Accès ouvert
2026
article
OpenAlex
Jialun Zhu, Xuanbing Cheng, M. Bahman Bahramian, Kuanming Yao et autres
Wearable microneedle biosensors promise real-time molecular monitoring for precision medicine but are limited by low sensitivity and tissue abrasion. Overcoming these challenges, we recast electrode functionality not merely as a sensing substrate but as a mechanism for resilient, high signal-to-noise ratio (SNR) …
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Accès ouvert
2023
article
OpenAlex
Shuyu Lin, Jialun Zhu, Justin Yeung, Tsung‐Yu Wu et autres
Ion-Selective Biosensors In article 2202141, Sam Emaminejad and co-workers develop a touch-based noninvasive system to monitor lithium-based pharmacotherapy. It utilizes a thin organohydrogel lithium ion-selective electrode (TOH-ISE) that has dehydration-resistant properties, minimizing signal drift, and allowing for sweat collection. The system is …
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2023
article
OpenAlex
Shuyu Lin, Jialun Zhu, Justin Yeung, Tsung‐Yu Wu et autres
Abstract Lithium is a drug widely employed for the treatment of bipolar disorder owing to its high efficacy in mood management and suicide prevention. However, this efficacy is often undermined by misdosing and nonadherence, and diligent drug monitoring is required during treatment. …
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Accès ouvert
2022
article
OpenAlex
Shuyu Lin, Xuanbing Cheng, Jialun Zhu, Bo Wang et autres
Therapeutic drug monitoring is essential for dosing pharmaceuticals with narrow therapeutic windows. Nevertheless, standard methods are imprecise and involve invasive/resource-intensive procedures with long turnaround times. Overcoming these limitations, we present a microneedle-based electrochemical aptamer biosensing patch (μNEAB-patch) that minimally invasively probes the …
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(code pays fourni par la source)