coil——Try to beat CBCT

Enhua Xiao, Shahzeb Hayat, Wenhao Liao, Peiyu He et autres

Motivation: MRI offers a potential alternative to CBCT, reducing radiation exposure and enhancing soft tissue contrast. Goal(s): Develop a braces-shaped wireless coil for high-resolution, radiation-free imaging of upper and lower teeth. Approach: We designed a braces-shaped wireless coil for intraoral use, enhancing …

A Near‐Field Coupling Array Enables Parallel Imaging and SNR Gain in MRI

Zhiguang Mo, Shao Che, Feng Du, Enhua Xiao et autres

Wireless radiofrequency (RF) coils based on metasurfaces hold great promise for improving clinical magnetic resonance imaging (MRI) workflows by eliminating the need for cable connections to the patient bed and simplifying coil structures. A fundamental requirement for their clinical adoption is the …

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Deep Learning Model Based on Dual-energy CT for Assessing Cervical Lymph Node Metastasis in Oral Squamous Cell Carcinoma

Yiming Qi, Lijie Zhang, Yu Wang, Xiaohui Duan et autres

BACKGROUND: Accurate detection of lymph node metastasis (LNM) in oral squamous cell carcinoma (OSCC) is crucial for treatment planning. This study developed a deep learning model using dual-energy CT to improve LNM detection. METHODS: Preoperative dual-energy CT images (Iodine Map, Fat Map, …

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Multi-parameter magnetic resonance imaging of zebularine in liver fibrosis treatment and calcineurin/ NFAT3 mechanism

Shiyi Lyu, Wang Xiao, Yanjing Chen, Yeyu Cai et autres

BACKGROUND Hepatic stellate cell (HSC) activation is key to liver fibrosis. Targeting DNA methylation shows promise. Zebularine, a methylation inhibitor, may suppress HSC activation via the calcineurin (CaN)/NFAT3 pathway. Magnetic resonance imaging (MRI) is a noninvasive tool for evaluating liver fibrosis evaluation …

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