Activated PIK3CD drives innate B cell expansion yet limits B cell–intrinsic immune responses
Michelle N. Wray-Dutra, Fahd Al Qureshah, Genita Metzler, Mohamed Oukka et autres
52 citationsThe Journal of Experimental Medicine
Genita Metzler
Informations fournies par OpenAlex. Research Africa ne déduit ni nationalité, ni poste, ni coordonnées personnelles.
15Publications signalées
1715Citations signalées
1Affiliations récentes
Institutions déclarées
Domaines associés
T-cell and B-cell ImmunologyImmunotherapy and Immune ResponsesCAR-T cell therapy researchImmune Cell Function and InteractionDiabetes and associated disorders
Publications récentes
αv Integrins regulate germinal center B cell responses through noncanonical autophagy
Fiona Raso, Sara Sagadiev, Samuel W. Du, Emily Gage et autres
29 citationsJournal of Clinical Investigation
The Autoimmune Risk Variant PTPN22 C1858T Alters B Cell Tolerance at Discrete Checkpoints and Differentially Shapes the Naive Repertoire
Genita Metzler, Xuezhi Dai, Christopher D. Thouvenel, Socheath Khim et autres
24 citationsThe Journal of Immunology
Altered B cell signalling in autoimmunity
David J. Rawlings, Genita Metzler, Michelle N. Wray-Dutra, Shaun W. Jackson
306 citationsNature reviews. Immunology
An autoimmune risk variant in PTPN22 alters tolerance at multiple checkpoints during naive B cell development
Genita Metzler, Tony Dai, Chris Thouvenel, Jit Khim et autres
0 citationsThe Journal of Immunology
Cutting Edge: BAFF Promotes Autoantibody Production via TACI-Dependent Activation of Transitional B Cells
Holly M. Jacobs, Christopher D. Thouvenel, Sarah Leach, Tanvi Arkatkar et autres
51 citationsThe Journal of Immunology
BCR and co-receptor crosstalk facilitate the positive selection of self-reactive transitional B cells
Genita Metzler, Nikita Kolhatkar, David J. Rawlings
21 citationsCurrent Opinion in Immunology
The effect of an autoimmune-associated allelic variant of protein tyrosine phosphatase nonreceptor 22 on B cell tolerance in a murine model. (P4066)
Genita Metzler, David J. Rawlings
0 citationsThe Journal of Immunology
Ex Vivo Expansion of Human CD8+ T Cells Using Autologous CD4+ T Cell Help
Marcus O. Butler, Osamu Imataki, Yoshihiro Yamashita, Makito Tanaka et autres
42 citationsPLoS ONE
Establishment of Antitumor Memory in Humans Using in Vitro–Educated CD8 + T Cells
Marcus O. Butler, Philip Friedlander, Matthew I. Milstein, Mary M. Mooney et autres
105 citationsScience Translational Medicine
Human CD4+ T Cells Help CD8+ T Cells Proliferate Ex Vivo by Secreting Both IL-2/IL-21 and Upregulating IL-21R
Marcus O. Butler, Osamu Imataki, Yoshihiro Yamashita, Makito Tanaka et autres
0 citationsBlood
A Series of Human Cell-Based Artificial APC Expands Long-Lived, Th1-Biased, Viral Antigen-Specific CD4+ T Cells with a Central/Effector Memory Phenotpype Restricted by Common HLA-DR Alleles
Marcus O. Butler, Sascha Ansén, Makito Tanaka, Osamu Imataki et autres
0 citationsBlood
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