David Aguilera‐Alonso

Mpox in Children and Adolescents

David Aguilera‐Alonso, Nadia Adjoa Sam-Agudu, Hypolite Muhindo-Mavoko, Zoi Dorothea Pana

Mpox is a zoonotic disease caused by the monkeypox virus (MPXV), a DNA virus of the Orthopoxvirus genus. First detected in humans in 1970 in the Democratic Republic of the Congo (DRC), mpox has historically been endemic to Central and West Africa, …

es, Ghana, Nigéria, us, République démocratique du Congo, cy (code pays fourni par la source)

Short- and Long-term Humoral Response of Immunosuppressed Children to SARS-CoV-2 BNT162b2 Vaccine

Alfredo Tagarro, Irati Gastesi, An Hotterbeekx, David Aguilera‐Alonso et autres

INTRODUCTION: This study aimed to evaluate in detail the short- and long-term humoral responses to the BNT162b2 (BioNTech, SE, Mainz, Germany/Pfizer Inc, New York, NY) vaccine in immunosuppressed children 5-11 years old compared with healthy children. METHODS: A prospective cohort study was …

es, be, it, cn (code pays fourni par la source)

Paediatric invasive group A streptococcal infections and associations with viral infections in 15 European countries after lifting non-pharmaceutical interventions against SARS-CoV-2: an interrupted time-series analysis

Léa Lenglart, David Aguilera‐Alonso, Daniel Blázquez‐Gamero, Navin P. Boeddha et autres

Background: After lifting non-pharmaceutical interventions (NPIs) against the transmission of SARS-CoV-2, various countries experienced an increase in invasive Group A Streptococcal (iGAS) infections. We aimed to characterise the paediatric outbreak across Europe and to analyse the influence of viral infections. Methods: We …

fr, us, nl, es, it, lv, gr, gb, pt, dk, ch, at, pl, si, be, is, de (code pays fourni par la source)

Sharp increase in the incidence and severity of invasive Streptococcus pyogenes infections in children after the COVID-19 pandemic (2019-2023): A nationwide multicenter study

Elvira Cobo-Vázquez, David Aguilera‐Alonso, David Grandioso-Vas, Anna Maria Gamell et autres

Objectives A global surge in pediatric invasive group A streptococcal infection (iGAS) was reported after autumn 2022. This study analyzed the epidemiology and severity of iGAS in Spain, comparing two periods; P1: pre-outbreak (January 2019-September 2022) versus P2: outbreak (October 2022-July 2023). …

es (code pays fourni par la source)

Plasma calprotectin as a severity biomarker in pediatric invasive Streptococcus pyogenes infections: insights from a multicenter immune profiling study during an outbreak

José Avendaño Ortiz, David Aguilera‐Alonso, Concepción M. Rodríguez, Jesús Oteo et autres

PURPOSE: To characterize the immune signature of pediatric invasive Streptococcus pyogenes infections (iGAS) and identify host biomarkers associated with disease severity. METHODS: Plasma samples (n = 32) were collected during an iGAS outbreak from a multicentric Spanish pediatric cohort, including patients with …

es (code pays fourni par la source)

Case Series: Off-label Use of Dalbavancin in Pediatric Gram-positive Infections

María Guillén-Martínez, David Aguilera‐Alonso, Juan Luis Santos-Pérez, Álvaro Vázquez-Pérez et autres

BACKGROUND: There is a growing interest in the use of dalbavancin as treatment for infections caused by Gram-positive microorganisms. Due to its long half-life, linear pharmacokinetics and good tolerability, it has been used in different clinical scenarios, including off-label indications. Studies are …

es (code pays fourni par la source)

Changes in the epidemiology of acute mastoiditis according to the implementation of pneumococcal vaccination in a Spanish population

Ángela Manzanares, David Aguilera‐Alonso, María Teresa Burguillo Escobar, Sara Vigil‐Vázquez et autres

es (code pays fourni par la source)

Corrigendum: SARS-CoV2 infection during pregnancy causes persistent immune abnormalities in women without affecting the newborns

Elena Vázquez‐Alejo, Laura Tarancón‐Díez, Itzíar Carrasco, Sara Vigil‐Vázquez et autres

There was a mistake in the Funding statement, an incorrect number was used. The correct number is "2015C03Bd051.". The publisher apologizes for this mistake.The original version of this article has been updated. PAGE \* Arabic \* MERGEFORMAT 3In the published article, there …

es (code pays fourni par la source)

Changes in the epidemiology of acute mastoiditis according to the implementation of pneumococcal vaccination in a Spanish population

Ángela Manzanares, David Aguilera‐Alonso, María Teresa Burguillo Escobar, Sara Vigil‐Vázquez et autres

es (code pays fourni par la source)

Persistent Symptoms (Lasting Longer than 1 Year) in Children Hospitalized with Acute COVID-19 Versus Other Conditions

Marta Hernández Conde, Irati Gastesi, Lucía de Pablo, Sara Villanueva-Medina et autres

Background: We evaluated the prevalence and characteristics of persistent signs and/or symptoms in children and young people (CYP) one year after hospitalization for acute COVID-19 compared with a control group of CYP hospitalized for other conditions. Methods: We conducted an observational study …

es, it (code pays fourni par la source)

Impact of the COVID-19 Pandemic on Pediatric Bacterial Community–acquired Pneumonia: A Multicenter Retrospective Study in Madrid, Spain

David Aguilera‐Alonso, Juan Sánchez-Cañete, Leyre Ventura McArdle, Teresa del Rosal et autres

This study conducted in Madrid, Spain between 2018 and 2023 shows a significant decrease in the pediatric bacterial community-acquired pneumonia cases during the COVID-19 pandemic, followed by a notable postpandemic increase surpassing prepandemic incidence. Streptococcus pneumoniae remains predominant, with an increasing prevalence …

es (code pays fourni par la source)

Diagnostic potential of combining plasma biomarkers of tissue damage and inflammation in pediatric TB

Andrea López-Suárez, María del Mar Santos Sebastián, Alicia Hernanz‐Lobo, Elena María Rincón‐López et autres

INTRODUCTION: Immune-based diagnostic tests for tuberculosis (TB) have suboptimal sensitivity in children and cannot differentiate between latent infection (LTBI) and active disease. This study evaluated the diagnostic potential of a broad range of biomarkers of tissue damage and inflammation in unstimulated plasma …

es, us, au, gb (code pays fourni par la source)