Michael T. Zimmerman

Fine Mapping of MHC Region Identifies Novel Susceptibility Loci in Multiple Myeloma When Comparing With Its Precursor Monoclonal Gammopathy of Unknown Significance

Shahram Arsang-Jang, Ben Massat, Gokul Pareek, Jing Han et autres

ABSTRACT Genome‐wide association studies have linked major histocompatibility complex (MHC) region loci to immune‐related diseases, but their role in multiple myeloma (MM) progression from monoclonal gammopathy of undetermined significance (MGUS) remains unclear. This case–control study included 238 individuals with MGUS (> 5 …

us, cn (code pays fourni par la source)

Observations of the Upper Ocean from Autonomous Platforms during the Passage of Extratropical Cyclone Epsilon (2020)

Michael T. Zimmerman

Hurricane Epsilon (2020) was a late-season, category-3 tropical cyclone that underwent extratropical transition and became Extratropical Cyclone Epsilon on 26 October. The upper ocean response to the passage of the storm was observed by three types of autonomous platforms: the eXpendable Spar …

Digital Imaging Analysis for Quantitative Subcellular Localization of MRP2 during Hepatic Ischemia–Reperfusion Injury in a Rat Model: Can You Capture Time?

Jae‐eun Kim, Suresh N. Kumar, Seung‐Keun Hong, Yushi Yang et autres

us (code pays fourni par la source)

Abstract 2243: Comprehensive genomic profiling - does timing matter

Bicky Thapa, Gulrayz Ahmed, Matthew Lasowski, James P. Thomas et autres

Abstract Background: Comprehensive Genomic Profiling (CGP) is performed routinely in patients (pts) with metastatic solid tumors (MSTs) to guide treatment. However, there is variability in the interval between metastatic diagnosis (MDx) and performance of CGP based on histology and/or provider preference. We …

us (code pays fourni par la source)

Secondary Hematologic Malignancies after Autologous Stem Cell Transplantation for Multiple Myeloma Are Associated with a Distinct Mutational Profile

Ariel Kleman, Arun K. Singavi, Lauren Pommert, Michael T. Zimmerman et autres

Background: Patients (pts) diagnosed with multiple myeloma (MM) are at risk for developing secondary hematologic malignancies (SHM). The etiology of SHM-associated genetic alterations (GAs) is unclear. We hypothesized that the GAs present in MM-associated SHMs would have a distinct profile compared to …

us (code pays fourni par la source)

Variants in DOCK3 cause developmental delay and hypotonia

Kimberly Wiltrout, Alejandro Ferrer, Ingrid M.B.H. van de Laar, Kazuhiko Namekata et autres

us, nl, jp (code pays fourni par la source)

The clinical relevance of BAALC and ERG expression levels in pediatric AML

Malou Hermkens, Marry M. van den Heuvel‐Eibrink, Susan T.C.J.M. Arentsen-Peters, André Baruchel et autres

nl, fr, cz (code pays fourni par la source)

Linkage Between Dynamics and Assembly of Ribosomal Proteins

Brittany Nicole Burton, Michael T. Zimmerman, Robert L. Jernigan, Yongmei Wang

us (code pays fourni par la source)

Clinical implications of FLT3 mutations in pediatric AML

Soheil Meshinchi, Todd A. Alonzo, Derek L. Stirewalt, Michel C. Zwaan et autres

Activating mutations of the FLT3 gene occur because of an internal tandem duplication of the juxta-membrane domain (FLT3/ITD) or point mutation of the activation loop domain (FLT3/ALM). The presence of FLT3 mutations as well as the allelic ratio of FLT3/ITD (ITD-AR, mutant-wild …

us (code pays fourni par la source)