Kazutaka Furukawa

Factors regulating tumor pressure in hepatocellular carcinoma and implications for tumor spread

T Tanaka, Naoki Yamanaka, Takeshi Oriyama, Kazutaka Furukawa et autres

This study was performed to investigate factors determining tumor pressure (TP) in hepatocellular carcinoma (HCC) and a correlation of pressure gradient between TP and portal vein pressure (PVP) with tumor spread. TP and hepatic tissue pressure (HTP) were measured in 70 patients …

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Hepatoprotective Effect of a Nonselective Endothelin Receptor Antagonist (TAK-044) in the Transplanted Liver

Naoki Yamanaka, Yutaka Takaya, Takeshi Oriyama, Kazutaka Furukawa et autres

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Topical cooling-assisted hepatic segmentectomy for cirrhotic liver with hepatocellular carcinoma.

Naoki Yamanaka, Kazutaka Furukawa, Takuji Tanaka, Wataru Tanaka et autres

BACKGROUND: A safe limit for normothermic consecutive portal triad occlusion in hepatectomy for the cirrhotic liver was believed to be around 30 minutes. Possibly, the occlusion time can be prolonged by cooling the ischemic liver in vivo. We describe the technique of …

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Microwave Coagulonecrotic Therapy for Hepatocellular Carcinoma

Naoki Yamanaka, Tsuneo Tanaka, Takeshi Oriyama, Kazutaka Furukawa et autres

The present study reports on the usefulness of microwave coagulonecrotic therapy (MCT) as a treatment option for hepatocellular carcinoma (HCC) with poor hepatic reserve. From June 1992 to March 1995, MCT using a microwave electrode was employed on 8 patients using laparoscopic …

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The role of microwave coagulation therapy for hepatocellular carcinoma

Tsuneo Tanaka, Naoki Yamanaka, Takeshi Oriyama, Kazutaka Furukawa et autres

Recent years, we experienced various treatment procedures for hepatocellular carcinoma (HCC), including hepatic resection, transcatheter hepatic artery embolization and percutaneous ethanol injection. However, Some patients could not receive these treatments because of the liver dysfunction and the location of the tumors. In …

A case of biloma which was developed from retention cyst in post hepatectomy patient by percutaneous microwave coagulation therapy for hepatocellular carcinoma : Report of a case

Masafumi Takata, Eizo Okamoto, Naoki Yamanaka, Takeshi Oriyama et autres

We report a case of biloma which was developed by communication between the biliary tract and the retention cyst in the post hepatectomy patient, following percutaneous microwave coagulation therapy (MCT) for hepatocellular carcinoma (HCC).The patient developed retention cyst after posterior segmentectomy of …

A report of resected mesenchymal hamartoma of the liver in adult.

Tatsuya Andoh, Eizou Okamoto, Naoki Yamanaka, Takeshi Oriyama et autres

我々は,検診にてCA19-9の軽度上昇を指摘され,超音波にて偶然発見された成人の肝間葉性過誤腫を経験したので報告する.症例は47歳の女性である.超音波やCTにて肝のS6より肝外性に発育する大きさ7cmの腫瘍を認め,腫瘍は充実性の部分と嚢胞性の部分にて構成されていた.血管造影では腫瘍全体に濃染像が見られた,良性腫瘍を最も疑ったが,悪性腫瘍も否定できず手術を施行した.切除標本では大きさ7.5cm×7.5cmの境界明瞭で光沢のある充実性腫瘍で,内部に大小の嚢胞を認めた.組織像では主に豊富な線維結合織よりなり,その間に大小の血管あるいはリンパ管や,小胆管の増生を認めた.現在,術後3年であるが,再発兆候はない.肝間葉性過誤腫の本邦報告例は64例であり,このうち15歳以下の小児例が52例と大部分を占め,成人例はわずか12例に過ぎない.小児例では腫瘍の発育速度は早く,成人例では発育速度は緩慢であるも悪性腫瘍との鑑別も困難で,共に切除が第一選択の治療である.悪性化や転移例はなく予後良好であるが,3例の再発例があり注意を要する.

Clinicopathologic spectrum of resected extraductal mass-forming intrahepatic cholangiocarcinoma

Naoki Yamanaka, Eizo Okamoto, Tatsuya Ando, Takeshi Oriyama et autres

BACKGROUND: The mode of tumor growth of intrahepatic cholangiocarcinoma (CC) varies considerably from patient to patient. This study describes the clinicopathologic variety of the extraductal mass-forming type of CC. METHODS: Patients with CC characterized by an extraductal mass (n = 26) who …

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Laparoscopic microwave coagulonecrotic therapy for hepatocellular carcinoma.

Naoki Yamanaka, Eizo Okamoto, T Tanaka, Takeshi Oriyama et autres

The present study reports on the usefulness of laparoscopic microwave coagulonecrotic therapy as a new option in the treatment of hepatocellular carcinoma. Five patients with liver tumors associated with cirrhosis were treated from July 1993 to March 1994 with a microwave electrode …

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[A case of giant bronchogenic cyst complicated with postoperative esophageal perforation].

Hiroyuki Fukushima, Makiko Hashimoto, Yukihiro Sato, Nobuo Oyama et autres

A 42-year-old man with giant bronchogenic cyst occupied from the middle and posterior mediastinum was treated surgically. The tumor was stoutly adhered to anterior aspect of the esophagus and membranous portion of the right bronchus. In dissecting the tumor, muscular coat of …

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Response of plasma and tissue endothelin-1 to liver ischemia and its implication in ischemia-reperfusion injury

Eisuke Kawamura, Naoki Yamanaka, Eizo Okamoto, Fumihito Tomoda et autres

This study was designed to investigate the changes in plasma and tissue endothelin-1/endothelin-2 (ET) after liver ischemia and to assess the protective effect of anti-ET 1/ET 2 monoclonal antibody (ET antibody) against ischemia-reperfusion injury. The ET levels in the liver tissue, hepatic …

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Hepatic resection under in situ hemihepatic hypothermic perfusion with hepatoprotective agents.

Naoki Yamanaka, Eizo Okamoto, Kazutaka Furukawa, T Oriyama et autres

Hepatectomy was performed under in situ right lobar hypothermic perfusion combined with hepatoprotective agents in six patients who had hepatocellular carcinoma and coexisting liver disease. Following occlusion of the right hepatic vein and the right portal pedicle, in situ cold perfusion was …

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