Accès ouvert
2026
article
OpenAlex
Joseph K. Gaydos, Hendrik H. Nollens, Catherine F. Lo, M. Bradley Hanson et autres
To improve understanding of the health of Southern Resident killer whales (SRKWs; Orcinus orca) and contribute information to support recovery of this endangered population, a workshop was convened to discuss development of innovative methods for remotely assessing the health status of, and …
Accès ouvert
2023
erratum
OpenAlex
Ake T. Lu, Zhe Fei, Amin Haghani, Todd R. Robeck et autres
In the version of Supplementary Data initially published with this article, data were missing from Table S1.13 (Updated AnAge version in Class Mammalia), which now appear in an updated Supplementary Data file in the online version of the article.
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Accès ouvert
2023
article
OpenAlex
Ake T. Lu, Zhe Fei, Amin Haghani, Todd R. Robeck et autres
Aging, often considered a result of random cellular damage, can be accurately estimated using DNA methylation profiles, the foundation of pan-tissue epigenetic clocks. Here, we demonstrate the development of universal pan-mammalian clocks, using 11,754 methylation arrays from our Mammalian Methylation Consortium, which …
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Accès ouvert
2023
article
OpenAlex
Amin Haghani, Caesar Z. Li, Todd R. Robeck, Joshua Zhang et autres
Using DNA methylation profiles ( n = 15,456) from 348 mammalian species, we constructed phyloepigenetic trees that bear marked similarities to traditional phylogenetic ones. Using unsupervised clustering across all samples, we identified 55 distinct cytosine modules, of which 30 are related to …
us, sa, es, Tunisie, gb, au, Afrique du Sud, nz, ar, ca, fr, gl, pl, ch
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Accès ouvert
2021
article
OpenAlex
Todd R. Robeck, Zhe Fei, Ake T. Lu, Amin Haghani et autres
The development of a precise blood or skin tissue DNA Epigenetic Aging Clock for Odontocete (OEAC) would solve current age estimation inaccuracies for wild odontocetes. Therefore, we determined genome-wide DNA methylation profiles using a custom array (HorvathMammalMethyl40) across skin and blood samples …
us, es, ca
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Accès ouvert
2021
preprint
OpenAlex
Aimei Lu, Zhe Fei, Amin Haghani, Todd R. Robeck et autres
ABSTRACT Aging is often perceived as a degenerative process resulting from random accrual of cellular damage over time. Despite this, age can be accurately estimated by epigenetic clocks based on DNA methylation profiles from almost any tissue of the body. Since such …
us, nz, es, au, gb, ar, ca, fr, gl, pl
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2019
article
OpenAlex
Todd R. Robeck, Judy St. Leger, Heidi E. Robeck, Erika Nilson et autres
2018
article
OpenAlex
Keith A. Yip, Christopher Dold
Marine mammals are regularly moved between zoological parks, and transport of stranded, debilitated, wild marine mammals occurs during the work of rescue and rehabilitation. With careful attention to health, physiology, and welfare, and the use of technology appropriate to the type of …
2016
article
OpenAlex
Tatjana Sitt, Lizabeth Bowen, Chia-Shan Lee, Myra T. Blanchard et autres
us
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2014
other
OpenAlex
Christopher Dold, Sam H. Ridgway
Cetaceans (whales, dolphins, and porpoises) are mammals whose ancestors developed on land. Bottlenose dolphins, like all cetaceans, have an apneustic style of breathing. The physiology of anesthesia is different from sleep, especially in cetaceans. Specific anatomic and physiologic adaptations of the respiratory …
2014
book-chapter
OpenAlex
Christopher Dold
2014
paratext
OpenAlex
Mary K. Agnew, Roberto Aguilar, Jack L. Allen, Cheryl Asa et autres