Janja Kopić

The MacBrain Resource Center ( MBRC ) rhesus macaque embryonic brain histology datasets

Valeria Mendoza-Silva, Emma Burke, Lucy Greene, Mikhail Rodov et autres

Abstract Datasets for the study of developing Non‐Human Primate (NHP) brain are scarce. Some of the reasons are related to the financial and technical obstacles that make the production of these datasets logistically challenging. NHP embryos of different and verified developmental ages …

us, hr, jp (code pays fourni par la source)

Orchestrated molecular changes of proliferative, migratory‐fibrillar, synaptic, and postmigratory compartments align with precocious cortex‐type specification in the early human pallium

Janja Kopić, Fran Bozic, Alisa Junaković Munjas, Željka Krsnik

Early development of the human pallium is shaped by transient cellular compartments that regulate the emergence of cytoarchitectonically distinct cortical types. At these stages, regional identity depends less on mature cortical layers-which form later in gestation-and more on the organization of transient …

hr (code pays fourni par la source)

Structural variations in evolutionary novel genomic regions: new insights into neurodevelopmental disorders by long-read DNA Sequencing

Martina Rincic, Janja Kopić, Valentina Klein, Zeljka Krsnik et autres

BACKGROUND: Neurodevelopmental disorders (NDDs) are highly diverse conditions often associated with genetic abnormalities. However, a large number of NDD cases remain undiagnosed despite thorough genetic testing using short-read sequencing and chromosomal microarray analysis. Emerging evidence indicates that structural variants (SVs) in evolutionarily …

hr, de (code pays fourni par la source)

Additional file 2 of Structural variations in evolutionary novel genomic regions: new insights into neurodevelopmental disorders by long-read DNA Sequencing

Martina Rinčić, Janja Kopić, Valentina Klein, Zeljka Krsnik et autres

Supplementary Material 2.

hr, de (code pays fourni par la source)

Additional file 1 of Structural variations in evolutionary novel genomic regions: new insights into neurodevelopmental disorders by long-read DNA Sequencing

Martina Rinčić, Janja Kopić, Valentina Klein, Zeljka Krsnik et autres

Supplementary Material 1.

hr, de (code pays fourni par la source)

Additional file 2 of Structural variations in evolutionary novel genomic regions: new insights into neurodevelopmental disorders by long-read DNA Sequencing

Martina Rinčić, Janja Kopić, Valentina Klein, Zeljka Krsnik et autres

Supplementary Material 2.

hr, de (code pays fourni par la source)

Structural variations in evolutionary novel genomic regions: new insights into neurodevelopmental disorders by long-read DNA Sequencing

Martina Rinčić, Janja Kopić, Valentina Klein, Zeljka Krsnik et autres

Abstract Background Neurodevelopmental disorders (NDDs) are highly diverse conditions often associated with genetic abnormalities. However, a large number of NDD cases remain undiagnosed despite thorough genetic testing using short-read sequencing and chromosomal microarray analysis. Emerging evidence indicates that structural variants (SVs) in …

hr, de (code pays fourni par la source)

Structural variations in evolutionary novel genomic regions: new insights into neurodevelopmental disorders by long-read DNA Sequencing

Martina Rinčić, Janja Kopić, Valentina Klein, Zeljka Krsnik et autres

Abstract Background Neurodevelopmental disorders (NDDs) are highly diverse conditions often associated with genetic abnormalities. However, a large number of NDD cases remain undiagnosed despite thorough genetic testing using short-read sequencing and chromosomal microarray analysis. Emerging evidence indicates that structural variants (SVs) in …

hr, de (code pays fourni par la source)

Additional file 1 of Structural variations in evolutionary novel genomic regions: new insights into neurodevelopmental disorders by long-read DNA Sequencing

Martina Rinčić, Janja Kopić, Valentina Klein, Zeljka Krsnik et autres

Supplementary Material 1.

hr, de (code pays fourni par la source)

Mapping the developmental profile of ventricular zone–derived neurons in the human cerebellum

Anders W. Erickson, Liam D. Hendrikse, Jake Millman, Zachary Thomson et autres

The cerebellar ventricular zone (VZ) is the primary source of progenitors that generate cerebellar GABAergic neurons, including Purkinje cells (PCs) and interneurons (INs). This study provides detailed characterization of human cerebellar GABAergic neurogenesis using transcriptomic and histopathological analyses and reveals conserved and …

ca, gb, fr, hr, lb, us (code pays fourni par la source)

Initial regional cytoarchitectonic differences in dorsal and orbitobasal human developing frontal cortex revealed by spatial transcriptomics

Janja Kopić, Parthiv Haldipur, Kathleen J. Millen, Ivica Kostović et autres

hr, us (code pays fourni par la source)

Increased NLRP1 mRNA and Protein Expression Suggests Inflammasome Activation in the Dorsolateral Prefrontal and Medial Orbitofrontal Cortex in Schizophrenia

Ena Španić Popovački, Dora Vogrinc, Heidi R. Fuller, Lea Langer Horvat et autres

Schizophrenia is a complex mental condition, with key symptoms marked for diagnosis including delusions, hallucinations, disorganized thinking, reduced emotional expression, and social dysfunction. In the context of major developmental hypotheses of schizophrenia, notably those concerning maternal immune activation and neuroinflammation, we studied …

hr, gb, us, de (code pays fourni par la source)