J. Diedrich

Rare HCV subtypes and retreatment outcomes in a cohort of European DAA-experienced patients

Julia Dietz, Christiana Graf, Christoph P. Berg, Kerstin Port et autres

Background and Aims: Data on the prevalence and characteristics of so-called rare HCV genotypes (GTs) in larger cohorts is limited. This study investigates the frequency of rare GT and resistance-associated substitutions and the efficacy of retreatment in a European cohort. Methods: A …

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Long-term persistence of HCV resistance-associated substitutions after DAA treatment failure

Julia Dietz, Beat Müllhaupt, Peter Buggisch, Christiana Graf et autres

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Efficacy of Retreatment After Failed Direct-acting Antiviral Therapy in Patients With HCV Genotype 1–3 Infections

Julia Dietz, Ulrich Spengler, Beat Müllhaupt, Julian Schulze zur Wiesch et autres

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M2 macrophages derived from patients with idiopathic pulmonary arterial hypertension are susceptible for apelin-mediated suppression of pro-inflammatory cytokines

Lars Harbaum, Jasmin Wellbrock, J. Diedrich, Jan K. Hennigs et autres

Background: Apelin (APLN) and its receptor (APLN-R) have been indicated to influence inflammatory processes. The present analysis aimed (1) to demonstrate the possible involvement of alternatively activated (M2) macrophages to the pathogenesis of idiopathic pulmonary arterial hypertension (IPAH) and (2) to assess …

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