Davide Amendola

Orally Bioavailable Dopamine D1/D5 Receptor-Biased Agonists to Study the Role of β-Arrestin in Treatment-Related Dyskinesia in Parkinson’s Disease

Rosa Marı́a Rodrı́guez Sarmiento, Nenad Manevski, Lothar Lindemann, Fabian Dey et autres

Dopamine replacement therapies for Parkinson’s disease often produce dyskinesias with long-term use. Published studies suggest that introducing β-arrestin signaling might be protective for dyskinesia. We advanced known noncatecholamine D1/D5 receptor G protein-biased agonists and found that removal of oxygen in the linker …

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Mechanism of bacterial predation via ixotrophy

Yun‐Wei Lien, Davide Amendola, Kang Soo Lee, Nina Bartlau et autres

Ixotrophy is a contact-dependent predatory strategy of filamentous bacteria in aquatic environments for which the molecular mechanism remains unknown. We show that predator-prey contact can be established by gliding motility or extracellular assemblages we call "grappling hooks." Cryo-electron microscopy identified the grappling …

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Mechanism of bacterial predation via ixotrophy

Yun‐Wei Lien, Davide Amendola, Kang Soo Lee, Nina Bartlau et autres

Abstract Predation allows bacteria to access alternative substrates in low-nutrient conditions. Ixotrophy has been proposed as a predatory lifestyle of multicellular filamentous bacteria in aquatic environments; however, the molecular mechanism remains unknown. Here we uncover by a multidisciplinary approach that ixotrophy requires …

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A Eulogy of the Ptolemaic Monarchy (P.Berol. inv. 13045, cols. A I–III)

Davide Amendola

II The Origin, Nature and Purpose of the Contents of the Papyrus

Davide Amendola

The Dialogue between Demades and Dinarchus at the Macedonian Court

Davide Amendola

I The Papyrus

Davide Amendola

A Eulogy of the Lagid Monarchy (P.Berol. inv. 13045, cols. A I–III)

Davide Amendola

The Dialogue between Demades and Dinarchus at the Macedonian Court (P.Berol. inv. 13045, cols. B I–G III)

Davide Amendola

III The Papyrus’ Contribution in Historical and Historiographical Terms

Davide Amendola

Greek, Roman and Byzantine Authors, Lexica and Collections of Fragments

Davide Amendola

The Demades Papyrus (P.Berol. inv. 13045)

Davide Amendola

Despite the significance of its contents, the so-called Demades papyrus (P.Berol. inv. 13045) has received scarce scholarly attention since the 1923 editio princeps by Karl Kunst. This unique late second-century BCE document of almost 430 lines was found in the Egyptian chora, …