Biochemical diagnosis of pheochromocytoma and paraganglioma: analytical challenges and perspectives for optimization
François Fraissinet, Théophile Charpentier, Hélène Girot, Brunel et autres
Pheochromocytomas and paragangliomas (PPGL) are rare but potentially life-threatening neuroendocrine tumors whose diagnosis relies primarily on the biochemical detection of excessive catecholamine production or metabolism. Plasma free metanephrines and urinary fractionated metanephrines remain the cornerstone biomarkers recommended for initial screening. However, their …
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