Jieming Zhang

Clinical and zebrafish studies of truncating SF3B2-variants in craniofacial microsomia

Dan Xia, Xiaofang Peng, Zihao Deng, Shuyun Deng et autres

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Sexually dimorphic expression and hormonal responsiveness of steroidogenic Cyp genes during gonadal differentiation in mandarin fish

Jieming Zhang, Shengyue Lin, Ziyan Deng, Weijian Chen et autres

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Integrated Network Toxicology and Multi-Omics Reveal Budesonide-Induced Immunotoxicity Mechanisms in Zebrafish Embryos

Shenao Liu, Zixuan He, Jieming Zhang, Haiying Yang et autres

Formation mechanism of transfer films between PEEK-based materials and silicon nitride ceramic balls under varying loads

Jian Wei Sun, Yang Zhang, Kun Wang, Zhi-Li Zhang et autres

Purpose This study aims to further investigate the tribological behavior of polyether ether ketone (PEEK) and its composites against silicon nitride (Si3N4), with a focus on analyzing the transfer film formation mechanism and the lubricating roles of various fillers in the PEEK …

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Real-world analysis of axicabtagene ciloleucel (axi-cel) as consolidation therapy following first-line treatment in B-cell lymphoma with high-risk factors

Jieming Zhang, Mengjie Ding, Feifei Nan, Xiaorui Fu et autres

Abstract Background: Approximately 60% of patients with large B-cell lymphoma (LBCL) achieve cure with standard first-line (1L) therapies, such as R-CHOP or DA-EPOCH-R. However, 10% of patients remain refractory to 1L treatment, and 30% of responders experienced relapse within two years. Axicabtagene …

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Deoxycorticosterone acetate–induced acceleration of embryogenesis and oxidative and metabolic stresses in zebrafish

Kaifeng Wang, Jieming Zhang, Chong Han, Qiang Li et autres

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Construction of multiple heterointerfaces in layered thermoelectric nanocoating to realize highly sensitive remote fire-warning

Huali Xie, Jieming Zhang, Xuejun Lai, Kunquan Li et autres

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Novel ANKRD17 variants implicate synaptic and mitochondrial disruptions in intellectual disability and autism spectrum disorder

Dan Xia, Yuanyuan Xu, Zhanwen He, Rui Chen et autres

ANKRD17 has recently been implicated in intellectual disability (ID) and autism spectrum disorder (ASD); however, the underlying molecular mechanisms remain unclear. Using trio whole-exome sequencing (Trio-WES) and chromosomal microarray analysis (CMA), we identified two unrelated cases with novel de novo heterozygous ANKRD17 …

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Tumor-Specific Activatable Nanopaltform Achieves Oxidative Stress Amplification and Reversal of Cisplatin Resistance to Provoke Enhanced Ferroptosis–Apoptosis Cancer Therapy

Jieming Zhang, Fangfang Zhou, Xin Du, Meiru Zhang et autres

Cisplatin-based chemotherapy is widely used to combat cancers through an apoptosis pathway. However, drug resistance induced by upregulated glutathione (GSH) in tumor cells and systemic side effects significantly compromise its therapeutic efficacy. The application of nanocarriers with a GSH-scavenging ability is a …

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Construction of Multiple Heterointerfaces in Layered Thermoelectric Nanocoating to Realize Highly Sensitive Remote Fire-Warning

Huali Xie, Jieming Zhang, Xuejun Lai, Kunquan Li et autres

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POD 12 As a Robust Prognostic Index in Patients with Angioimmunoblastic T-Cell Lymphoma: A Single-Center Study

Suxiao Li, Xiaoyan Feng, Jieming Zhang, Yunfei Song et autres

Objective:To analyze a set of prognostic factors for angioimmunoblastic T-cell lymphoma (AITL) and determine whether early progression of disease (POD) is associated with poor prognosis in patients with AITL. Methods: In this study, we enrolled 231 AITL patients from the First Affiliated …

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Strikingly Reduced Toxicities of Fotemustine-Based Chemotherapeutics Than High-Dose Methotrexate-Containing Regimens with Comparable Efficacy

Xudong Zhang, Mengke Fan, Wenhua Wang, Jingjing Wu et autres

Background: High-dose methotrexate (HD-MTX)-based chemotherapy followed by whole-brain radiotherapy is the most commonly used approach for patients with newly diagnosed Primary central nervous system lymphoma (PCNSL). However, HD-MTX is a hospital-based drug requiring adequate fluid management and may not be well tolerated …

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