Alicia Isabel Pérez‐Lorente

An engineered bacterial symbiont maps micron-scale sugar gradients in the honeybee gut

Audam Chhun, Andrew Quinn, Alicia Isabel Pérez‐Lorente, Théodora Steiner et autres

The honeybee gut microbiota plays a key role in shaping host health and susceptibility to disease. Yet, the nutrient environment it experiences within the gut remains poorly characterized. In particular, little is known about the spatial distribution of nutrients across the microbial …

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Flow cytometry FCS files

Audam Chhun, Alicia Isabel Pérez‐Lorente

FCS files underyling figures Fig. 2a and S5 Fig of the publication 'An engineered bacterial symbiont maps micron-scale sugar gradients in the honeybee gut'.

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Flow cytometry FCS files

Audam Chhun, Alicia Isabel Pérez‐Lorente

FCS files underyling figures Fig. 2a and S5 Fig of the publication 'An engineered bacterial symbiont maps micron-scale sugar gradients in the honeybee gut'.

ch (code pays fourni par la source)

Cooperative siderophore use stabilizes a protective leaf microbiome

Paolo Stincone, Lukas M. Braun, Caner Bağcı, Marcelo Navarro-Díaz et autres

Abstract Plant-associated microbial communities provide crucial protection against pathogens. Specialized metabolites play key roles in plant-microbe and microbe-microbe interactions and, ultimately, in plant health; however, the molecular mechanisms underlying their plant-protecting properties remain largely unknown. Nutrient deficiency (e.g., iron) on leaf surfaces …

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An engineered bacterial symbiont maps micron-scale sugar gradients in the honeybee gut

Audam Chhun, Andrew Quinn, Alicia Isabel Pérez‐Lorente, Théodora Steiner et autres

Abstract The honeybee gut microbiota plays a key role in shaping host health and susceptibility to disease. Yet, the nutrient environment it experiences within the gut remains poorly characterized. In particular, little is known about the spatial distribution of nutrients across the …

ch (code pays fourni par la source)

Engineering the T6SS of Pseudomonas for targeted delivery of antibacterial and antifungal effectors

Alicia Isabel Pérez‐Lorente, Mario Araujo-Garrido, Antonio de Vicente, Diego Romero et autres

BACKGROUND: Bacteria employ diverse molecular systems, such as the type VI secretion system (T6SS) to outcompete other microorganisms and adapt to ecological niches. The T6SS is a versatile nanomachine capable of delivering toxic effectors into neighboring cells, providing advantages in bacterial interactions. …

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The offensive role of the Bacillus extracellular matrix in driving metabolite-mediated dialogue and adaptive strategies with pathogenic fungi

Alicia Isabel Pérez‐Lorente, Carlos Molina‐Santiago, David Vela‐Corcía, Paolo Stincone et autres

Abstract Bacterial□fungal interactions have traditionally been attributed to secondary metabolites, but the role of the bacterial extracellular matrix (ECM) in shaping these relationships has remained unclear. Here, we demonstrate that the ECM protein TasA is a key mediator in the antagonistic interaction …

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Offensive role of the Bacillus extracellular matrix in driving metabolite-mediated dialog and adaptive strategies with the fungus Botrytis

Alicia Isabel Pérez‐Lorente, Carlos Molina‐Santiago, David Vela‐Corcía, Paolo Stincone et autres

Bacterial-fungal interactions have traditionally been attributed to secondary metabolites, but the role of the bacterial extracellular matrix in shaping these relationships has remained unclear. Here, we demonstrate that the extracellular matrix protein TasA is a key mediator in the antagonistic interaction between …

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Engineering the T6SS of Pseudomonas for targeted delivery of antibacterial and antifungal effectors

Alicia Isabel Pérez‐Lorente, Mario Araujo-Garrido, Antonio de Vicente, Diego Romero et autres

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Cyclo(Pro-Tyr) elicits conserved cellular damage in fungi by targeting the [H+]ATPase Pma1 in plasma membrane domains

David Vela‐Corcía, Jesús Hierrezuelo, Alicia Isabel Pérez‐Lorente, Paolo Stincone et autres

Bioactive metabolites play a crucial role in shaping interactions among diverse organisms. In this study, we identified cyclo(Pro-Tyr), a metabolite produced by Bacillus velezensis, as a potent inhibitor of Botrytis cinerea and Caenorhabditis elegans, two potential cohabitant eukaryotic organisms. Based on our …

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Unravelling the impact of environmental factors in shaping plant microbiomes

Alicia Isabel Pérez‐Lorente, Diego Romero, Carlos Molina‐Santiago

This article emphasizes the significant role of environmental factors in shaping the plant microbiome, highlighting how bacterial and fungal communities influence plant responses to water stress, and how environmental factors shape fungal communities in crops. Furthermore, recent studies describe how different genotypes …

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microbeMASST: a taxonomically informed mass spectrometry search tool for microbial metabolomics data

Simone Zuffa, Robin Schmid, Anelize Bauermeister, Paulo Wender Portal Gomes et autres

microbeMASST, a taxonomically informed mass spectrometry (MS) search tool, tackles limited microbial metabolite annotation in untargeted metabolomics experiments. Leveraging a curated database of >60,000 microbial monocultures, users can search known and unknown MS/MS spectra and link them to their respective microbial producers …

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