Katarzyna Życińska

Complement C3c Reflects Acute-Phase Response but Not Clinical Phenotype in Systemic Sclerosis: A Cross-Sectional Study

Jakub Trefler, Anna Pasierb, Lidia Lech, Hubert Czaplicki et autres

This study evaluated routinely measured serum complement C3c (C3c) and complement C4 (C4) in relation to systemic inflammation, clinical and immunological phenotypes, and patient-reported outcomes (PROs) in systemic sclerosis (SSc). Seventy SSc patients fulfilling the 2013 American College of Rheumatology/European League Against …

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Benralizumab as a steroid-sparing rescue therapy in ANCA-negative eosinophilic granulomatosis with polyangiitis: real-world experience from three cases and review of the literature

Agata Sebastian, Joanna Kosałka-Węgiel, Katarzyna Życińska, Bogdan Kolarz et autres

Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare small-vessel vasculitis driven by type 2 inflammation, frequently associated with severe asthma, eosinophilia, and multiorgan involvement. Despite conventional immunosuppressive therapy, many patients remain steroid-dependent or refractory. Benralizumab, an anti-IL-5 receptor monoclonal antibody inducing rapid …

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Zmiany ogniskowe tarczycy

Dorota Szydlarska, Katarzyna Życińska, Alicja Jakubowska, Andrzej Śliwczyński

Capillaroscopic patterns are associated with interstitial lung disease, skin fibrosis, anti-Th/To antibodies and quality of life in systemic sclerosis: a prospective cross-sectional study

Jakub Trefler, Anna Pasierb, Lidia Lech, Hubert Czaplicki et autres

Background Capillaroscopic patterns in systemic sclerosis (SSc) are routinely assessed by nailfold videocapillaroscopy (NVC), yet their broader clinical relevance remains incompletely defined. Methods In a prospective cross-sectional study of 70 SSc patients, we evaluated associations between NVC patterns and key clinical domains: …

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Associations of serum CA 15–3 with interstitial lung disease, PM/Scl100 antibodies and other disease characteristics in systemic sclerosis

Jakub Trefler, Anna Pasierb, Lidia Lech, Katarzyna Życińska

To investigate associations of serum CA 15-3 with interstitial lung disease (ILD), anti-PM/Scl100 antibodies, and other features in systemic sclerosis (SSc). We enrolled 59 SSc patients fulfilling 2013 ACR/EULAR criteria. CA 15-3 levels were compared between HRCT-confirmed ILD and non-ILD groups. Associations …

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Lower total serum Immunoglobulin G is associated with impaired patient-reported health-related quality of life in systemic sclerosis: a prospective cross-sectional study

Jakub Trefler, Anna Pasierb, Lidia Lech, Katarzyna Życińska

Systemic sclerosis (SSc) is a connective tissue disease characterized by immune dysregulation, fibrosis, and vasculopathy, frequently resulting in substantial impairment in health-related quality of life (HRQoL). Total serum immunoglobulin G (IgG), a central component of adaptive humoral immunity, may reflect cumulative disease …

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Serum CA 15-3 associations with interstitial lung disease, PM/Scl100 antibodies and other characteristics in systemic sclerosis: an exploratory cross-sectional study

Jakub Trefler, Anna Pasierb, Lidia Lech, Katarzyna Życińska

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Leczenie biologiczne chorób reumatycznych

Włodzimierz Samborski, Katarzyna Gajewicz-Sawicka, Bogna Grygiel‐Górniak, Zofia Guła et autres

Diagnosis and treatment of Fabry disease. Expert Opinion of the Polish Cardiac Society and the Polish Forum for Fabry Disease

Piotr Podolec, Przemysław Mitkowski, Agnieszka Słowik, Agnieszka Gala‐Błądzińska et autres

Fabry disease (FD) belongs to the group of lysosomal storage diseases (LSD), characterized by insufficient enzyme activity responsible for the intra-lysosomal breakdown of various substrates. The result is an uncontrolled accumulation of by-products of cellular metabolism. Lysosomal storage diseases are inherited and …

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Muscle damage in growers

Anna Pasierb, Katarzyna Życińska, Hubert Czaplicki

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No progression of radiographic changes in the sacroiliac joints of a patient with non-radiographic axial spondyloarthritis treated with secukinumab: A 6-year observation

Jakub Trefler, Karol Skopiński, Hubert Czaplicki, Katarzyna Życińska

krzyżowo-biodrowych u pacjentki z nieradiograficzną spondyloartropatią osiową leczonej sekukinumabem -6-letnia obserwacja

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Larynx infiltration is not always a neoplasm – ultrarare rheumatological cause of hoarseness

Jagoda Kruszewska, Katarzyna Życińska

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