Junnosuke Hayasaka

Incidence of Metachronous Gastric Cancer After Endoscopic Submucosal Dissection in Helicobacter pylori-uninfected Early Gastric Cancer

Yusuke Kawai, Junnosuke Hayasaka, Yorinari Ochiai, Junji Tanaka et autres

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Central Depression among Pretreatment Endoscopic Features is Associated with Submucosal Invasion in Gastric Fundic Gland-Type Tumors

Junnosuke Hayasaka, Yorinari Ochiai, Yusuke Kawai, Yutaka Takazawa et autres

Introduction: Fundic gland-type neoplasms show a relatively high frequency of submucosal (SM) invasion despite their small size and low-grade biological behavior. Reliable pretreatment endoscopic predictors of SM invasion, however, remain limited. This study aimed to evaluate the association between pretreatment endoscopic features …

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Distinct clinical course and poor outcomes of small bowel bleeding in acute hematochezia: a nationwide multicenter study

Yuga Komaki, Naoyuki Tominaga, Atsuo Yamada, Eiji Sadashima et autres

Although small bowel bleeding is a known cause of acute lower gastrointestinal bleeding (ALGIB), its outcomes compared to colorectal bleeding remain underexplored. This study aimed to identify baseline characteristics and short- and long-term outcomes associated with small bowel bleeding in comparison to …

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Two-needle-holder endoscopic hand suturing for a mucosal defect after rectal endoscopic submucosal dissection

Junnosuke Hayasaka, Yusuke Kawai, Hitomi Iwasaki, Yorinari Ochiai et autres

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Evaluating the Frequency of Esophageal Motility Disorders in Patients With Upper Gastrointestinal Symptoms Based on the Chicago Classification Version 3.0

Yorinari Ochiai, Yasutaka Kuribayashi, Akihiro Yamada, Hiroyuki Odagiri et autres

INTRODUCTION: Patients with upper gastrointestinal (GI) symptoms may have esophageal motility disorders (EMDs). Esophageal high-resolution manometry (HRM) is often performed when no obvious abnormalities are observed on esophagogastroduodenoscopy (EGD). However, few reports from Japan have evaluated the relationship between symptoms and EMDs …

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Factors Influencing Resection Time in Endoscopic Submucosal Dissection for Rectal Neuroendocrine Tumors

Shinya Nakatani, Junnosuke Hayasaka, Tsuyoshi Ishii, Minoru Oda et autres

ABSTRACT Objectives The usefulness of endoscopic submucosal dissection (ESD) for rectal neuroendocrine tumors (NETs) is well established. However, factors influencing resection time remain unclear. This study aimed to identify these factors during ESD for rectal NETs. Methods This retrospective study included 194 …

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Effectiveness of Potassium-Competitive Acid Blockers and Proton Pump Inhibitors on Esophageal Wall Thickening in Eosinophilic Esophagitis

Yugo Suzuki, Kei Kono, Yorinari Ochiai, Junnosuke Hayasaka et autres

Background/Aims: The efficacy of proton pump inhibitors (PPIs) and potassium-competitive acid blockers (P-CABs) in the treatment of eosinophilic esophagitis (EoE) has been well established. This study aimed to clarify the impact of PPIs/P-CABs on esophageal wall thickness and clinical symptoms in EoE …

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Cold Forceps Polypectomy with Jumbo Forceps for Foveolar-type Gastric Adenoma with a Raspberry-like Appearance in an Outpatient Setting

Junnosuke Hayasaka, Daisuke Kikuchi, Yutaka Takazawa, Shu Hoteya

The optimal endoscopic treatment for foveolar-type gastric tumors with raspberry-like appearance remains unclear. A 51-year-old man underwent endoscopic treatment for a 4-mm foveolar-type gastric tumor with a raspberry-like appearance. Because the patient preferred outpatient treatment, resection was performed using cold forceps polypectomy …

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Impact of Therapeutic Agents on Serum Leucine-Rich Alpha-2 Glycoprotein for Monitoring Endoscopically Remitted Ulcerative Colitis

Junnosuke Hayasaka, Akira Matsui, Daisuke Kikuchi, Shu Hoteya

INTRODUCTION: Serum leucine-rich alpha-2 glycoprotein (LRG) levels are measured to monitor ulcerative colitis; however, the impact of concomitant medications on LRG remains unclear. This exploratory study aimed to determine the effects of various agents on serum LRG levels. METHODS: We conducted a …

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Vonoprazan vs. Esomeprazole: Scarring Rate of Post-endoscopic Submucosal Dissection Ulcers in the Postoperative Stomach

Kosuke Nomura, Yugo Suzuki, Yorinari Ochiai, Junnosuke Hayasaka et autres

(p<0.05), and the postoperative bleeding rates were 5.4% and 7.7%, respectively. There were no significant differences in sex, surgical procedure, diabetes status, or use of steroids, nonsteroidal anti-inflammatory drugs, or antithrombotic medications. An analysis using propensity scores to adjust for age, sex, …

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AFP-producing adenocarcinoma arising from ectopic gastric mucosa in the cervical esophagus treated with endoscopic submucosal dissection

Yugo Suzuki, T Ishi, Yusuke Kawai, Minoru Oda et autres

An 87-year-old man with dysphagia was diagnosed with esophageal adenocarcinoma. Endoscopic examination revealed a 15-mm, erythematous elevated lesion in the cervical esophagus continuous with the ectopic gastric mucosa. Neither computed tomography nor 2-fluoro-2-deoxy-D-glucose-positron emission tomography revealed signs of lymph node or distant …

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Step-Down Therapy Using Vonoprazan for Giant Gastric Polyps in Long-Term Proton Pump Inhibitor Administration

Daisuke Kikuchi, Yorinari Ochiai, Yoshio Hoshihara, Yugo Suzuki et autres

Introduction: Gastroesophageal reflux disease (GERD) is diagnosed based on bothersome symptoms, such as heartburn, and the presence of mucosal breaks endoscopically. Treatments that suppress gastric acid, such as proton pump inhibitor (PPI) and vonoprazan, are frequently administered. Several studies reported regarding the …

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