Santosh Man Shrestha

Adoption of Livestock Insurance among Dairy Farmers at Chitwan, Nepal

Sudip Poudel, Lalit BC, Santosh Man Shrestha, Sanjiv Subedi

Natural calamities, disease and pest, and unpredictable weather possess a high risk in livestock farming and cost a heavy loss to the farmers. Livestock insurance is one of the important strategies to reduce the risks related to livestock production. To assess the …

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Abstract 5697: Targeting CBL and CBLB ubiquitin ligases to exhaust cancer stem cells in metastatic breast cancer

Bhopal Mohapatra, Aaqib M. Bhat, Mohsin Raza, Haitao Luan et autres

Abstract Introduction: Recurrence, therapy resistance and metastasis remain major challenges in cancer therapy, accounting for nearly all deaths from cancer. The inability of current therapies to eliminate cancer stem cells (CSCs) is widely believed to underlie these challenges. Targeting molecular pathways that …

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Incidental left paraaortic mass in a patient with gall bladder adenocarcinoma: A diagnostic challenge

Sharma Paudel, Ongden Yonjen Tamang, Prajwal Dahal, Santosh Man Shrestha et autres

Incidental adrenal masses are frequently detected due to the extensive use of cross-sectional imaging, with about 3% to 7% of adults estimated to have them. Paragangliomas and pheochromocytomas (PPGL), rare tumors originating from paraganglia tissues, including the adrenal medulla, continue to be …

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Hematological and Biochemical Profiles of Patients with Dengue Virus Infection in Lalitpur, Nepal

Indira Rai, Subash Chandra Paudel, Santosh Man Shrestha, Debbie Manandhar

Dengue viral infection is a disease transmitted by mosquitoes of the Aedes genus, and it arises as a result of being bitten by mosquitoes that are carrying the virus. This infection induces a wide range of changes in the body’s immune system. …

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Liver Cirrhosis & Hepatocellular Carcinoma in Chronic Hepatitis B: Role of Hepatic Vena Cava Syndrome in the Pathogenesis

Santosh Man Shrestha

Background: Chronic hepatitis B (CHB) is highly prevalent in some Afro-Asian countries and is associated with high incidence of liver cirrhosis (LC) and hepatocellular carcinoma (HCC), whereas in the West with low prevalence it has a benign course.Pathogenesis of LC in CHB …

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W077 Correlation between thrombocytopenia and serum aminotransferases level in dengue fever patient

Santosh Man Shrestha

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Liver Cirrhosis in Chronic Hepatitis B: is it due to Hepatic Vena Cava Syndrome: case report

Santosh Man Shrestha

Chronic hepatitis B (CHB) is a common chronic viral infection of man. Hepatitis B Virus is not a cytopathic virus. Extensive intrahepatic viral replication is compatible with normally functioning hepatocytes. Patients with CHB in the West manifest as a ‘healthy carrier’, whereas …

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Splenomegaly and Hypersplenism in Hepatic Vena Cava Syndrome

Santosh Man Shrestha

Background and Aim: Hepatic vena cava syndrome (HVCS) is a bacterial infection-induced obliterative disease of the inferior vena cava at the site of the hepatic vein openings that causes chronic liver disease with a high incidence of liver cirrhosis and a moderate …

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Incidence of Inguinal Herniotomy in Children. A Prospective Study at a Regional Hospital

Devendra Shrestha, Narendra Vikram Gurung, Suresh Raj Poudel, Santosh Man Shrestha et autres

Background: Inguinal hernia is one of the most common surgical conditions in children. Herniotomy is the surgery performed for a pediatric hernia and hydrocele. This study was done to know the demography and outcome of pediatric herniotomy at our center. Materials and …

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Antibiotic Prophylaxis in Laparoscopic Cholecystectomy: A Retrospective Study

Santosh Man Shrestha, Binod Bade Shrestha, Pradip Ghimire

Introduction: Laparoscopic cholecystectomy is considered as the gold standard treatment for gallstone disease. There has remained a controversy on use of peri operative prophylactic antibiotics during laparoscopic cholecystectomy in reducing perioperative prophylaxis surgical site infections. Various studies has been done to evaluate …

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Incidental carcinoma of gallbladder following laparoscopic cholecystectomy: A single center study

Santosh Man Shrestha, Deepak Kumar Sharma, Roshan Ghimire, Dhiresh Kumar Maharjan et autres

Background: Gallbladder adenocarcinoma is the most common malignant tumor of the biliary tract. Most of gall bladder cancers are detected incidentally only after pathological examination of the excised surgical specimens. In this study we investigated the characteristics of incidental gallbladder cancers in …

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Blunt abdominal trauma leading to acute abdominal wall hernia: a case report

Dhruv Sharma, Santosh Man Shrestha, Roshan Ghimire

Acute traumatic abdominal wall hernia is a rare but serious diagnosis resulting from blunt abdominal trauma. The challenge of managing acute traumatic abdominal hernia is approach and timing of repair. We describe a 32 years male patient’s acute traumatic abdominal wall hernia …

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