Léa Rey

Neuro-immunological regulation of intestinal physiology by enkephalins

Léa Rey

De nombreuses études ont montré le rôle des opioïdes d'origine immunitaire dans la régulation des processus inflammatoires et de la douleur. Lors d'une inflammation intestinale, les douleurs abdominales induites par l'activation des afférences nociceptives sont atténuées par les opioïdes libérés par les …

Toxoplasma gondii chronic infection decreases visceral nociception through peripheral opioid receptor signaling

Alexis Audibert, Xavier Mas‐Orea, Léa Rey, Marcy Belloy et autres

By eliciting immune activation in the digestive tract, intestinal pathogens may perturb gut homeostasis. Some gastrointestinal infections can indeed increase the risk of developing post-infectious irritable bowel syndrome (PI-IBS). Intriguingly, the prevalent foodborne parasite Toxoplasma gondii has not been linked to the …

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Toxoplasma gondii chronic infection decreases visceral nociception through peripheral opioid receptor signaling

Alexis Audibert, Xavier Mas‐Orea, Léa Rey, Marcy Belloy et autres

Abstract By eliciting immune activation in the digestive tract, intestinal pathogens may perturb gut homeostasis. Some gastrointestinal infections can indeed increase the risk of developing post-infectious irritable bowel syndrome (PI-IBS). Intriguingly, the prevalent foodborne parasite Toxoplasma gondii has not been linked to …

fr (code pays fourni par la source)

Proenkephalin deletion in hematopoietic cells induces intestinal barrier failure resulting in clinical feature similarities with irritable bowel syndrome in mice

Xavier Mas‐Orea, Léa Rey, Louise Battut, Cyrielle Bories et autres

Opioid-dependent immune-mediated analgesic effects have been broadly reported upon inflammation. In preclinical mouse models of intestinal inflammatory diseases, the local release of enkephalins (endogenous opioids) by colitogenic T lymphocytes alleviate inflammation-induced pain by down-modulating gut-innervating nociceptor activation in periphery. In this study, …

fr (code pays fourni par la source)

Social support from health care providers is associated with reduced illness intrusiveness in hemodialysis patients

Luca Neri, Diego Brancaccio, Léa Rey, F. Rossa et autres

BACKGROUND: End-stage renal disease (ESRD) disrupts patients' life styles, interests and activities negatively affecting their quality of life. Social support has been previously associated with favorable health outcomes. However, no study has examined the association of social support from health care providers …

it (code pays fourni par la source)

Thymomas in Myasthenia gravis (MG)

Guillermo Menga, M Rosenberg, G Olmedo, Claudia Poleri et autres