Qingyun Yang

Self-sustaining ROS-responsive hydrogel enabled delivery of PROTAC/Ce6 nanoparticles via PDT-Epigenetic protein degradation to amplify pyroptosis for enhanced cancer immunotherapy

Liming Gong, Jing Feng, Liqing Chen, Mong-Hsiu Song et autres

cn (code pays fourni par la source)

Contour-Constrained Deformable Registration with Parameter Characterization for Head and Neck Surgical Guidance

Qingyun Yang, Jon S. Heiselman, Ayberk Acar, Morgan J. Ringel et autres

With 890,000 annual new cases globally, head and neck squamous cell carcinoma has one of the highest recurrence rates among solid malignancies. Although frozen section analysis is the standard of care for intraoperative margin assessment, accurately relocating detected positive margins on the …

Cationic DVDMS liposomes in a thermosensitive gel for enhanced intrarectal photodynamic therapy of colorectal cancer

Xiaoliang Gong, Liqing Chen, Chunxi Liu, Lundang Guo et autres

cn (code pays fourni par la source)

Modular design for drug delivery across hierarchical gastrointestinal barriers: From materials to systems

Yaxin Chen, Qingyun Yang, Jian Yang, Jiquan Zhang

Drug delivery to the gastrointestinal (GI) tract necessitates overcoming multi-level physiological barriers from organ to cellular levels, which exhibit significant heterogeneity under pathological conditions. Conventional delivery strategies, constrained by single-function capabilities, struggle to achieve cross-scale coordination, severely limiting therapeutic efficacy. Modular design …

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Development and Evaluation of a Phospholipid Complex-Loaded SMEDDS for Enhanced Oral Delivery of H007, a Novel Anti-Hyperlipidemic Drug

Chaoying Liu, Lundang Guo, Lie Chen, Xiaoliang Gong et autres

Background: H007 is a novel selective AMP-activated protein kinase (AMPK) activator with demonstrated efficacy against hyperlipidemia; however, its oral bioavailability is limited by poor solubility and low intestinal permeability. This study aimed to develop a self-microemulsifying drug delivery system (SMEDDS) incorporating a …

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Tailored core - shell sulfonated carbon dots with functional shells for enhanced lubrication and anticorrosion

Ting Ying, Long Chen, Yongtao Zhang, Xia Wang et autres

cn, jp (code pays fourni par la source)

Design of lightweight human pose estimation network for rehabilitation training

Qingyun Yang, Gaigai Zhang

Given the resource constraints of terminal devices, existing pose estimation networks, characterised by high computational complexity, struggle to satisfy the simultaneous demands of real-time performance and accuracy in rehabilitation training.Therefore, this paper proposes a lightweight human pose estimation network specifically designed for …

Hydrogen sulfide revisited: a stealthy ally in the unseen war against cardiovascular disease

Rui Liang, Yang Li, Qingyun Yang, Jiaxin Duan et autres

cn (code pays fourni par la source)

Molecularly-engineered benzazole derived protic ionic liquids enable ultra-low wear and superior corrosion protection

Xia Wang, Qingzhao Cai, Yongtao Zhang, Ting Ying et autres

cn, jp (code pays fourni par la source)

Augmented Reality-Based Guidance with Deformable Registration in Head and Neck Tumor Resection

Qingyun Yang, Fangjie Li, Jiayi Xu, Zixuan Liu et autres

us (code pays fourni par la source)

High‐Entropy‐Based Micro‐Doping Enables High‐Energy‐Density and Stable Layered Sodium Oxide Cathodes

Qingyun Yang, Zhiliang Xiu, Wei Zhang, Yu An et autres

Abstract Transition metal layered oxides are regarded as commercially viable cathode materials for sodium ion batteries (SIBs), but the inadequate rate capability and cyclability significantly impede their practical application. Here, a high‐entropy‐based micro‐doping strategy has been proposed to prepare an O3‐type Na …

cn (code pays fourni par la source)

Nonrigid alignment of en bloc tissue specimen to resection bed to enhance correspondence for re-resection guidance

Qingyun Yang, Ayberk Acar, Morgan J. Ringel, Jon S. Heiselman et autres

With approximately 890,000 new cases annually, head and neck squamous cell carcinoma has one of the highest recurrence rates among solid malignancies. Frozen section analysis is the standard of care for intraoperative margin assessment, yet accurately relocating detected positive margins on the …

us (code pays fourni par la source)