Troy Grennan

Doxycycline pre-exposure prophylaxis (doxyPrEP) versus doxycycline post-exposure prophylaxis (doxyPEP) for preventing bacterial sexually transmitted infections in gay, bisexual, and other men who have sex with men (GBM) and transgender women: protocol for a randomized non-inferiority trial

Maya Tharp, Mark Hull, Ann N. Burchell, Darrell H. Tan et autres

The global incidence of bacterial sexually transmitted infections (STIs), including syphilis, gonorrhea, and chlamydia, is rising at an unprecedented rate. This trend is particularly concerning among gay, bisexual, and other men who have sex with men (GBM) and transgender women, who experience …

ca, us, th (code pays fourni par la source)

Human Papillomavirus Vaccine Effectiveness Against Prevalent Human Papillomavirus by Age, Years Sexually Active Before Vaccination, and HIV Status in Gay, Bisexual, and Other Men Who Have Sex With Men, 2019–2021

Pranamika Khayargoli, Daniel Grace, Joseph Cox, Alexandra de Pokomandy et autres

BACKGROUND: We compared the prevalence of vaccine-preventable anal human papillomavirus (HPV) types among gay, bisexual, and other men who have sex with men (GBM) living in large cities in Canada from 2019 to 2021 by age and HIV status. METHODS: Sexually-active GBM …

ca, se, gb (code pays fourni par la source)

Anal cancer screening: introduction into routine clinical care for key populations

Troy Grennan, Tamzin Cuming

ca, gb (code pays fourni par la source)

Application of the Cascade of Care Framework to Guide Evidence-Informed Implementation of Anal Cancer Screening Guidelines

Ann N. Burchell, Troy Grennan, Christine Fahim, Dina Gaid et autres

Most squamous cell carcinomas of the anus, or anal cancers, are attributable to persistent infection with the human papillomavirus (HPV), analogous to cervical cancer. Although rare in the general population, rates of anal cancer are high among people with immune-compromising conditions or …

ca (code pays fourni par la source)

HPV prevalence, vaccination coverage and intention to get vaccinated among gay, bisexual, and other men who have sex with men: Evaluation of Quebec’s (Canada) HPV vaccination program

Chantal Sauvageau, Alain Fourmigue, Manale Ouakki, Gilles Lambert et autres

ABSTRACT Objectives In Quebec, Canada, vaccination against human papillomavirus (HPV) has been publicly-funded since January 2016 for gay, bisexual, and other men who have sex with men (GBM) aged ≤26 years. The study aimed to analyze data collected in Greater Montreal (Engage …

ca, Côte d’Ivoire, us (code pays fourni par la source)

Incidence and risk factors of C. trachomatis , N. gonorrhoeae and syphilis among a cohort of urban Canadian gay, bisexual and other men who have sex with men, 2017–2023: informing the potential impact of doxycycline prophylaxis

Gilles Lambert, Alain Fourmigue, Milada Dvořáková, Erica E M Moodie et autres

OBJECTIVES: and syphilis (sexually transmitted infections (STIs)) among gay, bisexual and other men who have sex with men (GBM). There is a need to identify prescribing criteria that maximise the number of STIs averted while minimising excessive use. DESIGN: In this prospective …

ca (code pays fourni par la source)

Trends in the Incidence of HPV-Associated Anal Cancer by Risk Group, 1990-2019: A Population-Based Cohort Study in British Columbia, Canada

Amit K. Gupta, Aidan Ablona, Theodora B. Consolacion, Sofia R. Bartlett et autres

BACKGROUND: Anal squamous cell carcinoma caused by human papillomavirus disproportionately affects people living with human immunodeficiency virus (HIV; PLWH), particularly gay, bisexual, and other men who have sex with men (GBM). New guidelines recommend screening and treatment of precancerous lesions. We aimed …

ca, se, gb (code pays fourni par la source)

Development and Validation of a Revised Multidimensional Digital Health Literacy Scale: Secondary Analysis Using Cross-Sectional Data From the 2022 GetCheckedOnline Community Survey In British Columbia, Canada

Ihoghosa Osamuyi Iyamu, Pierce Gorun, Hsiu-Ju Chang, Rodrigo Sierra-Rosales et autres

Background Digital technologies are reshaping health care, making digital health literacy (DHL) a critical competency for navigating online health information. Although widely conceived and measured as a unidimensional measure of DHL, the literature increasingly supports a multidimensional framing of the eHealth Literacy …

ca, us (code pays fourni par la source)

Complex role of digital health literacy in awareness and use of digital sexually transmitted and blood-borne infections testing: a structural equation modelling analysis of the 2022 GetCheckedOnline survey

Ihoghosa Osamuyi Iyamu, Pierce Gorun, Sofia R. Bartlett, Geoffrey R. McKee et autres

BACKGROUND: Although digital health literacy (DHL) is recognised as a determinant of access to digital sexually transmitted and blood-borne infection (STBBI) testing, empirical evidence about its contribution to access disparities remains limited. We applied multidimensional DHL measures to examine inequities in awareness …

ca, us (code pays fourni par la source)

Quadrivalent HPV Vaccine Evaluation Study with Addition of the Nonavalent Vaccine (QUEST-ADVANCE): protocol of an observational cohort study

Marit Middeldorp, Robine Donken, Aarthi Nirmal, Brenda M. Smith et autres

INTRODUCTION: The Quadrivalent human papillomavirus (HPV) Vaccine Evaluation Study with Addition of the Nonavalent Vaccine Study (QUEST-ADVANCE) aims to provide insight into the long-term immunogenicity and effectiveness of one, two and three HPV vaccine doses. Here, we describe the protocol for QUEST-ADVANCE. …

nl, ca (code pays fourni par la source)

Impact of doxycycline pre-exposure prophylaxis (doxyPrEP) for sexually transmitted infections on the microbiome of men who have sex with men on HIV PrEP

Samantha Knodel, Leighanne R. Main, Marlon DeLeon, Alana Lamont et autres

Doxycycline pre-exposure prophylaxis (doxyPrEP) has shown potential in preventing bacterial sexually transmitted infections, but the impact on the microbiome is unknown. This study assessed rectal microbiome changes over 48 weeks in 41 participants on HIV PrEP (tenofovir disoproxil fumarate/emtricitabine) enrolled in an …

us, ca, se (code pays fourni par la source)

Development and Validation of a Revised Multidimensional Digital Health Literacy Scale: Secondary Analysis Using Cross-Sectional Data From the 2022 GetCheckedOnline Community Survey In British Columbia, Canada (Preprint)

Ihoghosa Osamuyi Iyamu, Pierce Gorun, Hsiu-Ju Chang, Rodrigo Sierra-Rosales et autres

BACKGROUND Digital technologies are reshaping health care, making digital health literacy (DHL) a critical competency for navigating online health information. Although widely conceived and measured as a unidimensional measure of DHL, the literature increasingly supports a multidimensional framing of the eHealth Literacy …