Santi Tofani

Review of: "Forecasting of the influence of physical fields on the metabolic nanocurrent in proteins"

Santi Tofani

Potential competing interests: No potential competing interests to

Magnetic fields and apoptosis: a possible mechanism

Santi Tofani

The potential therapeutic uses of electromagnetic fields (EMF), part of the nonionizing radiation spectrum, increase with time. Among them, those considering the potential antitumor effects exerted by the Magnetic Fields (MFs), part of the EMF entity, have gained more and more interest. …

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Role of an Atomic-Level-Based Approach for Improving Cancer Therapy

Santi Tofani

Looking at the atomic level of biological activity, the electron spin may be considered a key parameter, governing fundamental biological processes. Spin states have a major role in defining the structure, reactivity, magnetic and spectroscopic properties of a molecule. In the last …

The antitumor effect of static and extremely low frequency magnetic fields against nephroblastoma and neuroblastoma

Ling‐Qing Yuan, Can Wang, Kun Zhu, Huamei Li et autres

Certain magnetic fields (MF) have potential therapeutic antitumor effect whereas the underlying mechanism remains undefined. In this study, a well-characterized MF was applied to two common childhood malignancies, nephroblastoma and neuroblastoma. This MF has a time-averaged total intensity of 5.1 militesla (mT), …

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Hypofractionated Whole-Breast Radiotherapy and Concomitant Boost after Breast Conservation in Elderly Patients

Domenico Cante, Pierfrancesco Franco, Piera Sciacero, Giuseppe Girelli et autres

AIMS: To report the 5- and 10-year results of accelerated hypofractionated whole-breast radiotherapy (WBRT) with concomitant boost to the tumor bed in 83 consecutive patients with early breast cancer aged >70 years. METHODS: All patients were treated with breast conservation and hypofractionated …

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Image-guided Intensity-modulated Radiotherapy for Prostate Cancer Employing Hypofractionation and Simultaneous Integrated Boost: Results of a Consecutive Case Series with Focus on Erectile Function.

Giuseppe Girelli, Pierfrancesco Franco, Piera Sciacero, Domenico Cante et autres

AIM: To report on clinical outcomes of prostate cancer patients treated with hypofractionated radiotherapy employing a simultaneous integrated boost strategy. PATIENTS AND METHODS: A consecutive series of 104 patients affected with prostate cancer was treated with intensity-modulated radiotherapy using a hypofractionated schedule …

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THE CONTRIBUTION OF INTERVENTIONAL CARDIOLOGY PROCEDURES TO THE POPULATION RADIATION DOSE IN A ‘HEALTH-CARE LEVEL I’ REPRESENTATIVE REGION

Andrea Peruzzo Cornetto, Stefania Aimonetto, Francesco Pisano, Marcello Giudice et autres

This study evaluates per-procedure, collective and per capita effective dose to the population by interventional cardiology (IC) procedures performed during 2002-11 at the main hospital of Aosta Valley Region that can be considered as representative of the health-care level I countries, as …

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Electromagnetic Energy as a Bridge Between Atomic and Cellular Levels in the Genetics Approach to Cancer Treatment

Santi Tofani

Literature on magnetic fields (MF) and gene expression, as well as on DNA damage, supports the hypothesis that electromagnetic energy may act at atomic level influencing genetic stability. According to quantum physics, MF act on the interconversion of singlet and triplet spin …

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Bilateral Breast Radiation Delivered with Static Angle Tomotherapy (TomoDirect): Clinical Feasibility and Dosimetric Results of a Single Patient

Pierfrancesco Franco, F. Migliaccio, Paolo Torielli, Piera Sciacero et autres

We herein report on a case of synchronous bilateral breast cancer patient undergoing adjuvant intensity-modulated whole breast with static angle tomotherapy (TomoDirect). The patient was treated with a hypofractionated schedule employing a simultaneous integrated boost approach. Radiotherapy schedule was 45 Gy/20 fractions …

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Cerebellar glioblastoma multiforme in an adult woman.

Piera Sciacero, Giuseppe Girelli, Domenico Cante, Pierfrancesco Franco et autres

AIMS AND BACKGROUND: Glioblastoma multiforme (GBM) is the most frequent primary central nervous system malignancy in adults, accounting for 50% of all primary intracranial malignancies. GBM mostly arises within the cerebral hemispheres and frequently affects patients in the fifth and sixth decades …

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Palliative Radiotherapy for Painful Bone Metastases from Solid Tumors Delivered with Static Ports of Tomotherapy (TomoDirect): Feasibility and Clinical Results

Pierfrancesco Franco, F. Migliaccio, Veronica Angelini, Domenico Cante et autres

PURPOSE: To evaluate the feasibility and response to palliative radiotherapy delivered with static ports of tomotherapy--TomoDirect (TD) in patients affected with painful bone metastases from solid tumors. METHODS: A prospective cohort of 130 patients (185 osseous lesions) was treated between 2010 and …

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Palliative Radiation Therapy for Painful Bone Metastases From Solid Tumors Delivered With Static Ports of Tomotherapy

P. Franco, F. Migliaccio, Paolo Torielli, Cecilia Arrichiello et autres

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