Imaging pulmonary P-glycoprotein activity with aerosolized [99mTc]Tc-sestamibi in mice
Severin Mairinger, Jakob Pfeiffer-Vogl, Lena Zachhuber, Johann Stanek et autres
0 citationsEuropean Journal of Pharmaceutical Sciences
Severin Mairinger
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93Publications signalées
1280Citations signalées
1Affiliations récentes
Institutions déclarées
Domaines associés
Drug Transport and Resistance MechanismsPharmacological Effects and Toxicity StudiesRadiopharmaceutical Chemistry and ApplicationsMedical Imaging Techniques and ApplicationsAmino Acid Enzymes and Metabolism
Publications récentes
In vivo evidence of functional OATP2B1 activity in human skeletal muscle using [11C]erlotinib PET
Matthias Jackwerth, Severin Mairinger, Marcus Hacker, N. Tournier et autres
0 citationsEuropean Journal of Pharmaceutical Sciences
Evaluating methodological constraints in PET imaging of neuropeptide Y2 receptors with N-[11C]-methyl-(R)-JNJ-31020028 in brains of C57BL/6J mice
Karsten Bamminger, Eduardo Felipe Alves Fernandes, Lena Zachhuber, Ines Lopez-Martinez et autres
0 citationsEJNMMI Radiopharmacy and Chemistry
Imaging P-glycoprotein function at the blood-brain barrier in drug-resistant epilepsy using [11C]metoclopramide
Louise Breuil, Inés Ariño, Myriam El Biali, S. Rodrigo et autres
1 citationEuropean Journal of Nuclear Medicine and Molecular Imaging
Evaluation of dose linearity in the systemic availability and pharmacokinetics of topically administered diclofenac: A 14C-microdosing study in healthy volunteers
Severin Mairinger, Mihye Kwon, Martin Bauer, Jin-Ho Song et autres
0 citationsDrug Metabolism and Disposition
Functional MRP1 activity in human skeletal muscle
Matthias Jackwerth, Severin Mairinger, Markus Zeitlinger, Oliver Langer
0 citationsBritish Journal of Pharmacology
Effect of probenecid on the whole-body disposition of 6-bromo-7-[11C]methylpurine in humans assessed with long axial field-of-view PET/CT
Matthias Jackwerth, Severin Mairinger, Ivo Rausch, Maria Weber et autres
2 citationsEuropean Journal of Nuclear Medicine and Molecular Imaging
[11C]Metoclopramide PET can detect a seizure-induced up-regulation of cerebral P-glycoprotein in epilepsy patients
Myriam El Biali, Louise Breuil, Matthias Jackwerth, Severin Mairinger et autres
7 citationsFluids and Barriers of the CNS
First-in-human evaluation of 6-bromo-7-[11C]methylpurine, a PET tracer for assessing the function of multidrug resistance-associated proteins in different tissues
Severin Mairinger, Matthias Jackwerth, Zacharias Chalampalakis, Ivo Rausch et autres
2 citationsEuropean Journal of Nuclear Medicine and Molecular Imaging
St. John's wort extract with a high hyperforin content does not induce P‐glycoprotein activity at the human blood–brain barrier
Myriam El Biali, Michael Wölfl‐Duchek, Matthias Jackwerth, Severin Mairinger et autres
7 citationsClinical and Translational Science
Advancing 6-bromo-7-[11C]methylpurine to clinical use: improved regioselective radiosynthesis, non-clinical toxicity data and human dosimetry estimates
Severin Mairinger, Matthias Jackwerth, Ondřej Soukup, Matthias Blaickner et autres
2 citationsEJNMMI Radiopharmacy and Chemistry
Functionalization of 68Ga-Radiolabeled Nanodiamonds with Octreotide Does Not Improve Tumor-Targeting Capabilities
Thomas Wanek, Marco Raabe, Md Noor A Alam, Thomas Filip et autres
2 citationsPharmaceuticals
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