Reiji Fukano

Diplotype analysis of NUDT15 using digital PCR in pediatric acute lymphoblastic leukemia

Youji Iida, Reiji Fukano, Takuya Ichimura, Sachiyo Kamimura et autres

Acute lymphoblastic leukemia (ALL) is the most common form of pediatric leukemia in Japan and presents significant treatment challenges owing to variable patient sensitivity to the key therapeutic agent, 6-mercaptopurine. This variability is often linked to genetic differences, particularly variants of NUDT15 …

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QUALITATIVE AND QUANTITATIVE MINIMAL DISEASE MEASUREMENT IN ALK-POSITIVE ANAPLASTIC LARGE CELL LYMPHOMA: EFFICACY OF INTERNATIONAL QUALITY CONTROL AND EVENT-FREE SURVIVAL ACCORDING TO DIFFERENT MINIMAL DISSEMINATED DISEASE CUT-OFFS

Christine Damm‐Welk, Cathy Quelen, Laurence Lamant, Gaia Martire et autres

INTER-PLATFORM CONCORDANCE OF DIGITAL PCR-BASED MINIMAL DISSEMINATED DISEASE QUANTIFICATION IN PEDIATRIC ALK-POSITIVE ANAPLASTIC LARGE CELL LYMPHOMA

Reiji Fukano, Yuka Iijima‐Yamashita, Akiko Moriya Saito, Tetsuya Takimoto et autres

Acute effects of peripherally administered nicotine on food intake via the central anorectic peptide nesfatin-1/nucleobindin-2 in adult male rats

Reiko Saito, Yukiyo Yamamoto, Reiji Fukano, Masatomo Mori et autres

Acute/chronic exposure to nicotine modulates feeding behavior in experimental animals and humans. However, how nicotine modulates food intake remains unclear. This study examined the acute effects of the peripheral administration of nicotine on food intake in adult male rats, focusing on the …

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Prognostic Impact of Minimal Disseminated Disease By Digital PCR for Pediatric ALK-Positive Anaplastic Large Cell Lymphoma

Reiji Fukano, Yuka Iijima‐Yamashita, Hideto Iwafuchi, Atsuko Nakazawa et autres

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Abstract 9361: Interleukin-33 System as Potential Biomarker and Therapeutic Target in Kawasaki Disease

Seigo Okada, Hiroki Yasudo, Yuji Ohnishi, Chie Matsuguma et autres

Introduction: Kawasaki disease (KD) is an acute, self-limiting, febrile systemic vasculitis of unknown cause associated with the development of coronary artery lesions (CALs) during childhood. Damage-associated molecular patterns (DAMPs) from cell death and oxidative stress have been shown to be involved in …

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Interleukin-33/ST2 Axis as Potential Biomarker and Therapeutic Target in Kawasaki Disease

Seigo Okada, Hiroki Yasudo, Yuji Ohnishi, Chie Matsuguma et autres

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Histological characteristics of matrix metalloproteinase‐9 and tissue inhibitor of metalloproteinases‐1 in asthmatic murine model during A(H1N1)pdm09 infection

Sasagu Kimura, Hiroki Yasudo, Atsunori Oga, Reiji Fukano et autres

Pandemic influenza virus A(H1N1)pdm09 infection occurred in healthy children and young adults, but asthmatic patients presented more rapid progression of respiratory distress and plastic bronchitis. To investigate the pathogenesis of worsening respiratory symptoms after A(H1N1)pdm09 infection, we focused on matrix metalloproteinase-9 (MMP-9) …

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Safety and Feasibility of Infliximab Therapy in Children With Kawasaki Disease Who Received Live Vaccinations

Yuji Ohnishi, Seigo Okada, Akiko Kawakami-Miyake, Takashi Furuta et autres

BACKGROUND: Kawasaki disease (KD) is an acute and febrile systemic vasculitis that occurs during childhood. Infliximab (IFX) is a chimeric monoclonal antibody that binds to tumor necrosis factor-α. Although IFX therapy is a useful option for refractory KD, vaccine-associated infections may develop …

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Body weight and body composition among Japanese childhood leukemia/lymphoma survivors

Hideki Nakayama, Maiko Noguchi, Reiji Fukano, Tamaki Ueda et autres

Purpose: The study aimed to determine the body composition of Japanese adult survivors with childhood cancer. Methods: Between August 2018 and September 2019, we recruited adults aged ≥18 years who had childhood leukemia/lymphoma. Blood sampling, body composition measurement by bioelectrical impedance analysis …

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