Floriana Centritto

Association of proinflammatory diet with low-grade inflammation: results from the Moli-sani study

Nitin Shivappa, Marialaura Bonaccio, James R. Hébert, Augusto Di Castelnuovo et autres

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Serum vitamin D deficiency and risk of hospitalization for heart failure: Prospective results from the Moli-sani study

Simona Costanzo, Amalia De Curtis, Augusto Di Castelnuovo, Mariarosaria Persichillo et autres

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Reduced mortality risk by a polyphenol-rich diet: An analysis from the Moli-sani study

George Pounis, Simona Costanzo, Marialaura Bonaccio, Augusto Di Castelnuovo et autres

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Moderate Alcohol Consumption Is Associated With Lower Risk for Heart Failure But Not Atrial Fibrillation

Augusto Di Castelnuovo, Simona Costanzo, Marialaura Bonaccio, Livia Rago et autres

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Fish intake is associated with lower cardiovascular risk in a Mediterranean population: Prospective results from the Moli-sani study

Marialaura Bonaccio, Emilia Ruggiero, Augusto Di Castelnuovo, Simona Costanzo et autres

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Polymerase ε (POLE) ultra-mutation in uterine tumors correlates with T lymphocyte infiltration and increased resistance to platinum-based chemotherapy in vitro

Stefania Bellone, Eliana Bignotti, Silvia Lonardi, Francesca Ferrari et autres

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Novel Axl-driven signaling pathway and molecular signature characterize high-grade ovarian cancer patients with poor clinical outcome

Katia Rea, Patrizia Pinciroli, Marialuisa Sensi, Federica Alciato et autres

// Katia Rea 1 , Patrizia Pinciroli 2 , Marialuisa Sensi 2 , Federica Alciato 3 , Brigitte Bisaro 4 , Ludmila Lozneanu 5 , Francesco Raspagliesi 6 , Floriana Centritto 2 , Sara Cabodi 4 , Paola Defilippi 4 , Gian …

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Clostridium perfringens enterotoxin C ‐terminal domain labeled to fluorescent dyes for in vivo visualization of micrometastatic chemotherapy‐resistant ovarian cancer

Emiliano Cocco, Erik M. Shapiro, Sara Gasparrini, Salvatore Lopez et autres

Identification of micrometastatic disease at the time of surgery remains extremely challenging in ovarian cancer patients. We used fluorescence microscopy, an in vivo imaging system and a fluorescence stereo microscope to evaluate fluorescence distribution in Claudin-3- and -4-overexpressing ovarian tumors, floating tumor …

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All-trans-retinoic Acid Modulates the Plasticity and Inhibits the Motility of Breast Cancer Cells

Adriana Zanetti, Roberta Affatato, Floriana Centritto, Maddalena Fratelli et autres

All-trans-retinoic acid (ATRA) is a natural compound proposed for the treatment/chemoprevention of breast cancer. Increasing evidence indicates that aberrant regulation of epithelial-to-mesenchymal transition (EMT) is a determinant of the cancer cell invasive and metastatic behavior. The effects of ATRA on EMT are …

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Polymerase ε (POLE) ultra-mutated tumors induce robust tumor-specific CD4+ T cell responses in endometrial cancer patients

Stefania Bellone, Floriana Centritto, Jonathan Black, Carlton L. Schwab et autres

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Cellular and molecular determinants of all‐trans retinoic acid sensitivity in breast cancer: Luminal phenotype and RARα expression

Floriana Centritto, Gabriela Paroni, Marco Bolis, Silvio Ken Garattini et autres

Forty-two cell lines recapitulating mammary carcinoma heterogeneity were profiled for all-trans retinoic acid (ATRA) sensitivity. Luminal and ER(+) (estrogen-receptor-positive) cell lines are generally sensitive to ATRA, while refractoriness/low sensitivity is associated with a Basal phenotype and HER2 positivity. Indeed, only 2 Basal …

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Improved survival of patients with hypermutation in uterine serous carcinoma

Alessandro D. Santin, Stefania Bellone, Floriana Centritto, Joseph Schlessinger et autres

•Uterine serous carcinoma (USC) is an aggressive subtype of endometrial cancer.•Mutations in DNA polymerase ε gene (POLE) are detected in a subset of USC and confer a strong mutator phenotype.•USC patients diagnosed with POLE mutations experience a significantly better prognosis.

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