Chikato Koga

Idiopathic esophageal intramural hematoma associated with hemothorax leading to esophageal perforation

Atsushi Gakuhara, Ryugo Teranishi, Kurumi Tsuchihashi, Soichiro Minami et autres

Idiopathic intramural hematoma of the esophagus is a rare condition associated with Mallory–Weiss syndrome or spontaneous esophageal rupture. It is usually manageable with conservative treatment but, in rare cases, may be complicated by hemothorax or progress to esophageal perforation. We report the …

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Study protocol: A randomized controlled trial of chemoradiotherapy versus chemotherapy as neoadjuvant therapy for resectable pancreatic cancer (CSGO-HBP-027)

Yoshito Tomimaru, Hirofumi Akita, Keisuke Tamari, Sakae Maeda et autres

Despite advances in multimodal treatment, the long-term survival of patients with resectable pancreatic ductal adenocarcinoma (PDAC) remains poor. In Japan, neoadjuvant chemotherapy with gemcitabine and S-1 (GS) has demonstrated a survival benefit compared with upfront surgery. The addition of radiotherapy to chemotherapy …

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Laparoscopic Local Resection via Duodenotomy for Cystic Heterotopic Pancreas Involving the Gastroduodenal Junction: A Case Report

Atsushi Gakuhara, Ryugo Teranishi, Yosuke Yamahira, Nozomi Mikami et autres

INTRODUCTION: Heterotopic pancreas is an uncommon condition characterized by the pancreatic tissue lacking anatomical continuity with the main pancreas. Cystic changes are rare, and lesions involving the gastroduodenal junction present diagnostic and technical challenges because the exact site of origin may be …

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[A Case of Pancreatic Acinar Cell Carcinoma Undergoing Two Hepatic Resections for Metachronous Liver Metastases].

Shoko Minamiura, Masanori Tsujie, Daisuke Takiuchi, Chikato Koga et autres

The patient was a woman in her 60s who was referred to our hospital for further evaluation and treatment of a pancreatic body mass. Endoscopic ultrasound-guided fine-needle aspiration(EUS-FNA)suggested a diagnosis of solid pseudopapillary neoplasm, and she subsequently underwent a spleen-preserving distal pancreatectomy. …

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Pancreatic Fat Accumulation Impacts Postoperative Survival in Patients With Pancreatic Ductal Adenocarcinoma

Y Fukuda, Chikato Koga, Soichiro Minami, Satoshi ISHIKAWA et autres

BACKGROUND: Pancreatic fat accumulation, that is, fatty pancreas (FP), has gained attention because it contributes to pancreatic carcinogenesis. However, the impact of FP on the survival of patients with pancreatic cancer has not yet been elucidated. METHODS: Overall, 87 consecutive patients who …

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Nutritional management during chemotherapy and chemoradiotherapy for advanced esophageal cancer

Yutaka Kimura, Atsushi Gakuhara, Shuichi Fukuda, Yasunari Fukuda et autres

Advanced esophageal cancer is treated by chemotherapy, radiation therapy, chemoradiotherapy, and immunotherapy. However, the stenosis caused by the tumor and cancer-related chronic inflammation leads to inadequate food intake, weight loss, and nutrition problems. Given that poor pre-treatment nutritional status increases the risks …

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Spontaneously Ruptured Pancreatic Mucinous Cystic Neoplasm: A Case Report

Masataka Hirano, Masanori Tsujie, Takayoshi Goto, Chikato Koga et autres

INTRODUCTION: Pancreatic mucinous cystic neoplasm (MCN) is a cystic tumor of the pancreas typically located in the pancreatic body or tail in middle-aged women. However, MCN rupture is rare. This report describes a case of MCN with spontaneous rupture during follow-up. CASE …

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Endometrioid adenocarcinoma arising from inguinal endometriosis during follow-up for gastric cancer surgery: a case report and literature review

Atsushi Gakuhara, Shuichi Fukuda, Terukazu Yoshihara, Yasunari Fukuda et autres

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313. EXPERIENCE OF 4 CASES TREATED WITH IPI + NIVO FOR RECURRENT ADVANCED ESOPHAGEAL CANCER

Hiromichi Miyagaki, Yukihiro Yoshikawa, Souichiro Mori, Masatoshi Nomura et autres

Abstract Background The results of the Checkmate 648 trial have made nivolumab plus ipilimumab available in general practice as first-line treatment for advanced recurrent esophageal squamous cell carcinoma. Unlike regimens that include chemotherapy, this regimen can be used in patients with renal …

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Single-incision laparoscopic surgery for intestinal intussusception due to neuroendocrine tumor

Toshinori Sueda, Mitsuyoshi Tei, Soichiro Mori, Kentaro Nishida et autres

BACKGROUND: Small intestinal neuroendocrine tumor (NET) is uncommon, but intestinal intussusception caused by NET is even rare. We report a rare case of single-incision laparoscopic surgery (SILS) for intestinal intussusception due to NET G1. CASE PRESENTATION: A 72-year-old woman presented with vomiting, …

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[A Case of Advanced Gastric Cancer in Which Tumor Relapse Was Observed after Discontinuation of Nivolumab Due to Complete Response, and for Which Re-Administration Was Initiated].

Kentaro Nishida, Hisashi Yagi, RIE MIZUMOTO, Masahiro Haeno et autres

A 61-year-old male was diagnosed with unresectable advanced gastric cancer(cT4b[SI; panc], N+, M0, cStage ⅣA). However he was administered S-1 plus oxaliplatin as a primary treatment and ramucirumab plus paclitaxel as a secondary treatment, the primary tumor and lymph nodes were enlarged. …

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Clinical Impact of Transanal Drainage Tube on Anastomosis Leakage following Minimally Invasive Anterior Resection without Diverting Stoma in Patients with Rectal Cancer: A Propensity Score-Matched Analysis

Toshinori Sueda, Mitsuyoshi Tei, Soichiro Mori, Kenataro Nishida et autres

Abstract Purpose As one of the most serious complications of rectal cancer (RC) surgery, preventing anastomotic leakage (AL) is crucial. Several studies have suggested a positive role of the transanal drainage tube (TaDT) in AL prevention. However, whether TaDT is beneficial for …

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