Accès ouvert
2025
article
OpenAlex
Shrushti Shah, Chunlong Mu, Grace Shen‐Tu, Kristina Schlicht et autres
The mechanisms linking gut microbiota to hypertension remain unclear. This study shows that hypertension is linked to shifts in the abundance of functionally relevant gut microbial taxa in middle-aged women. Changes were characterized by expansion of proinflammatory bacteria, systemic inflammation, and altered …
ca, us, de, at
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Shrushti Shah, Chunlong Mu, Grace Shen‐Tu, Nathalie Rohmann et autres
BACKGROUND: A plant-focused, healthy dietary pattern, such as the Mediterranean diet enriched with dietary fiber, polyphenols, and polyunsaturated fats, is well known to positively influence the gut microbiota. Conversely, a processed diet high in saturated fats and sugars negatively impacts gut diversity, …
ca, de
(code pays fourni par la source)
Accès ouvert
2025
preprint
OpenAlex
Shrushti Shah, Chunlong Mu, Grace Shen‐Tu, Kristina Schlicht et autres
ABSTRACT Background Hypertension affects over 1.28 billion adults worldwide, including a significant number of women. Although the gut microbiome is implicated in the onset and progression of hypertension, few studies have examined the relationship in middle-aged women. Methods Within an established cohort, …
ca, de, at
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Jane Shearer, Shrushti Shah, Martin J. MacInnis, Grace Shen‐Tu et autres
Oral iron supplementation is the first-line treatment for addressing iron deficiency, a concern particularly relevant to women who are susceptible to sub-optimal iron levels. Nevertheless, the impact of iron supplementation on the gut microbiota of middle-aged women remains unclear. To investigate the …
ca
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Jane Shearer, Shrushti Shah, Grace Shen‐Tu, Kristina Schlicht et autres
Human gut microbiota are recognized as critical players in both metabolic disease and drug metabolism. However, medication–microbiota interactions in cardiometabolic diseases are not well understood. To gain a comprehensive understanding of how medication intake impacts the gut microbiota, we investigated the association …
ca, us, au, de
(code pays fourni par la source)
Accès ouvert
2023
article
OpenAlex
Shrushti Shah, Chunlong Mu, Shirin Moossavi, Grace Shen‐Tu et autres
Abstract Physical inactivity is one of the leading causes of chronic metabolic disease including obesity. Increasing physical activity (PA) has been shown to improve cardiometabolic and musculoskeletal health and to be associated with a distinct gut microbiota composition in trained athletes. However, …
ca, de, at
(code pays fourni par la source)
2022
article
OpenAlex
Alexander Thomas Cohen, Virginia Noxon, Amol D. Dhamane, Shrushti Shah et autres
Introduction: Cancer patients with kidney disease are at increased risk for having venous thromboembolism (VTE) and bleeding than those without kidney disease. There is a lack of evidence about the effectiveness and safety of anticoagulants in cancer patients with VTE and kidney …
gb, us, es
(code pays fourni par la source)
Accès ouvert
2022
article
OpenAlex
Tiffany A. Fillier, Shrushti Shah, Karen M. Doody, Thu Huong Pham et autres
Communication between gut microbiota and the brain is an enigma. Alterations in the gut microbial community affects enteric metabolite levels, such as short chain fatty acids (SCFAs). SCFAs have been proposed as a possible mechanism through which the gut microbiome modulate brain …
ca
(code pays fourni par la source)
2022
article
OpenAlex
Lea Henneke, Kristina Schlicht, Nadia Andrea Andreani, Tim Hollstein et autres
Recent rodent microbiome experiments suggest that besides Akkermansia, Parasutterella sp. are important in type 2 diabetes and obesity development. In the present translational human study, we aimed to characterize Parasutterella in our European cross-sectional FoCus cohort (n=1.544) followed by validation of the …
de, ca
(code pays fourni par la source)
Accès ouvert
2022
article
OpenAlex
Lea Henneke, Kristina Schlicht, Nadia Andrea Andreani, Tim Hollstein et autres
Recent rodent microbiome experiments suggest that besides Akkermansia, Parasutterella sp. are important in type 2 diabetes and obesity development. In the present translational human study, we aimed to characterize Parasutterella in our European cross-sectional FoCus cohort (n = 1,544) followed by validation …
de, ca
(code pays fourni par la source)
Accès ouvert
2022
dissertation
OpenAlex
Shrushti Shah
Short chain fatty acids (SCFAs), generated from the microbial fermentation of dietary fibers, alter lipid metabolism. However, sex-specific effects of SCFAs on lipid metabolism and lipidomic profiles are not known. Male and female Long-Evans rats were either given a mixture of SCFAs …
ca
(code pays fourni par la source)
Accès ouvert
2021
preprint
OpenAlex
Tiffany A. Fillier, Shrushti Shah, Karen M. Doody, Thu Huong Pham et autres
Abstract Communication between gut microbiota and the brain is an enigma. Alterations in the gut microbial community affects enteric metabolite levels, such as SCFAs. SCFAs have been proposed as a possible mechanism through which the gut microbiome modulate brain health and function. …
ca
(code pays fourni par la source)