Manon M. Oude Nijhuis

Effects of a specific synbiotic blend on fecal short-chain fatty acids and gut inflammation in cow's milk-allergic children receiving amino acid–based formula during early life: results of a randomized controlled trial (PRESTO study)

Pantipa Chatchatee, Annelot C. Breedveld, Simone R. B. M. Eussen, Anna H Nowak-Wegrzyn et autres

M-16V] (AAF-S) beneficially impacts the gut microbiome of infants with cow's milk allergy (CMA). We assessed the effect of consuming AAF with or without synbiotics by children with CMA for 12 months on their fecal (branched) short-chain fatty acids (SCFA/BCFA) concentrations, and …

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Tolerance development in cow's milk‐allergic children receiving amino acid‐based formula with synbiotics: 36‐Months follow‐up of a randomized controlled trial (PRESTO Study)

Pantipa Chatchatee, Anna H Nowak-Wegrzyn, Lars Lange, Suwat Benjaponpitak et autres

The objective of the present study is to assess the rates of acquired tolerance to cow's milk (CM) after 36 months in subjects who consumed amino acid-based formula with synbiotics (AAF-S) or amino acid-based formula without synbiotics (AAF) during a 1-year intervention …

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Assessment of infant outgrowth of cow’s milk allergy in relation to the faecal microbiome and metaproteome

Diana M. Hendrickx, Ran An, Sjef Boeren, Sumanth Kumar Mutte et autres

Previous studies provide evidence for an association between modifications of the gut microbiota in early life and the development of food allergies. We studied the faecal microbiota composition (16S rRNA gene amplicon sequencing) and faecal microbiome functionality (metaproteomics) in a cohort of …

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Tolerance development in cow’s milk–allergic infants receiving amino acid–based formula: A randomized controlled trial

Pantipa Chatchatee, Anna H Nowak-Wegrzyn, Lars Lange, Suwat Benjaponpitak et autres

BACKGROUND: Tolerance development is an important clinical outcome for infants with cow's milk allergy. OBJECTIVE: This multicenter, prospective, randomized, double-blind, controlled clinical study (NTR3725) evaluated tolerance development to cow's milk (CM) and safety of an amino acid-based formula (AAF) including synbiotics (AAF-S) …

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A specific synbiotic-containing amino acid-based formula in dietary management of cow’s milk allergy: a randomized controlled trial

Adam Tobias Fox, Harm Wopereis, Marleen T. J. van Ampting, Manon M. Oude Nijhuis et autres

Here we report follow-up data from a double-blind, randomized, controlled multicenter trial, which investigated fecal microbiota changes with a new amino acid-based formula (AAF) including synbiotics in infants with non-immunoglobulin E (IgE)-mediated cow’s milk allergy (CMA). Subjects were randomized to receive test …

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A synbiotic-containing amino-acid-based formula improves gut microbiota in non-IgE-mediated allergic infants

David C. A. Candy, Marleen T. J. van Ampting, Manon M. Oude Nijhuis, Harm Wopereis et autres

BackgroundPrebiotics and probiotics (synbiotics) can modify gut microbiota and have potential in allergy management when combined with amino-acid-based formula (AAF) for infants with cow's milk allergy (CMA).MethodsThis multicenter, double-blind, randomized controlled trial investigated the effects of an AAF-including synbiotic blend on percentages …

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Abstracts from the Food Allergy and Anaphylaxis Meeting 2016

G. Pouessel, Claire Claverie, Julien Labreuche, Jean‐Marie Renaudin et autres

Introduction: Incidence of anaphylaxis is increasing.Data regarding anaphylaxis mortality are limited, but conflicting.Our objective was to document anaphylaxis mortality rate (deaths per million population), time trends and specificities according to triggers (iatrogenic, venom, food, unknown), age groups, sex and geographical regions (North …

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Gut Microbiota Composition of Non-IgE Mediated Cow's Milk Allergic Infants before and after Dietary Management with a Synbiotics-Supplemented Amino Acid-Based Formula

Harm Wopereis, Marleen T. J. van Ampting, David C. A. Candy, Diego Giampietro Peroni et autres

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Synbiotics‐supplemented amino acid‐based formula supports adequate growth in cow's milk allergic infants

A. Wesley Burks, Lucien F. Harthoorn, Marleen T. J. van Ampting, Manon M. Oude Nijhuis et autres

BACKGROUND: Children with cow's milk allergy (CMA) are at risk for inadequate nutritional intake and growth. Dietary management of CMA, therefore, requires diets that are not only hypoallergenic but also support adequate growth in this population. This study assessed growth of CMA …

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Levels of extra domain A containing fibronectin in human atherosclerotic plaques are associated with a stable plaque phenotype

J. Karlijn van Keulen, Dominique PV de Kleijn, Manon M. Oude Nijhuis, Els Busser et autres

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Peptidoglycan Increases Firm Adhesion of Monocytes under Flow Conditions and Primes Monocyte Chemotaxis

Manon M. Oude Nijhuis, Gerard Pasterkamp, Nienke I. Sluis, Dominique P.V. de Kleijn et autres

The Toll-like receptor (TLR) 2/nucleotide-binding oligomerization domain ligand peptidoglycan (PG) has been shown to be present in macrophage-rich regions within atherosclerotic lesions, and stimulation of TLR2 promotes atherosclerotic plaque and intima formation in in vivo mouse models. We determined the effect of …

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Conference Calendar

XU Shi-wen, David J. Abraham, Domingos S.R. Souza, Soo Kyoung Choi et autres