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Orly Leiva, Olivia Liu, Steven Soo, Andrew S. Palmer et autres
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Orly Leiva, Steven Soo, Olivia Liu, Justin A. Kahla et autres
Background: Myeloproliferative neoplasms (MPNs), including essential thrombocythemia (ET), polycythemia vera (PV), and myelofibrosis (MF), are chronic leukemias associated with cardiovascular (CV) disease (CVD), including pulmonary hypertension (PH). Prior studies utilizing echocardiography for identifying PH in MPNs have suggested an association between PH …
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Orly Leiva, Steven Soo, Olivia Liu, Victor You et autres
Abstract Introduction: Myeloproliferative neoplasms (MPNs), which include essential thrombocythemia (ET), polycythemia vera (PV), and myelofibrosis (MF), are a diverse group of hematopoietic stem cell disorders associated with an increased risk of cardiovascular disease (CVD), including arterial thrombosis and heart failure (HF). Elevated …
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Orly Leiva, Steven Soo, Olivia Liu, Victor You et autres
Abstract Introduction Myelofibrosis (MF) is an advanced phenotype of Philadelphia chromosome-negative myeloproliferative neoplasm (MPN) characterized by extramedullary hematopoiesis (EMH). Moreover, patients with MF are at increased risk of cardiovascular disease (CVD), especially heart failure (HF) and pulmonary hypertension (PH), which occur more …
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Orly Leiva, Steven Soo, Olivia Liu, Victor You et autres
Abstract Introduction: Myeloproliferative neoplasms (MPNs), which include essential thrombocythemia (ET), polycythemia vera (PV), and myelofibrosis (MF), are a group of hematopoietic stem cell disorders associated with an increased risk of cardiovascular disease (CVD), including arterial thrombosis and heart failure (HF). Statin use …
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Orly Leiva, Olivia Liu, Victor You, Steven Soo et autres
Abstract Introduction: Pulmonary hypertension (PH) is associated with Philadelphia-chromosome negative myeloproliferative neoplasms (MPNs. In prior studies utilizing transthoracic echocardiography (TTE) to screen for PH, PH was associated with increased risk of hematologic progression among patients with MPN. However, PH is a heterogenous …
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Orly Leiva, Olivia Liu, Anthony Kanelidis, Stanley Swat et autres
Patients with myeloproliferative neoplasms (MPNs) are at increased risk for cardiovascular disease. Although thrombosis is a well-recognized complication, emerging evidence indicates that nonthrombotic conditions, including heart failure (HF) and pulmonary hypertension (PH), are also prevalent and associated with adverse cardiovascular and hematologic …
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Albert Leng, Preetham Bachina, Olivia Liu, Benjamin L. Shou et autres
In-hospital mortality after venoarterial extracorporeal membrane oxygenation (VA-ECMO) remains high. This study compared the performance of the Survival after Venoarterial ECMO (SAVE) score with machine learning (ML) models incorporating rich electronic medical record data to evaluate survival for patients on VA-ECMO support. …
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Orly Leiva, Steven Soo, Olivia Liu, Nathaniel R. Smilowitz et autres
Pulmonary hypertension (PH) is a frequent complication of Philadelphia-negative myeloproliferative neoplasms (MPN), including essential thrombocythemia (ET), polycythemia vera (PV), and myelofibrosis (MF). However, its prognostic significance is understudied. We, therefore, aimed to evaluate the effect of PH identified by echocardiography on the …
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Olivia Liu, Robin Ortiz, Jennifer Woo Baidal, Kristyn A. Pierce et autres
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Andrew Ly, Syed A. Ahmad, Olivia Liu, Shi Nan Feng et autres
Immune thrombocytopenia (ITP) and immune-mediated thrombotic thrombocytopenic purpura (iTTP) are associated with haemostatic abnormalities. However, data on stroke including intracranial haemorrhage (ICH) and acute ischaemic stroke (AIS) in paediatric ITP and iTTP are limited. We aimed to primarily investigate the prevalence of …
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Syed A. Ahmad, Olivia Liu, Amy Feng, Andrew Kalra et autres
BACKGROUND: There is an emerging understanding of the increased risk of stroke in patients with immune thrombocytopenic purpura (ITP) and immune thrombotic thrombocytopenic purpura (iTTP). We aimed to determine the prevalence and characteristics of acute ischemic stroke (AIS) and intracranial hemorrhage (ICH) …
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