2025
conference-abstract
OpenAlex
Cienne Morton, Sophie Papa, Antonella A. Adami, Michael Metoudi et autres
Abstract Background: Advanced HNSCC has a dismal prognosis despite multiagent treatment. Epidermal growth factor receptor (EGFR, ErbB-1) is upregulated in most tumors, although EGFR-targeted therapy yields modest benefit. Other ErbB family members are commonly co-expressed, providing a rationale for targeting of the …
gb
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Julien Vionnet, Rosa Miquel, Juan G. Abraldeṣ, Juan José Lozano et autres
Background Long-term surviving liver transplant recipients can spontaneously develop operational tolerance, which allows them to completely discontinue their immunosuppression, but we lack validated tools to predict the likelihood of rejection following immunosuppression withdrawal. A previous clinical trial showed that a logistic regression …
gb, ca, es, be, de
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Julien Vionnet, Jorge P. Torres-Yaguana, Rosa Miquel, Juan G. Abraldeṣ et autres
The maintenance of stable allograft status in the absence of immunosuppression (IS), known as operational tolerance, can be achieved in a small proportion of liver transplant recipients, but we lack reliable tools to predict its spontaneous development. We conducted a prospective, multicenter, …
gb, ca, es, be, de, us
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Aleksander Hagen Erga, Anastasia Ushakova, Maria Elstad, Elise Constance Fodstad et autres
OBJECTIVE: This longitudinal cohort study aims to investigate the relationship between self-reported childhood maltreatment (CM) and the retrospective trajectory of substance use, mental health, and satisfaction with life in individuals with substance use disorders. METHODS: One hundred eleven treatment-seeking individuals with substance …
no, gb
(code pays fourni par la source)
Accès ouvert
2023
article
OpenAlex
Sophie Papa, Antonella A. Adami, Michael Metoudi, Richard Beatson et autres
Background Locally advanced/recurrent head and neck squamous cell carcinoma (HNSCC) is associated with significant morbidity and mortality. To target upregulated ErbB dimer expression in this cancer, we developed an autologous CD28-based chimeric antigen receptor T-cell (CAR-T) approach named T4 immunotherapy. Patient-derived T-cells …
gb
(code pays fourni par la source)
Accès ouvert
2023
article
OpenAlex
Maria Elstad, Saiam Ahmed, Jo Røislien, Abdel Douiri
OBJECTIVE: The objective of this systematic review was to examine how the record linkage process is reported in multimorbidity research. METHODS: A systematic search was conducted in Medline, Web of Science and Embase using predefined search terms, and inclusion and exclusion criteria. …
gb, pk, no
(code pays fourni par la source)
Accès ouvert
2022
review
OpenAlex
Maria Elstad, Abdel Douiri, Jo Røislien
ObjectivesThe objective for this systematic review was to examine how the record linkage process was reported and to understand challenges related to accessing, linking, and analysing linked routinely collected data used for multimorbidity research. ApproachA systematic search for relevant studies was conducted …
gb, no
(code pays fourni par la source)
Accès ouvert
2022
preprint
OpenAlex
Maria Elstad, Saiam Ahmed, Jo Røislien, Abdel Douiri
Abstract Background: Datasets from multi-sources that routinely collect healthcare information such as patient medical records, admissions and disease registries are increasingly used for medical research. In some cases, multiple sources are combined using data linkage techniques to create comprehensive datasets. The patient …
gb, pk, no
(code pays fourni par la source)
Accès ouvert
2022
article
OpenAlex
Matias Costa Vieira, Sophie Alexandra Relph, Walter Muruet-Gutierrez, Maria Elstad et autres
BACKGROUND: Antenatal detection and management of small for gestational age (SGA) is a strategy to reduce stillbirth. Large observational studies provide conflicting results on the effect of the Growth Assessment Protocol (GAP) in relation to detection of SGA and reduction of stillbirth; …
br, gb, au, nz
(code pays fourni par la source)
Accès ouvert
2021
article
OpenAlex
Julien Vionnet, Rosa Miquel, Juan G. Abraldeṣ, Jurate Wall et autres
BACKGROUND & AIMS: Management of long-term immunosuppression following liver transplantation (LT) remains empirical. Surveillance liver biopsies in combination with transcriptional profiling could overcome this challenge by identifying recipients with active alloimmune-mediated liver damage despite normal liver tests, but this approach lacks applicability. …
gb, ch, ca, es, be, de, us
(code pays fourni par la source)
Accès ouvert
2021
article
OpenAlex
Naomi Jane Wright, Andrew J M Leather, Niyi Ade‐Ajayi, Nick Sevdalis et autres
BACKGROUND: Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally. Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies have been done on these conditions in low-income and …
gb
(code pays fourni par la source)
Accès ouvert
2021
article
OpenAlex
Sophie Alexandra Relph, Maria Elstad, Bolaji Coker, Matias Costa Vieira et autres
BACKGROUND: The use of electronic patient records for assessing outcomes in clinical trials is a methodological strategy intended to drive faster and more cost-efficient acquisition of results. The aim of this manuscript was to outline the data collection and management considerations of …
gb, br, au
(code pays fourni par la source)