Accès ouvert
2025
article
OpenAlex
Windsor Wen‐Jin Chao, Howard Wen‐Haur Chao, Pai‐Huei Peng, Yi‐Tzu Lee et autres
Retinal ischemia is a key factor in the progression of vision-threatening ocular diseases, including central retinal artery/vein occlusion, exudative age-related macular degeneration (eAMD), and proliferative diabetic retinopathy. This study investigates the effects of paeoniflorin along with its related neuroprotective molecular pathways in …
ca, gb, tw
(code pays fourni par la source)
2025
article
OpenAlex
Winsdor Wen‐Jin Chao, Howard Wen‐Haur Chao, Hsiao‐Ming Chao
Aims/Purpose: Retinal ischemia‐associated ocular disorders are vision threatening. The aim of the present study is to assess the potential of paeoniflorin in alleviating retinal ischemic injury and to uncover the mechanisms involved. Methods: Cultured retinal cells were subjected to oxygen glucose deprivation …
gb, ca, tw
(code pays fourni par la source)
2025
article
OpenAlex
Howard Wen‐Haur Chao, Hsiao‐Ming Chao
Aims/Purpose: To evaluate the efficacy of combined therapy (verteporfin PDT plus anti‐VEGF) vs. anti‐VEGF monotherapy in symptomatic macular polypoidal choroidal vasculopathy (PCV) and its underlying therapeutic mechanisms. Methods: In this retrospective indocyanine green angiography (ICG)–proved PCV study, 21 Chinese (mean age: 67.50 …
gb, tw
(code pays fourni par la source)
2025
article
OpenAlex
Howard Wen‐Haur Chao, Windsor Wen‐Jin Chao, Hsiao‐Ming Chao
Aims/Purpose: This study aimed at comparing the clinical outcomes of femtosecond laser‐assisted cataract surgery (FSACS) performing astigmatic keratotomy (AK) and toric intraocular lens (IOLt) implantation for astigmatism correction. Methods: Based on autorefractor and corneal topography, all patients underwent pre‐operative and postoperative examinations …
gb, tw, ca
(code pays fourni par la source)
2025
article
OpenAlex
Winsdor Wen‐Jin Chao, Howard Wen‐Haur Chao, Hsiao‐Ming Chao
Aims/Purpose: Retinal ischemia‐associated ocular disorders are vision threatening. The aim of the present study is to assess the potential of paeoniflorin in alleviating retinal ischemic injury and to uncover the mechanisms involved. Methods: Cultured retinal cells were subjected to oxygen glucose deprivation …
gb, ca, tw
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Windsor Wen‐Jin Chao, Howard Wen‐Haur Chao, Hung‐Fu Lee, Hsiao‐Ming Chao
Retinal ischemia plays a vital role in vision-threatening retinal ischemic disorders, such as diabetic retinopathy, age-related macular degeneration, glaucoma, etc. The aim of this study was to investigate the effects of S-allyl L-cysteine (SAC) and its associated therapeutic mechanism. Oxidative stress was …
ca, gb, tw
(code pays fourni par la source)
2024
article
OpenAlex
Howard Wen‐Haur Chao, Hsiao‐Ming Chao
Aims/Purpose: Retinal ischaemic disorders, including retinal vascular occlusion, age‐related macular degeneration and glaucoma, pose a threat to vision. This study examines the potential protective effects of catalpol against retinal ischaemia. Methods: RGC‐5 cells were cultured in DMEM with 10% FBS, penicillin (100 …
gb, tw
(code pays fourni par la source)
2024
article
OpenAlex
Windsor Wen‐Jin Chao, Hsiao‐Ming Chao
Aims/Purpose: Retinal ischaemia plays an important role in vision threatening retinal ischaemic disorders, such as central/branch RAO, nvAMD and normal tension glaucoma. The aim of this study was to determine the effects of S‐allyl L‐cysteine (SAC) and its underlying mechanism. Methods: Porcine …
ca, gb, tw
(code pays fourni par la source)
Accès ouvert
2020
article
OpenAlex
Ding-Ying Liao, Jorn‐Hon Liu, Yuping Zheng, Jianming Wang et autres
Purpose. To investigate the efficacy of idiopathic macular pucker (epimacular membrane) surgery and to identify the possible prognostic factor. Methods. This was a retrospective study which enrolled 38 patients with idiopathic macular pucker who underwent 23-gauge pars plana vitrectomy (PPV) with indocyanine …
cn, tw
(code pays fourni par la source)
Accès ouvert
2020
article
OpenAlex
Howard Wen‐Haur Chao, Yu-Kuang Chen, Jorn‐Hon Liu, Hsin-May Lin et autres
Abstract Background Emodin has been proved to have an anti-ischemic effect on the brain, however little research has been done on its effect on vision-threatening retinal ischemia. Thus, an investigation was carried out into the hypothetical efficacy of emodin against retinal ischemia …
tw
(code pays fourni par la source)
Accès ouvert
2020
article
OpenAlex
Ding-Ying Liao, Jorn‐Hon Liu, Yuping Zheng, Huei-Wen Shiu et autres
BACKGROUND: SD-OCT is becoming commonplace in everyday practice. Vitreomacular adhesions (VMAs) are being more routinely diagnosed. Predictive studies to the natural course of VMA are thus clinically significant. Spectral domain-optical coherence tomography (SD-OCT) was presently utilized to analyze the incidence of floaters, …
cn, tw, kr, us
(code pays fourni par la source)
Accès ouvert
2020
article
OpenAlex
Windsor Wen‐Jin Chao, Yu-Kuang Chen, Howard Wen‐Haur Chao, Wynn Hwai-Tzong Pan et autres
Purpose. Retinal ischemia is a medical condition associated with numerous retinal vascular disorders, such as age‐related macular degeneration, glaucoma, and diabetic retinopathy. This in vitro cell and in vivo animal study investigated not only the protective effect of S‐allyl L‐cysteine (SAC, an …
tw
(code pays fourni par la source)