Ester Muñoz‐Aceituno

Pharmacogenetic biomarkers for secukinumab response in psoriasis patients in real‐life clinical practice

Ester Muñoz‐Aceituno, B. Butrón, María C. Ovejero‐Benito, Antonio Sahuquillo‐Torralba et autres

BACKGROUND: Prediction of the response to a biological treatment in psoriasis patients would allow efficient treatment allocation. OBJECTIVE: To identify polymorphisms associated with secukinumab response in psoriasis patients in a daily practice setting. METHODS: We studied 180 SNPs in patients with moderate-to-severe …

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[Articulo traducido] Inicio demorado de urticaria solar coexistente con urticaria crónica espontánea y erupción polimorfa lumínica

Alejandra Reolid, Ester Muñoz‐Aceituno, Pedro Rodríguez‐Jiménez, D. de Argila

demorado de urticaria solar coexistente con urticaria crónica espontánea y erupción polimorfa lumínica Delayed-onset Solar Urticaria Coexisting With Spontaneous Chronic Urticaria and Polymorphic Light Eruption Sr. Director:La urticaria solar (US) se caracteriza por la aparición inmediata de eritema y habones pruriginosos en …

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CNVs Associated with Different Clinical Phenotypes of Psoriasis and Anti-TNF-Induced Palmoplantar Pustulosis

Alejandra Reolid, Antonio Sahuquillo‐Torralba, Ancor Sanz‐García, Rafael Botella‐Estrada et autres

BACKGROUND: Psoriasis can present different phenotypes and could affect diverse body areas. In contrast to the high effectiveness of biological drugs in the treatment of trunk and extremities plaque psoriasis, in palmoplantar phenotypes and in plaque scalp psoriasis, these same drugs usually …

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33945 DNA copy number variations associated with different clinical phenotypes of psoriasis and paradoxical anti-TNF induced palmoplantar pustulosis

Ester Muñoz‐Aceituno, Alejandra Reolid, Antonio Sahuquillo‐Torralba

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Delayed-onset Solar Urticaria Coexisting With Spontaneous Chronic Urticaria and Polymorphic Light Eruption

Alejandra Reolid, Ester Muñoz‐Aceituno, Pedro Rodríguez‐Jiménez, D. de Argila

solar coexistente con urticaria crónica espontánea y erupción polimorfa lumínica Dear Editor:Solar urticaria (SU) is characterized by an immediate onset of erythema and itchy wheals within 5---10 min of exposure to solar radiation, which disappear in a few hours.1,2 Very uncommon isolated …

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Cutaneous vascular calcification. Perieccrine calcification as a diagnostic key for calciphylaxis

Alejandra Reolid, María Martínez‐Palazuelo, Pedro Rodríguez‐Jiménez, Ester Muñoz‐Aceituno et autres

BACKGROUND: Attempts have been made to establish discriminative criteria between classic calciphylaxis (CPX) and those cases in which cutaneous vascular calcification (CVC) represents an incidental finding (epiphenomenon). METHODS: Retrospective, observational cohort study of patients with CVC to distinguish clinicopathological features between CVC …

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Graft‐versus‐host disease‐associated angiomatosis with striking lipomatous metaplasia

Mar Llamas‐Velasco, Ester Muñoz‐Aceituno, Javier Sánchez Pérez, C. Camarero‐Mulas et autres

Sclerodermatous graft-versus-host disease (GvHD) is one of the many clinicopathological variants of chronic GvHD. One of the rarest forms of this variant is GvHD-associated angiomatosis (GvHD-AA). We describe the case of a 62-year-old male with sclerodermatous GvHD who presented, in consecutive years, …

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Epigenetics in Non-tumor Immune-Mediated Skin Diseases

Alejandra Reolid, Ester Muñoz‐Aceituno, Francisco Abad‐Santos, María C. Ovejero‐Benito et autres

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Study of Minimal Erythema Dose in a Series of Solar Urticaria

Pedro Rodríguez‐Jiménez, Pablo Chicharro, Alejandra Reolid, Ester Muñoz‐Aceituno et autres

Reduced minimal erythema dose (MED) is an abnormal erythematous reaction to light according to the skin phototype, which is determined by phototest. MED is reduced or abnormal in some photodermatoses. However, we have not found information about reduced MED in patients with …

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Talgdrüsenadenitis bei einem Mann mit autoimmunem Hintergrund

M. Herrero‐Moyano, Ester Muñoz‐Aceituno, María Teresa Fernández‐Figueras, Javier Fraga et autres

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DNA Copy Number Variation Associated with Anti-tumour Necrosis Factor Drug Response and Paradoxical Psoriasiform Reactions in Patients with Moderate-to-severe Psoriasis

Ancor Sanz‐García, Alejandra Reolid, L.H. Fisas, Ester Muñoz‐Aceituno et autres

Biological drugs targeting tumour necrosis factor are effective for psoriasis. However, 30-50% of patients do not respond to these drugs and may even develop paradoxical psoriasiform reactions. This study search-ed for DNA copy number variations that could predict anti-tumour necrotic factor drug …

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Pharmacogenetics Update on Biologic Therapy in Psoriasis

Ester Muñoz‐Aceituno, Luisa Martos‐Cabrera, María C. Ovejero‐Benito, Alejandra Reolid et autres

Background and objectives: Psoriasis is a chronic immune-mediated skin disease caused by several complex factors, both environmental and genetic, many of which are still not fully understood. Nowadays, several groups of biological drugs are being used for psoriasis treatment. Although these therapies …

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