Accès ouvert
2025
article
OpenAlex
Takuya Kumagai, Ayano Saito, Kazuhisa Yoshizawa, Masahiro Takeshima et autres
INTRODUCTION: Distal renal tubular acidosis (dRTA) is characterized by impaired acidification in the distal tubules and may be associated with genetic factors, such as ATP6V0A4 variants. The role of clozapine in triggering dRTA, particularly in individuals with underlying genetic susceptibility, remains poorly …
jp
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Nana Shibata, Kazuhisa Yoshizawa, Masahiro Takeshima, Shingo Kitamura et autres
Aim: To investigate the relationship between the prescription of novel hypnotics (melatonin receptor agonists [MRAs] and orexin receptor antagonists [ORAs]) and the risk of hip fractures in a large cohort of Japanese patients. Methods: In this retrospective study, we analyzed data from …
jp
(code pays fourni par la source)
Accès ouvert
2025
review
OpenAlex
Taku Maruki, Masahiro Takeshima, Kazuhisa Yoshizawa, Naoaki Otsuka et autres
Combination therapy with antidepressants and sleep medications is a promising candidate treatment for major depressive disorder (MDD) with insomnia. This systematic review and meta-analysis examined the efficacy and safety of combination therapy with antidepressants and sleep medication for treating MDD with insomnia …
jp
(code pays fourni par la source)
Accès ouvert
2025
conference-abstract
OpenAlex
Masahiro Takeshima, Kazuhisa Yoshizawa, Masaya Ogasawara, Yu Itoh et autres
Abstract Background Long-term prescriptions of hypnotics is a worldwide problem. In Japan, medical fee reductions were implemented thrice between 2012 and 2018 to promote the appropriate use of hypnotics (2012 and 2014 for polypharmacy of three or more hypnotics, 2018 for long-term …
jp
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Munehiro Komatsu, Masahiro Takeshima, Kazuhisa Yoshizawa, Masaya Ogasawara et autres
Introduction: Hypnotic polypharmacy and its long-term prescriptions constitute the inappropriate use of hypnotics. However, the relationship between hypnotic polypharmacy and prolonged prescriptions remains unclear. This study aimed to elucidate the association between hypnotic polypharmacy and the duration of hypnotic prescriptions. Methods: This …
jp
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Keisuke Irinaka, Yu Itoh, Kazuhisa Yoshizawa, Masaya Ogasawara et autres
Tardive dyskinesia and dystonia are intractable extrapyramidal symptoms caused by the blockade of dopamine receptors by antipsychotic drugs. In addition to the reduction or discontinuation of the causative drug, valbenazine for tardive dyskinesia and botulinum toxin for tardive dystonia have been reported …
jp
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Masahiro Takeshima, Kazuhisa Yoshizawa, Masaya Ogasawara, Mizuki Kudo et autres
Psychotropic polypharmacy is a significant health concern, particularly among older adults, due to adverse event risks. 1 In Japan, policy interventions aimed at correcting psychotropic polypharmacy have been implemented (Table S1). 2 The 2012 policy intervention reduced psychiatry-related reimbursement for prescribing ≥3 …
jp
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Masahiro Takeshima, Kazuhisa Yoshizawa, Masaya Ogasawara, Mizuki Kudo et autres
Introduction: Guidelines for various psychiatric disorders recommend short-term use of benzodiazepine anxiolytic monotherapy in few cases. Contrarily, benzodiazepine anxiolytic polypharmacy (BAP) is not recommended in any case. However, BAP is often used in real world. Therefore, this study aimed to determine the …
jp
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Mizuki Kudo, Naoko Ayabe, Masahiro Takeshima, Masaya Ogasawara et autres
Previous studies on sleep state misperception have objectively evaluated sleep status in special environments using polysomnography. There is a paucity of data from studies that evaluated habitual sleep status in home environments. The present study aimed to investigate sleep state misperception in …
jp
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Masahiro Takeshima, Kazuhisa Yoshizawa, Masaya Ogasawara, Mizuki Kudo et autres
Importance: Although insomnia guidelines recommend the use of several individual hypnotics, the most useful hypnotic for treating insomnia in a clinical setting remains unclear. Objective: To determine which guideline-recommended hypnotics have lower risks of monotherapy failure and which hypnotics have a higher …
jp
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Masahiro Takeshima, Akise Umakoshi, Yuki Omori, Kazuhisa Yoshizawa et autres
RATIONALE: The efficacy and safety of antidepressant augmentation therapy with aripiprazole (AATA) has been established; however, the ongoing effects of continuing aripiprazole after remission remain unclear because no studies have examined this issue. OBJECTIVES: We aimed to explore the effect of AATA …
jp
(code pays fourni par la source)
Accès ouvert
2023
article
OpenAlex
Masaya Ogasawara, Masahiro Takeshima, Shumpei Kosaka, Aya Imanishi et autres
Purpose: Sleep-tracking devices have performed well in recent studies that evaluated their use in healthy adults by comparing them with the gold standard sleep assessment technique, polysomnography (PSG). These devices have not been validated for use in patients with psychiatric disorders. Therefore, …
jp
(code pays fourni par la source)