V. Rohmer

Natural history of medullary thyroid carcinoma in MEN 2 patients carrying a variant at codon 804 in the RET proto-oncogene: A study by the French Neuroendocrine Tumor Group (GTE)

Valentine Suteau, Maylis Lebeault, Martin Jean Schlumberger, Mohamed Zalzali et autres

BACKGROUND: RET variants affecting codon 804 are part of the low-to-moderate risk group in the ATA classification, with indications for prophylactic thyroidectomy beyond age of 5years. However, aggressiveness seems to be variable. The objective of this study was to report a large …

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Prospective Multicentric Assessment of 68Ga-DOTANOC PET/CT in Grade 1-2 GEP-NET

Alexandre Lugat, Éric Frampas, Yann Touchefeu, Éric Mirallié et autres

The aim of this multicentric study was to prospectively compare 68Ga-DOTANOC PET/CT versus somatostatin receptor scintigraphy (SRS) with SPECT/CT, combined with multiphasic CT scan and MRI in patients with grade 1 or 2 gastroenteropancreatic neuroendocrine tumors (GEP-NET). Patients with histologically proven grade …

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Étude multicentrique prospective comparant la TEP/TDM au 68Ga-DOTANOC à l’imagerie conventionnelle optimisée dans le bilan lésionnel des tumeurs neuroendocrines gastro-entéro-pancréatiques de grade 1–2

Alexandre Lugat, Éric Frampas, Yann Touchefeu, Éric Mirallié et autres

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[Neuroendocrine neoplasms : a new era to the top of multidisciplinarity !]

L Lousberg, Joëlle Collignon, Florence Troisfontaine, A Paulus et autres

Neuroendocrine neoplasms are histologically defined by a common neuroendocrine cellular phenotype. These are still considered as rare tumours even though their incidence is increasing. Heterogeneity is everywhere whether in the localization of the primitive cancer, the clinical presentation, the histological classification, the …

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Anti-CEA Pretargeted Immuno-PET Shows Higher Sensitivity Than DOPA PET/CT in Detecting Relapsing Metastatic Medullary Thyroid Carcinoma: Post Hoc Analysis of the iPET-MTC Study

Caroline Bodet‐Milin, Alain Faivre-Chauvet, Thomas Carlier, Catherine Ansquer et autres

Pretargeting parameters for the use of anti–carcinoembryonic antigen (CEA) bispecific monoclonal antibody TF2 and the 68Ga-labeled IMP288 peptide for immuno-PET have been optimized in a first-in-humans study performed on medullary thyroid carcinoma (MTC) patients (the iPET-MTC study). The aim of this post …

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Multiple Endocrine Neoplasia-Type 2

V. Rohmer, Delphine Prunier‐Mirebeau, Iulia Potorac

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Pancreatic Neuroendocrine Neoplasm Associated with a Familial MAX Deletion

Sandrine Petignot, Adrian Daly, Emilie Castermans, Esther Korpershoek et autres

Abstract Most pancreatic neuroendocrine neoplasms (pNEN) occur sporadically but they can also occur as part of multiple endocrine neoplasia type 1 (MEN1). MAX was originally described as an inherited pheochromocytoma-paraganglioma risk gene, but also has recently been implicated in pituitary tumorigenesis. Here …

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MON-294 T2 MRI Signal Analysis of The Pituitary Gland Is Efficient in the Diagnosis of Acromegaly Due to GHRH Ectopic Secretion

Jean François Bonneville, Julia Potorac, V. Rohmer, Adrian Daly et autres

Abstract Less than 1% of cases of acromegaly are secondary to ectopic secretion of Growth Hormone Releasing Hormone (GHRH), usually from a neuroendocrine tumor. Symptoms of ectopic acromegaly did not differ from classical acromegaly from pituitary origin. GH and IGF 1 values …

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Les tumeurs neuroendocrines

V. Rohmer

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Multiple Endocrine Neoplasia-Type 2

V. Rohmer, Delphine Prunier‐Mirebeau, Iulia Potorac

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La gastrite chronique auto-immune : une prise en charge multidisciplinaire.

Hernan Gonzalo Valdes Socin, Philippe Leclercq, Marc Polus, V. Rohmer et autres

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Multiple Endocrine Neoplasia-Type 2

V. Rohmer, Delphine Prunier‐Mirebeau, Iulia Potorac

fr, be (code pays fourni par la source)