Accès ouvert
2026
article
OpenAlex
Manal Aljuhani, Azhaar Ashraf, Abdullah Alqarni, Mohammed S. Alshuhri et autres
Background: The role of cerebrospinal fluid (CSF) transforming growth factor β (TGF-β) isoforms in Alzheimer’s disease (AD) remains unclear. We examined associations of CSF TGF-β1, TGF-β2, and TGF-β3 with AD biomarkers, neurodegeneration, cognition, and clinical progression. Methods: In 294 ADNI participants with …
sa, gb
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
A Akhmimi, G H Y Lip, Tori Sprung, David Oxborough et autres
Resistant hypertension (RH) is associated with a high burden of cardiovascular morbidity and mortality. Early detection of subclinical myocardial dysfunction is essential for risk stratification and timely therapeutic intervention. Speckle tracking echocardiography (STE) is an advanced imaging technique that enables sensitive assessment …
gb, sa, dk
(code pays fourni par la source)
2025
article
OpenAlex
A Akhmimi, Victoria S. Sprung, G Y H Lip, David Oxborough et autres
Abstract Introduction Resistant hypertension (RH) has been associated with increased arterial stiffness, impaired endothelial function, and abnormalities in cardiac mechanics. However, the impact of intensified blood pressure (BP) management on improving arterial stiffness, endothelial function, and especially left ventricular (LV) and left …
gb
(code pays fourni par la source)
2025
article
OpenAlex
A Akhmimi, Victoria S. Sprung, Gregory Y.H. Lip, David Oxborough et autres
Abstract Introduction Patients with resistant hypertension (RH) suffer from a high rate of cardiovascular (CV) complications and have poor prognosis. Given the poor prognosis in RH patients, early identification of subclinical myocardial abnormalities is of clinical importance to allow for timely preventive …
gb
(code pays fourni par la source)
Accès ouvert
2023
article
OpenAlex
A Akhmimi, Victoria S. Sprung, G Y H Lip, David Oxborough et autres
Abstract Introduction People living with resistant hypertension (RH) have a higher prevalence of target organ damage, and demonstrate increased risk of cardiovascular (CV) morbidity and mortality. There are distinctive vascular structural and functional changes associated with hypertension. Among these, endothelial dysfunction and …
gb
(code pays fourni par la source)
Accès ouvert
2020
editorial
OpenAlex
A Akhmimi, Gregory Y.H. Lip, Alena Shantsila
Hypertension is considered one of the most significant causes of global morbidity and mortality regardless of the treatment progressions through the past decades [1,2]. In 2017 and 2018, recent gui...
gb, sa, dk
(code pays fourni par la source)