Lawrence Obado Osuwat

Assessment of Arsenic levels in borehole-water and human biological samples in Amuria district of Eastern Uganda

Lawrence Fred Sembajwe, Lawrence Obado Osuwat, Joshua Nfambi, Joash Okoboi et autres

Background Arsenic is one of the major toxic elements in the environment and is also known to be carcinogenic, with several other health side effects in human beings. Due to the lack of a sufficient supply of treated piped water across Uganda, …

Ouganda, no (code pays fourni par la source)

Community perspectives and insights into cancer surveillance, prevention, and research: an engaged participatory approach to cancer epidemiology research in remote areas of Northeastern Uganda

Ronald Opito, Alfred Jatho, Wilber Sabiiti, Hellen Akurut et autres

BACKGROUND: There is limited research on cancer screening, prevention and treatment in the remote areas of Northeastern Uganda. Specifically, there is limited research presenting cancer control stakeholder perspectives in remote settings, whereas stakeholders’ perspectives are critical for an engaged participatory approach to …

Ouganda, gb (code pays fourni par la source)

Association between non-high-density lipoprotein cholesterol and non-alcoholic fatty liver disease among people living with HIV on dolutegravir-based antiretroviral therapy: A cross-sectional study in Southwestern Uganda

Charles Nkubi Bagenda, Carol Nantongo, Elastus Ssemwanga, Michael Junior Mugisa et autres

OBJECTIVE: Non-high-density lipoprotein cholesterol, an aggregate marker of atherogenic lipoproteins, has been implicated in metabolic dysfunction and may predict non-alcoholic fatty liver disease risk. Our study investigated the association between non-high-density lipoprotein cholesterol and non-alcoholic fatty liver disease among people living with …

Ouganda, Tanzanie, Kenya (code pays fourni par la source)

Association Between High Serum Alanine Aminotransferase to High Density Lipoprotein Cholesterol Ratio and Metabolic Syndrome among People Living with HIV on Dolutegravir-Based ART in South-Western Uganda

Charles Nkubi Bagenda, Carol Nantongo, Michael Junior Mugisa, Blendar Ainebyoona et autres

BackgroundSerum Alanine aminotransferase to High density lipoprotein cholesterol ratio (ALT-to-HDL-C ratio) has been identified as a significant predictor of non-alcoholic fatty liver disease, a hepatic manifestation of metabolic syndrome. This study investigated the association between serum aminotransferases to high-density lipoprotein cholesterol ratios …

Ouganda (code pays fourni par la source)

Total cholesterol/high-density lipoprotein cholesterol ratio is a significant predictor of metabolic syndrome among people on dolutegravir-based antiretroviral therapy: A cross-sectional study in southwestern Uganda

Charles Nkubi Bagenda, Carol Nantongo, Elastus Ssemwanga, Michael Junior Mugisa et autres

ObjectiveThe total cholesterol/high-density lipoprotein cholesterol ratio is a predictor of nonalcoholic fatty liver disease-a hepatic manifestation of metabolic syndrome. This study investigated the association between total cholesterol/high-density lipoprotein cholesterol ratio and metabolic syndrome among people living with human immunodeficiency virus on dolutegravir-based …

Ouganda, us (code pays fourni par la source)

Association of high serum aspartate transaminase to high density lipoprotein-cholesterol ratio with probable dementia among people living with HIV on antiretroviral therapy in Southwestern Uganda

Charles Nkubi Bagenda, Hope Mudondo, Elastus Ssemwanga, Daniel Nzaramba et autres

Objectives: Previous studies present conflicting evidence on the relationship between hepatocellular damage biomarkers and dementia risk. While elevated serum transaminases have been associated with mild cognitive impairment, other studies link lower transaminase levels and reduced high-density lipoprotein-cholesterol levels to increased risk of …

Ouganda (code pays fourni par la source)

Dyslipidemia and Associated Factors Among People Living With HIV on Dolutegravir-Based Antiretroviral Therapy in Central Uganda

Flavia Timbigamba, Charles Nkubi Bagenda, Hendry Sembogga, Timothy Wasswa et autres

Introduction : Dolutegravir (DTG)-based antiretroviral therapy (ART) use has been associated with excessive weight gain, increasing the risk of dyslipidemias such as hypercholesterolemia. We assessed the prevalence of, and associated factors with dyslipidemia among adults on DTG-based ART. Materials and methods We …

Ouganda, us (code pays fourni par la source)

Association of High Tc/Hdl-C Ratio with Probable Dementia Among Elderly People: A Cross-Sectional Study

Dianah Ishimwe, Charles Nkubi Bagenda, Ruth Tushemerirwe, Jacinta Namugangu et autres

Ouganda (code pays fourni par la source)

A protein restricted diet induces a stable increased fat storage phenotype in flies

Oscar Hilary Asiimwe, John Rubaihayo, Sheu Oluwadare Sulaiman, Lawrence Obado Osuwat et autres

Scientific evidence has revealed possible confounders in diet induced obesity models of Drosophila melanogaster. High Sugar Diet (HSD) induction of obesity in flies has been associated with fly hyperosmolarity and glucotoxicity, while High Fat Diet (HFD) induction has been associated with lipotoxicity. …

Ouganda, cn, br, Rwanda, gb (code pays fourni par la source)

The practice of pilot/feasibility studies in informing the conduct of HIV related clinical trials in sub-Saharan Africa: A scoping review

Sylivia Nalubega, Lawrence Obado Osuwat, Catrin Evans, John Bosco Matovu

Introduction: Pilot/feasibility studies represent a fundamental phase of the research process and play a vital role in the preliminary planning of a full size HIV clinical trial. Published HIV clinical trial protocols were reviewed to establish the extent to which the proposed …

Ouganda, gb (code pays fourni par la source)

The Rise of SARS-CoV-2 Variants and the Role of Convalescent Plasma Therapy for Management of Infections

Mohamed Moubarak, Keneth Iceland Kasozi, ‏Helal F. Hetta, Hazem M. Shaheen et autres

Novel therapies for the treatment of COVID-19 are continuing to emerge as the SARS-Cov-2 pandemic progresses. PCR remains the standard benchmark for initial diagnosis of COVID-19 infection, while advances in immunological profiling are guiding clinical treatment. The SARS-Cov-2 virus has undergone multiple …

Égypte, Ouganda, gb, pk, iq, sa, cn (code pays fourni par la source)

Dietary Restriction Induces a Stable Metabolic Obesity Phenotype in Drosophila Melanogaster

Oscar Hilary Asiimwe, Sheu Oluwadare Sulaiman, Juma John Ochieng, David Onanyang et autres

Abstract ObjectiveChallenges associated with current nutritional models to induce obesity in Drosophila melanogaster created a rationale for this study. The objective of the study was to investigate biochemical changes associated with high-fat diet (HFD), high sucrose diet (HSD), and a protein-restricted diet …

us, Ouganda (code pays fourni par la source)