Cristian Gherman

MicroRNAs in Cutaneous Melanoma: Biological Roles, Clinical Utility, and Future Directions

Adrian Ilie Pascu, Maximilian-Vlad Muntean, Cristian Gherman, Vlad Alexandru Gâta et autres

Cutaneous melanoma remains a malignancy with substantial metastatic potential, and conventional diagnostic and surveillance tools such as biopsy and imaging have recognized limitations in sensitivity, specificity, and invasiveness. Circulating microRNAs (miRNAs) have emerged as promising non-invasive biomarkers because of their stability in …

ro (code pays fourni par la source)

Artificial Intelligence and Esthetics: Redefining Precision and Beauty in Plastic Surgery

Dinu Iuliu Dumitraşcu, Stefan Lucian Popa, Victor Incze, Darius-Stefan Amarie et autres

Artificial intelligence (AI) is increasingly reshaping esthetic and reconstructive plastic surgery by improving measurement accuracy, treatment planning, and prediction of surgical outcomes. This article provides a scientific overview of current AI applications, including automated image analysis, machine-learning-based outcome forecasting, and generative models …

ro (code pays fourni par la source)

Non-Infectious Causes for Elevated Procalcitonin

Stefan Lucian Popa, Victor Incze, Abdulrahman Ismaiel, Teodora Surdea-Blaga et autres

Background and Objectives: Procalcitonin (PCT) is widely used to support the diagnosis of bacterial infection and sepsis, yet clinically relevant elevations also occur in multiple non-infectious conditions. This systematic review aimed to synthesize human evidence on non-infectious causes of elevated PCT and …

ro (code pays fourni par la source)

Molecular Mechanisms, Dynamic Lesions, and Therapeutic Targets in Intestinal Ischemia–Reperfusion Injury: A Systematic Review

Julia Marton, Răzvan Alexandru Ciocan, Ioana Bâldea, Luciana-Mădălina Gherman et autres

Intestinal ischemia-reperfusion injury (IRI) represents a major cause of morbidity and mortality in abdominal surgery, trauma, and intestinal transplantation. The pathophysiological process involves a biphasic cascade that begins with ischemic hypoxia and progresses to amplified cellular and molecular injury upon reperfusion. This …

ro (code pays fourni par la source)

Non-Infectious Causes for Elevated Procalcitonin

Stefan Lucian Popa, Victor Incze, Abrulrahman Ismaiel, Teodora Surdea-Blaga et autres

ro (code pays fourni par la source)

The Role of the Gut Microbiota in Vascular Physiology and Health

Maria Adriana Neag, Liviu-Ștefan Moacă, Andrada-Larisa Deac, Dan Claudiu Măgureanu et autres

Cardiovascular diseases (CVD) are the leading cause of global morbidity and mortality. There are many well-known risk factors (dyslipidemia, atherosclerosis, diabetes mellitus, obesity) for these diseases, but there are also other factors with important implications in the pathogenesis of vascular diseases (VD). …

ro (code pays fourni par la source)

Differential Metabolic Dysregulations in Hepatocellular Carcinoma and Cirrhosis: Insights into Lipidomic Signatures

Cristina-Paula Ursu, Luminița Furcea, Bogdan Procopeț, Răzvan Alexandru Ciocan et autres

Hepatocellular carcinoma (HCC), the most common primary liver malignancy, usually develops in patients with cirrhosis, yet the metabolic mechanisms that distinguish the two conditions remain poorly understood. This study aimed to explore metabolic dysregulations in HCC compared with cirrhosis and to identify …

ro (code pays fourni par la source)

Evaluating Scopus AI Versus Traditional Searches for Literature Review About Prepectoral Breast Reconstruction: An Exploratory Study

Ionuț Ștefan Ciule, Ariana‐Anamaria Cordoș, Răzvan Alexandru Ciocan, Andra Ciocan et autres

Background: Artificial intelligence tools are increasingly being used to assist literature reviews, but their effectiveness compared to traditional methods is not well established. This study compares Scopus AI with PubMed keyword searches on the topic of primary prepectoral breast reconstruction after radical …

ro (code pays fourni par la source)

Exploratory Insights into Gastric Cancer Metabolism Through Amino Acid and Acylcarnitine Profiling in Plasma Samples

Ștefan Ursu, Cristina-Paula Ursu, Luisa-Gabriela Bogos, Ioana-Ecaterina Pralea et autres

Background: Gastric cancer ranks fifth among the most prevalent malignancies, with poor prognosis due to limited early-stage diagnosis. Metabolic reprogramming plays a central role in GC development, sustaining carcinogenic processes. Methods: In this study, flow-injection tandem mass spectrometry was used to analyse …

ro (code pays fourni par la source)

An observational study on the parameters influencing the duration of forensic medicine expert reports in assessment of inmates’ health status in view of sentence interruption on medical grounds - conducted at the Cluj-Napoca Legal Medicine Institute between 2014 and 2018

Cristian Gherman, Armand Iustinian Enache, Cristian Delcea, Costel Vasile Siserman

Aim. The aim of this study is to identify and rank the causes determining the length of time required to draw up forensic expert reports for interrupting the execution of a prison sentence on medical grounds. Preparing this type of forensic expert …

The multi-factorial determinism of forensic expertise regarding sentence interruption on medical grounds and decision

Cristian Gherman, Alexandra Enache, Cristian Delcea

ro (code pays fourni par la source)

Unusual Circumstances of Death due to Domestic Animals

Cristian Gherman

The Open Access Journal of Surgery (OAJS) is a globally accepted journal that aims to publish innovative scientific developments and high quality information in all kinds of surgical research, education and clinical practice