Accès ouvert
2023
article
OpenAlex
Florian Juszczak, Louise Pierre, Morgane Decarnoncle, Inès Jadot et autres
BACKGROUND: Sex differences have been observed in the development of obesity-related complications in patients, as well as in animal models. Accumulating evidence suggests that sex-dependent regulation of lipid metabolism contributes to sex-specific physiopathology. Lipid accumulation in the renal tissue has been shown …
be
(code pays fourni par la source)
2023
article
OpenAlex
Francesca Grieco, Stephanie P. Vo, Olivia Botton, Y. Dimitri et autres
Accès ouvert
2022
article
OpenAlex
Thomas Baudoux, Inès Jadot, Anne‐Émilie Declèves, Marie‐Hélène Antoine et autres
Aristolochic acid nephropathy (AAN) is a progressive tubulointerstitial nephritis caused by the intake of aristolochic acids (AA) contained in Chinese herbal remedies or contaminated food. AAN is characterized by tubular atrophy and interstitial fibrosis, characterizing advanced kidney disease. It is established that …
be
(code pays fourni par la source)
Accès ouvert
2020
article
OpenAlex
Florian Juszczak, Maud Vlassembrouck, Olivia Botton, Thomas Zwakhals et autres
Exercise training is now recognized as an interesting therapeutic strategy in managing obesity and its related disorders. However, there is still a lack of knowledge about its impact on obesity-induced chronic kidney disease (CKD). Here, we investigated the effects of a delayed …
be
(code pays fourni par la source)
2019
conference-abstract
OpenAlex
Pauline Mosseray, Inès Jadot, Louise Pierre, Florian Juszczak et autres
fr, be
(code pays fourni par la source)
2019
conference-paper
OpenAlex
Florian Juszczak, Maud Vlassembrouck, Thomas Zwakhals, Vincianne Jenart et autres
Background: The increased incidence of obesity in Western countries is largely due to a combination of sedentary lifestyle, associated with a high caloric intake and a lack of exercise. Furthermore, systematic reviews and meta-analysis demonstrated that obesity serves as an independent predictor …
2018
conference-paper
OpenAlex
Inès Jadot, Florian Juszczak, Olivia Botton, Joëlle Nortier et autres
BODY-Background: Even though impaired kidney function is classified into two distinct categories, the acute (AKI) and the chronic (CKD) kidney disease, recent epidemiologic and mechanistic studies demonstrated that AKI and CKD are interconnected. Indeed, AKI is a risk factor for the development …
2018
conference-paper
OpenAlex
Florian Juszczak, Inès Jadot, Julie Storder, Olivia Botton et autres
BODY-Background: Obesity and metabolic syndrome are independent risk factors for chronic kidney disease (CKD). Obesity-induced CKD is characterized by a progressive decline of the renal function and the development of tubulointerstitial fibrosis. Recently, studies showing ectopic lipid depositions in proximal tubular cells …
fr
(code pays fourni par la source)
Accès ouvert
2017
article
OpenAlex
Inès Jadot, Vanessa Colombaro, Blanche Martin, Isabelle Habsch et autres
Aristolochic Acid (AA) nephropathy (AAN) is a progressive tubulointerstitial nephritis characterized by an early phase of acute kidney injury (AKI) leading to chronic kidney disease (CKD). The reduced nitric oxide (NO) bioavailability reported in AAN might contribute to renal function impairment and …
be
(code pays fourni par la source)
Accès ouvert
2016
conference-abstract
OpenAlex
Inès Jadot, Vanessa Colombaro, Blanche Martin, Isabelle Habsch et autres
Introduction and Aims: Aristolochic acid (AA) nephropathy (AAN) is a rapidly progressive tubulointerstitial nephritis of toxic origin characterized by early and transient acute tubular necrosis followed by fibrosis resulting in end-stage renal disease. Interestingly, a reduced nitric oxide (NO) production in AAN …
be
(code pays fourni par la source)
2016
conference-paper
OpenAlex
Inès Jadot, Colombaro, Blanche Martin, Isabelle Habsch et autres
fr
(code pays fourni par la source)