Daiichiro Hasegawa

Complement-related genetic analysis for Japanese children with transplant-associated thrombotic microangiopathy

A Yamada, Shun Nagasawa, Midori Nakagawa, Sachiyo Kamimura et autres

Background Transplant-associated thrombotic microangiopathy (TA-TMA) is a life-threatening complication of hematopoietic stem cell transplantation (HSCT). Previous reports in the United States have suggested that TA-TMA is caused by complement-related genetic variants. However, these findings need to be validated in other countries and …

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Clinical and microbiological characteristics of viridans group streptococcal bacteremia in pediatric and adolescent patients with cancer

Natsuko Yoshikawa, Suguru Uemura, Shinsuke Mizuno, Saki Tanaka et autres

Viridans group streptococci (VGS) are an important cause of bacteremia inpediatric oncology patients and hematopoietic stem cell transplantation (HSCT) recipients, with the potential to viridans streptococcal shock syndrome (VSSS). Increasing β-lactam resistance has raised concerns about the adequacy of current empiric treatment …

Clinical and microbiological characteristics of viridans group streptococcal bacteremia in pediatric and adolescent patients with cancer

Natsuko Yoshikawa, Suguru Uemura, Shinsuke Mizuno, Saki Tanaka et autres

Viridans group streptococci (VGS) are an important cause of bacteremia inpediatric oncology patients and hematopoietic stem cell transplantation (HSCT) recipients, with the potential to viridans streptococcal shock syndrome (VSSS). Increasing β-lactam resistance has raised concerns about the adequacy of current empiric treatment …

jp (code pays fourni par la source)

Clinical and microbiological characteristics of viridans group streptococcal bacteremia in pediatric and adolescent patients with cancer

Natsuko Yoshikawa, Suguru Uemura, Shinsuke Mizuno, Saki Tanaka et autres

Viridans group streptococci (VGS) are an important cause of bacteremia inpediatric oncology patients and hematopoietic stem cell transplantation (HSCT) recipients, with the potential to viridans streptococcal shock syndrome (VSSS). Increasing β-lactam resistance has raised concerns about the adequacy of current empiric treatment …

Effects of delayed sodium thiosulfate on cisplatin-induced ototoxicity in pediatric and adolescent patients with cancer: Results from the Japanese Children’s Cancer Group STS-J01 study.

Eiso Hiyama, Isamu Saeki, Eriko Uchida, Makiko Mori et autres

10052 Background: Cisplatin is a cornerstone of therapy for pediatric, adolescent, and adult solid tumors but frequently causes irreversible, dose-dependent ototoxicity. Delayed administration of sodium thiosulfate (PEDMARK) has demonstrated otoprotection in Western trials. STS-J01 evaluated the efficacy, safety, and pharmacokinetics of delayed …

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Impact of Conditioning Regimen Type on Outcomes in Pediatric Patients with De Novo Advanced Myelodysplastic Syndrome Undergoing Hematopoietic Stem Cell Transplantation

Suguru Uemura, Daiichiro Hasegawa, Nao Yoshida, Dai Keino et autres

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Effect of Inflammatory Bowel Disease on Clinical Outcomes of Hematopoietic Cell Transplantation for Inborn Errors of Immunity

Ryu Yanagisawa, Yoji Sasahara, Michiko Kajiwara, Masataka Ishimura et autres

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Outcome of chemotherapy dose reduction in overweight Japanese children with acute lymphoblastic leukemia

S. Katayama, Kunihiko Moriya, Toshihiko Imamura, Kosuke Tamefusa et autres

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H3K27me3 and HOXA9 expression predict prognosis in pediatric acute myeloid leukemia: an epigenetic-transcriptional correlation study

Hironori Goto, Souichi Suenobu, Yuhki Koga, Shunsuke Yamamoto et autres

Background Epigenetic dysregulation plays a central role in pediatric acute myeloid leukemia (AML), yet its clinical relevance remains underexplored. This study primarily aimed to elucidate the clinical effect of H3K27me3 and H3K4me3 status on pediatric acute myeloid leukemia. We evaluated the prognostic …

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Evaluation of Minimal Residual Disease in Patients with Neuroblastoma

Nobuyuki Yamamoto, Akihiro Nishimura, Tomoko Fujikawa, Shotaro Inoue et autres

Neuroblastoma (NB) is a pediatric extracranial solid tumor that accounts for approximately 15% of all pediatric cancer deaths. More than 50% of patients with newly diagnosed NB are classified into a high-risk group with an approximately 50% long-term survival rate. Although most …

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2636 Proton beam therapy for intracranial germ cell tumors in pediatric, adolescent, and young adult patients: Kobe Proton Center experience

Yumi Kokubo, Yusuke Demizu, Iwashita Kazuma, SungChul Park et autres

Incidence of and factors associated with hypophosphatemia in children and adolescents receiving cancer treatment: a single-center, retrospective study

Kenji Kishimoto, Shogo Horikawa, Suguru Uemura, Sayaka Hyodo et autres

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