Profil bibliographique

Olivier Nicolas

Informations fournies par OpenAlex. Research Africa ne déduit ni nationalité, ni poste, ni coordonnées personnelles.

49Publications signalées

1893Citations signalées

2Affiliations récentes

Institutions déclarées

Sanofi (France)Vertex Pharmaceuticals (United States)

Domaines associés

Hepatitis C virus researchHIV/AIDS drug development and treatmentPlant Virus Research StudiesPharmacogenetics and Drug MetabolismHepatitis B Virus Studies

Publications récentes

Accès ouvert 2025 articleOpenAlex

Unexpected Clinical Drug-Drug Interaction of Fexinidazole on Midazolam Pharmacokinetics: Insights into Underlying Mechanisms from Clinical Phase I Study Results and Supporting In Vivo/Vitro Evidence

Matthieu Gassiot, Priscilla Brun, Valérie Wauthier, Franck Da Silva et autres

1 citationClinical Drug Investigation

Accès ouvert 2025 articleOpenAlex

Small molecule APOL1 inhibitors as a precision medicine approach for APOL1-mediated kidney disease

Barry J. Zimmerman, Leslie Dakin, A H Fortier, Evanthia Nanou et autres

19 citationsNature Communications

Accès ouvert 2024 preprintOpenAlex

Small Molecule APOL1 Inhibitors as a Precision Medicine Approach for APOL1-mediated Kidney Disease

Brandon Zimmerman, Leslie Dakin, A H Fortier, Evanthia Nanou et autres

2 citationsResearch Square

Accès ouvert 2024 articleOpenAlex

A phase I trial assessing the safety, pharmacokinetics, cerebrospinal fluid penetrance, and food effect of BTK inhibitor tolebrutinib in healthy volunteers

Marie‐José Cabanis, Olivier Nicolas, Olivier Vitse, Christelle Jan et autres

9 citationsClinical and Translational Science

Accès ouvert 2023 articleOpenAlex

Absorption, Metabolism, and Excretion of [14C]-Tolebrutinib After Oral Administration in Humans, Contribution of the Metabolites to Pharmacological Activity

Olivier Nicolas, Patricia Moliner, Patrick Soubayrol, Olivier Vitse et autres

3 citationsClinical Drug Investigation

Accès ouvert 2020 articleOpenAlex

IMI – Oral biopharmaceutics tools project – Evaluation of bottom-up PBPK prediction success part 4: Prediction accuracy and software comparisons with improved data and modelling strategies

Amais Ahmad, Xavier Pépin, Leon Aarons, Yuya Wang et autres

40 citationsEuropean Journal of Pharmaceutics and Biopharmaceutics

2018 articleOpenAlex

Use of PBPK modeling for drug–drug interactions prediction of rifapentine on other drugs by induction of CYP3A4/5 and CYP2B6

Olivier Nicolas, Hélène Vermet, Brigitte Demers, Xavier Boulenc et autres

0 citationsDrug Metabolism and Pharmacokinetics

Accès ouvert 2017 articleOpenAlex

Discovery of Novel Allosteric HCV NS5B Inhibitors. 2. Lactam-Containing Thiophene Carboxylates

Pan Li, Warren A. Dorsch, David Lauffer, Darius Bilimoria et autres

12 citationsACS Medicinal Chemistry Letters

Accès ouvert 2017 articleOpenAlex

A Comparative Study of Milestones for Featuring GUI Prototyping Tools

Thiago Rocha Silva, Jean-Luc Hak, Marco Winckler, Olivier Nicolas

14 citationsJournal of Software Engineering and Applications

Accès ouvert 2016 articleOpenAlex

IMI – Oral biopharmaceutics tools project – Evaluation of bottom-up PBPK prediction success part 2: An introduction to the simulation exercise and overview of results

Alison Margolskee, Adam S. Darwich, Xavier Pépin, Leon Aarons et autres

68 citationsEuropean Journal of Pharmaceutical Sciences

Accès ouvert 2016 articleOpenAlex

IMI – Oral biopharmaceutics tools project – Evaluation of bottom-up PBPK prediction success part 3: Identifying gaps in system parameters by analysing In Silico performance across different compound classes

Adam S. Darwich, Alison Margolskee, Xavier Pépin, Leon Aarons et autres

45 citationsEuropean Journal of Pharmaceutical Sciences

Accès ouvert 2016 articleOpenAlex

Discovery of Novel Thiophene-Based, Thumb Pocket 2 Allosteric Inhibitors of the Hepatitis C NS5B Polymerase with Improved Potency and Physicochemical Profiles

John J. Court, Carl Poisson, Andrzej Ardzinski, Darius Bilimoria et autres

13 citationsJournal of Medicinal Chemistry

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