Stefano Scoglio

Klamath Lake Aphanizomenon Flos-Aquae: Wild-Harvesting, Extracts and Benefits

Stefano Scoglio, Gabriel Dylan Scoglio

This chapter examines Aphanizomenon flos-aquae (AFA) from Oregon’s Klamath Lake, emphasizing its nutritional richness and health benefits. Thriving in a unique volcanic ecosystem, this wild-harvested cyanobacterium is a powerhouse of nutrients, making it a prime focus in the health supplement domain. The …

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Positive Impacts of Aphanizomenon Flos Aquae Extract on Obesity-Related Dysmetabolism in Mice with Diet-Induced Obesity

Simona Terzo, Pasquale Calvi, Marta Giardina, G. Gallizzi et autres

, an Aphanizomenon flos aquae (AFA) extract, to counteract metabolic dysfunctions due to a high fat diet (HFD) or to accelerate their reversion induced by switching an HFD to a normocaloric diet in mice with diet-induced obesity. A group of HFD mice …

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Aphanizomenon flos-aquae (AFA) Extract Prevents Neurodegeneration in the HFD Mouse Model by Modulating Astrocytes and Microglia Activation

Giacoma Galizzi, Irene Deidda, Antonella Amato, Pasquale Calvi et autres

Obesity and related metabolic dysfunctions are associated with neurodegenerative diseases, such as Alzheimer’s disease. Aphanizomenon flos-aquae (AFA) is a cyanobacterium considered a suitable supplement for its nutritional profile and beneficial properties. The potential neuroprotective effect of an AFA extract, commercialized as KlamExtra®, …

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Spasmolytic Effects of Aphanizomenon Flos Aquae (AFA) Extract on the Human Colon Contractility

Antonella Amato, Simona Terzo, Pierenrico Marchesa, A. Maffongelli et autres

The blue-green algae Aphanizomenon flos aquae (AFA), rich in beneficial nutrients, exerts various beneficial effects, acting in different organs including the gut. Klamin® is an AFA extract particularly rich in β-PEA, a trace-amine considered a neuromodulator in the central nervous system. To …

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AphaMax®, an Aphanizomenon Flos-Aquae Aqueous Extract, Exerts Intestinal Protective Effects in Experimental Colitis in Rats

Maria Grazia Zizzo, G Caldara, Annalisa Bellanca, Domenico Nuzzo et autres

Background: Aphanizomenon flos-aquae (AFA) is a unicellular cyanobacterium considered to be a “superfood” for its complete nutritional profile and beneficial properties. We investigated possible beneficial effects of an AFA extract, commercialized as AphaMax®, containing concentrated amount of phycocyanins and phytochrome, in 2,4 …

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Heat-Resistant Aphanizomenon flos-aquae (AFA) Extract (Klamin®) as a Functional Ingredient in Food Strategy for Prevention of Oxidative Stress

Domenico Nuzzo, Marco Contardi, Despoina Kossyvaki, Pasquale Picone et autres

Microalgae are generally considered an excellent source of vitamins, minerals, and bioactive molecules that make them suitable to be introduced in cosmetics, pharmaceuticals, and food industries. Aphanizomenon flos-aquae (AFA), an edible microalga, contains numerous biomolecules potentially able to prevent some pathologies including …

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Complementary Treatment of Mood Disturbances in Terminally Ill Oncological Patients with the Aphanizomenon Flos Aquae Extract Klamin®

Stefano Scoglio

Crimson is an Open-access academic publisher has a vision to establish Open Science platform that seeks to provide equal opportunity. Our mission is to offer quality editorial services, significant resources into technology innovation, freely accessible, discoverable scientific information, and high-quality publications.

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Microcystins in water and in microalgae

Stefano Scoglio

Microcystins have been the subject of increasingly alarming popular and scientific articles, which have taken as their unquestionable foundation the provisional Guideline of 1 μg/L established by the WHO Panel on microcystins levels in water, and mechanically translated by the Oregon government …

Effects of the Aphanizomenon flos-aquae Extract (Klamin®) on a Neurodegeneration Cellular Model

Domenico Nuzzo, Giovanni Presti, Pasquale Picone, Giacoma Galizzi et autres

Cyanobacteria have been recognized as a source of bioactive molecules to be employed in nutraceuticals, pharmaceuticals, and functional foods. An extract of Aphanizomenon flos-aquae (AFA), commercialized as Klamin®, was subjected to chemical analysis to determine its compounds. The AFA extract Klamin® resulted …

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The Effect of Experimental Supplementation with the Klamath Algae Extract Klamin on Attention-Deficit/Hyperactivity Disorder

Maurizio Cremonte, Davide Sisti, Ilaria Maraucci, Simona Giribone et autres

Attention-deficit/hyperactivity disorder (ADHD) is a chronic neurobiological condition with onset in childhood. The disorder is characterized by inattention, impulsivity, and/or motor hyperactivity, which often affect the development and social integration of affected subjects. Phenylethylamine (PEA), naturally contained in the Klamath Lake microalgae …

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Influence of Aphanizomenon flos-aquae and two of its extracts on growth ability and antimicrobial properties of Lactobacillus acidophilus DDS-1

Raffaella Campana, Verônica Martinelli, Stefano Scoglio, Evelin Colombo et autres

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Inhibitory effects ofAphanizomenon flos-aquaeconstituents on human UDP-glucose dehydrogenase activity

Stefano Scoglio, Valeria Lo Curcio, Simona Catalani, Francesco Palma et autres

OBJECTIVE: The purpose of this study was to investigate the in vitro inhibitory effects of the edible microalga Aphanizomenon flos-aquae (AFA) on human UDP-α-d-glucose 6-dehydrogenase (UGDH) activity, a cytosolic enzyme involved both in tumor progression and in phytochemical bioavailability. METHODS: Both the …

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