Chitrakshi Pant

Identification of 2,4-dihydroxy-azaflavanone as an allosteric activator of SIRT1 and its potential role in cellular models of Parkinson’s disease

Chitrakshi Pant, Vidya Jyothi Alli, Genji Sukumar, Abhijit Mohapatra et autres

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Allosteric Activation of SIRT1 by 2,4-Dihydroxy-azaflavanone Averts MPP+-Mediated Dysfunction in Mitochondrial Biogenesis and Bioenergetics: Implications for Parkinson’s Disease

Chitrakshi Pant, Genji Sukumar, Vidya Jyothi Alli, Surender Singh Jadav et autres

Parkinson’s disease (PD) is a complex neurodegenerative disorder that affects dopamine neurons of the substantia nigra pars compacta (SNpc), resulting in motor dysfunction. Among the pathways examined, mitochondria and α-synuclein were found to play a major role in the disease progression. Hence, …

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Rv0547c, a functional oxidoreductase, supports Mycobacterium tuberculosis persistence by reprogramming host mitochondrial fatty acid metabolism

Jayashankar Medikonda, Nandini Wankar, Suman Asalla, Sufi Oasim Raja et autres

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Aza-Flavanone Diminishes Parkinsonism in the Drosophila melanogaster Parkin Mutant

Chitrakshi Pant, Moumita Chakrabarti, Jolly Janette Mendonza, Bogonda Ganganna et autres

Parkinson’s disease is a chronic and progressive neurodegenerative disease, induced by slow and progressive death of the dopaminergic (DA) neurons from the midbrain region called substantia nigra (SNc) leading to difficulty in locomotion. At present, very few potential therapeutic drugs are available …

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Inhibitory role of oleanolic acid and esculetin in HeLa cells involve multiple signaling pathways

Prajitha Mohandas Edathara, Shivakanth Chintalapally, Venkata Krishna Kanth Makani, Chitrakshi Pant et autres

in (code pays fourni par la source)