Nipun Babu Varukattu

Chemical aspects of controlled cisplatin release and apoptosis via Nerium oleander latex nano-carriers in breast cancer cells

Sultan Saad Almadhhi, Raju Suresh Kumar, DV Surya Prakash, Nipun Babu Varukattu et autres

Plant-derived nano-carriers offer a sustainable and targeted strategy for cancer therapy. This study reports the synthesis and characterization of a latex-hybrid nano-carrier derived from Nerium oleander (LHNC), engineered for cisplatin (CDDP) delivery in breast cancer models. Physicochemical analyses confirmed stable, porous nanostructures …

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Mass spectrometry imaging tutorial: From cancer biomarker discovery to clinical applications

Amirsalar Mansouri, Nipun Babu Varukattu, Brennan J. Curole, Omeed Moaven et autres

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Label-free electrochemical assessment of human serum and cancer cells to determine the folate receptor cancer biomarker

Chandrababu Rejeeth, Rafa Almeer, Alok Sharma, Nipun Babu Varukattu

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A Novel Azathioprine Polysaccharide Nanoparticle Enhances the Efficacy of Systemic Lupus Erythematosus Therapy

Chandrababu Rejeeth, Nipun Babu Varukattu, Alok Sharma, Raju Suresh Kumar et autres

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A novel device for swift and efficient CD44 protein digestion of pipette tips in human serum

Chandrababu Rejeeth, Nipun Babu Varukattu, Raju Suresh Kumar, Abdulrahman I. Almansour et autres

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Bimetallic Metal–Organic Framework Nanoparticles for Monitoring Metabolic Changes in Cardiovascular Disorders

Chandrababu Rejeeth, Alok Sharma, Raju Suresh Kumar, Abdulrahman I. Almansour et autres

A group of disorders known as cardiovascular diseases (CVDs) affect the blood vessels that supply the heart muscle. CVDs are the leading global cause of death; however, the absence of a successful metabolomic strategy has impeded the advancement of CVD research. Because …

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A Novel Device for Swift and Efficient CD44 Protein Digestion of Pipette Tips in Human Serum

Chandrababu Rejeeth, Nipun Babu Varukattu, Raju Suresh Kumar, Abdulrahman I. Almansour et autres

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In vivo delivery of nuclear targeted drugs for lung cancer using novel synthesis and functionalization of iron oxide nanocrystals

Sreevani Vellingiri, Chandrababu Rejeeth, Nipun Babu Varukattu, Alok Sharma et autres

Iron nanoparticles are typically made from inorganic precursors, but for the first time, we synthesized-Fe 2 O 3 -NCs from goat blood (a bio-precursor) employing the RBC lysis method (a molecular level approach).

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Targeted and Intrinsic Activity of HA-Functionalized PEI-Nanoceria as a Nano Reactor in Potential Triple-Negative Breast Cancer Treatment

Nipun Babu Varukattu, Wan‐Wan Lin, Raju Vivek, Chandrababu Rejeeth et autres

Although there has been considerable achievement in the field of breast cancer therapeutics, tackling the disturbing issue of highly potent triple-negative breast cancer (TNBC) still remains a hurdle in cancer therapeutics. Here, for the first time we propose a poly(ethylenimine) (PEI)-mediated approach …

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Biosynthesis and characterization of copper oxide nanoparticles from indigenous fungi and its effect of photothermolysis on human lung carcinoma

Kandasamy Saravanakumar, Sabarathinam Shanmugam, Nipun Babu Varukattu, Davoodbasha MubarakAli et autres

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Green synthesis and characterization of biologically active nanosilver from seed extract of Gardenia jasminoides Ellis

Kandasamy Saravanakumar, Ramachandran Chelliah, Sabarathinam Shanmugam, Nipun Babu Varukattu et autres

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Nanostructured pH-responsive biocompatible chitosan coated copper oxide nanoparticles: A polymeric smart intracellular delivery system for doxorubicin in breast cancer cells

Nipun Babu Varukattu, Raju Vivek, Chandrababu Rejeeth, Ramar Thangam et autres

In this study, we report a novel feasible single step reduction method for the active synthesis of biocompatible chitosan coated copper oxide nanoparticles (Cs-CuO NPs), for loading and delivery of doxorubicin (DOX) into breast cancer cells. The formulated nanoparticles (NPs) were characterized …

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