A Kirn

Erratum: Corrigendum: The zebrafish reference genome sequence and its relationship to the human genome

Kerstin Howe, Matthew D. Clark, Carlos Torroja, James Torrance et autres

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The zebrafish reference genome sequence and its relationship to the human genome

Kerstin Howe, Matthew D. Clark, Carlos Torroja, James Torrance et autres

A high-quality sequence assembly of the zebrafish genome reveals the largest gene set of any vertebrate and provides information on key genomic features, and comparison to the human reference genome shows that approximately 70% of human protein-coding genes have at least one …

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Improved HIV-1 RNA quantitation by COBAS® AmpliPrep/COBAS® TaqMan® HIV-1 Test, v2.0 using a novel dual-target approach

Dorothea Sizmann, Joachim Glaubitz, Christian O. Simon, Sebastian Goedel et autres

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Selected Abstracts

R. Vazeux, R. Esser, Hagen von Briesen, W. Brugger et autres

Nekrologe

W.A. Vischer, X. Bühlmánn, H. Bruhin, J.S. Pitton et autres

Mitglieder-Liste der Schweizerischen Mikrobiologischen Gesellschaft

W.A. Vischer, X. Bühlmánn, H. Bruhin, J.S. Pitton et autres

JAK2V617F mutation status identifies subtypes of refractory anemia with ringed sideroblasts associated with marked thrombocytosis

Annette Schmitt‐Graeff, Swee‐Sen Teo, Manfred Olschewski, Franz X. Schaub et autres

BACKGROUND: Refractory anemia with ringed sideroblasts and marked thrombocytosis (RARS-T) was recently shown to be a JAK2-V617F mutation-related disorder. To determine the frequency and the prognostic significance of this mutation, we retrospectively evaluated 23 patients with platelet counts more than 600 x …

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Large-scale mapping of mutations affecting zebrafish development

Robert Geisler, Gerd-Jörg Rauch, Silke Geiger‐Rudolph, Andrea N. Albrecht et autres

BACKGROUND: Large-scale mutagenesis screens in the zebrafish employing the mutagen ENU have isolated several hundred mutant loci that represent putative developmental control genes. In order to realize the potential of such screens, systematic genetic mapping of the mutations is necessary. Here we …

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Protein Microarrays - A Promising Tool for Cancer Diagnosis.

Nicole Schneiderhan‐Marra, A Kirn, Anette Döttinger, Markus F. Templin et autres

Within recent years, protein microarrays have been developed to quantify a large number of parameters present in a given sample simultaneously. Such miniaturised and parallelised sandwich immunoassays are of general interest for all proteomic and diagnostic approaches in which several parameters have …

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A zebrafishsox9gene required for cartilage morphogenesis

Yi‐Lin Yan, Craig T. Miller, Robert M. Nissen, Amy Singer et autres

The molecular genetic mechanisms of cartilage construction are incompletely understood. Zebrafish embryos homozygous for jellyfish (jef) mutations show craniofacial defects and lack cartilage elements of the neurocranium, pharyngeal arches, and pectoral girdle similar to humans with campomelic dysplasia. We show that two …

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A radiation hybrid map of the zebrafish genome

Robert Geisler, Gerd-Jörg Rauch, Herwig Baier, Frauke van Bebber et autres

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[Viruses and macrophages].

F. Morinet, A Kirn